Applied Sciences, Journal Year: 2023, Volume and Issue: 13(8), P. 4872 - 4872
Published: April 13, 2023
The COVID-19 pandemic has impacted the health of millions people worldwide, with many survivors experiencing persistent symptoms and long-term disabilities [...]
Language: Английский
BMC Infectious Diseases, Journal Year: 2023, Volume and Issue: 23(1)
Published: June 21, 2023
Lingering symptoms after acute COVID-19 present a major challenge to ambulatory care services. Since there are reservations regarding their optimal management, we aimed collate all available evidence on the effects of rehabilitation treatments applicable in for these patients.
Language: Английский
Citations
23
Frontiers in Public Health, Journal Year: 2024, Volume and Issue: 12
Published: March 21, 2024
Introduction Long COVID patients experience a decrease in their quality of life due to the symptomatology produced by disease. It is also important understand how long affects both men and women. The objective this study examine impact on Spanish adults from gender perspective. Methods An observational cross-sectional was carried out. Participants were able complete an online questionnaire using platform. A sample 206 people participated study. Results 80.6% women with mean age 46.51 (±8.28) 19.4% 48.03 (±9.50). medium score PAC19-QoL test 141.47 (±24.96) segmented gender, 141.65 (±23.95) for 140.82 (±28.66) men. most common symptoms muscle joint pain (94.6%), fatigue (94.0%), discomfort (92.2%), difficulty concentrating (91.0%), memory loss (88.6%). For included (97.5%) occupying first position, (92.0%), (90.0%), mood disturbances (87.5%). chi-square showed statistical significance ( p < 0.005) socio-demographic information, scores, intensities. Conclusion This shows that there are differences way experienced.
Language: Английский
Citations
5
European Archives of Psychiatry and Clinical Neuroscience, Journal Year: 2024, Volume and Issue: 274(8), P. 1829 - 1845
Published: Jan. 3, 2024
Abstract Post-acute sequelae of COVID-19 can present as multi-organ pathology, with neuropsychiatric symptoms being the most common symptom complex, characterizing long COVID a syndrome significant disease burden for affected individuals. Several typical COVID, such fatigue, depressive and cognitive impairment, are also key features other psychiatric disorders myalgic encephalomyelitis/chronic fatigue (ME/CFS) major disorder (MDD). However, clinically successful treatment strategies still lacking often inspired by options diseases similar clinical presentations, ME/CFS. Acetylcarnitine, shortest metabolite class fatty acid metabolites called acylcarnitines one abundant blood in humans be used dietary/nutritional supplement proven efficacy MDD, ME/CFS disorders. Basic research recent decades has established general, acetylcarnitine particular, important regulators indicators mitochondrial function physiological processes neuroinflammation energy production pathways. In this review, we will compare basis fatigue-associated diseases. We review molecular mechanisms associated altered metabolism potential to interfere these therapeutic agent. Finally, current evidence propose future investigate option COVID.
Language: Английский
Citations
4
Nutrients, Journal Year: 2025, Volume and Issue: 17(7), P. 1287 - 1287
Published: April 7, 2025
Long COVID, characterized by persistent symptoms following COVID-19 infection, significantly impacts individuals' health and daily functioning due to fatigue pain. Focusing on pain, this review addresses nociplastic chronic pain conditions. Interventions designed reduce inflammation, oxidative stress, enhance vagal activity may offer a promising approach managing post-pandemic This presents individual components of food supplements with demonstrated efficacy in one or more conditions, focusing their proposed mechanisms clinical including use post-COVID-19 when available. Many these substances have long history safe an alternative long-term analgesic drug treatment, which is often associated potential side effects. also explores the for synergistic effects combining each other conventional analgesics, considering advantages both patients healthcare system using as adjunctive primary therapies related COVID. While preclinical scientific literature provides mechanistic basis action several control signaling pathways, experience, particularly field COVID-associated still limited. However, reviewed strongly suggests that attainable goal, provided rigorous trials are conducted.
