Chronotype and lipid metabolism in Arctic Sojourn Workers DOI
Denis Gubin, А. С. Ветошкин,

Nina Shurkevich

et al.

Chronobiology International, Journal Year: 2023, Volume and Issue: 40(9), P. 1198 - 1208

Published: Sept. 2, 2023

This study relates answers to the Munich Chronotype Questionnaire (MCTQ) and Pittsburgh Sleep Quality Index (PSQI) from Arctic Sojourn Workers (ASW) of Yamburg Settlement, 68° Latitude North, 75° Longitude East (n = 180; mean age ± SD; range: 49.2 7.8; 25-66 y; 45% women) Work Experience (ASWE), health status. Chronotype, Mid on Free Days sleep corrected (MSFsc) characteristics ASW were compared those age-matched Tyumen Residents (TR, n 270; 48.4 8.4; 25-69 48% women), 57° 65° East. have earlier MSFsc than TR (70 min in men, p < 0.0001, 45 women, 0.0001). Unlike TR, their was not associated with (r 0.037; 0.627) linked a larger Social Jet Lag (+21 men; 0.003, +18 women; 0.003). These differences due outdoor light exposure (OLE): OLE work (OLEw) or free (OLEf) days significantly different between men less women (OLEw: -31 min; 0.001; OLEf: -24 0.036). ASWE, but age, compromised lipid metabolism men. After accounting for multiple testing, when sex, higher triglycerides high-density lipoprotein ratio, TG/HDL correlated ASWE 0.271, 0.05). In greater SJL lower HDL -0.204; 0.043). Worse proxies metabolic related unfavorable components ASW. Higher systolic (b -0.210; 0.05) diastolic -0.240; blood pressure.

Language: Английский

Higher vulnerability to poor circadian light hygiene in individuals with a history of COVID-19 DOI
Denis Gubin, Yu. V. Boldyreva, Oliver Stefani

et al.

Chronobiology International, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 14

Published: Jan. 6, 2025

Seven-day actigraphy was performed within 1 month in 122 community-dwelling adults (mean