Language: Английский
Citations
0
Medicina, Journal Year: 2023, Volume and Issue: 59(12), P. 2197 - 2197
Published: Dec. 18, 2023
Background and Objectives: In the Western world, back pain sciatica are among main causes of disability absence from work with significant personal, social, economic costs. This prospective observational study aims to evaluate effectiveness a rehabilitation program combined administration Alpha Lipoic Acid, Acetyl-L-Carnitine, Resveratrol, Cholecalciferol in treatment due herniated discs young patients terms resolution, postural alterations, taking painkillers, quality life. Materials Methods: A was conducted on 128 sciatica. We divided sample into 3 groups: Combo group, which received combination protocol daily therapy 600 mg 1000 50 800 UI for 30 days; Reha only protocol; Supplement oral supplementation Cholecalciferol. Clinical assessments were made at time recruitment (T0), days after start (T1), 60 end (T2). The rating scales as follows: Numeric Rating Scale (NRS); Oswestry Disability Questionnaire (ODQ); 36-item Short Form Health Survey (SF-36). All also underwent an instrumental stabilometric evaluation. Results: At T1, group showed statistically superior results compared other groups (p < 0.05), life 0.05). T2, 0.05) From analysis evaluation data, we observed improvement T2 average X groups. Conclusions: supplements anti-inflammatory, pain-relieving, antioxidant action is effective can be useful improving stability.
Language: Английский
Citations
7
F1000Research, Journal Year: 2023, Volume and Issue: 12, P. 368 - 368
Published: May 24, 2023
Language: Английский
Citations
6
Sensors, Journal Year: 2023, Volume and Issue: 23(13), P. 5880 - 5880
Published: June 25, 2023
A new pandemic was declared at the end of 2019 because coronavirus disease (COVID-19). One effects COVID-19 infection is anosmia (i.e., a loss smell). Unfortunately, this olfactory dysfunction persistent in around 5% world's population, and there not an effective treatment for it yet. The aim paper to describe potential non-invasive neurostimulation strategy treating post-COVID-19 patients. In order design strategy, 25 subjects who experienced due underwent assessment while their electroencephalographic (EEG) signals were recorded. These used investigate activation brain regions during process identify which would be suitable neurostimulation. Afterwards, 15 participated evaluation based on applying transcranial direct current stimulation (tDCS) selected related function. results showed that with lower scores obtained greater improvement than other subjects. Thus, tDCS could promising option people have fully regained sense smell following infection.
Language: Английский
Citations
5
Applied Sciences, Journal Year: 2022, Volume and Issue: 12(14), P. 7310 - 7310
Published: July 20, 2022
Many critically ill patients infected with SARS-CoV-2 have been submitted to an intensive care unit (ICU). Patients a infection that survive critical illness are confronted months of physical impairments. To maximize recovery, it is important understand the musculoskeletal involvement in SARS-CoV-2. The aim present study was assess myocellular changes occur throughout first week ICU admission. In n = 22 SARS-CoV-2, biopsy sample from vastus lateralis muscle obtained at day 1–3 and 5–8 following Fluorescence microscopy used type I II fiber size distribution, myonuclear content, tissue capillarization. Transmission electron support quantitative data ultrastructural level. Changes showed large inter-individual variation. average change +309 ± 1834 µm2, ranging −2129 µm2 (−31%) +3375 (+73%). −224 1256 −1410 (−36%) +2592 (+48%). Ultrastructural observations myofibrillar hydropic degeneration, necrosis. This shows admitted suffer substantial damage during These results call for action towards more specialized rehabilitation programs infection.
Language: Английский
Citations
3
F1000Research, Journal Year: 2023, Volume and Issue: 12, P. 368 - 368
Published: April 5, 2023
Language: Английский
Citations
1
Frontiers in Rehabilitation Sciences, Journal Year: 2024, Volume and Issue: 5
Published: Oct. 18, 2024
Background For many people with long COVID (LC), new-onset pain is a debilitating consequence. This study examined the nature of and concomitant symptoms in patients LC to infer mechanisms from relationships between health-related factors. Methods Pain other were evaluated 153 individuals using Self-Administered Leeds Assessment Neuropathic Symptoms Signs, EuroQoL Visual Analog Scale, Quality Life Neurological Disorders. The patient factors analyzed Chi Square independent t -tests. Results 20.3% who reported had neuropathic pain, which was associated lower quality life higher rates cognitive dysfunction compared those non-neuropathic pain. Other similar groups, however heart-related more prevalent mood swings for Conclusions Characterizing NP can aid developing better clinical management strategies. Understanding associations provides imperative foundation future studies further examining pathophysiological underlying development LC.
Language: Английский
Citations
0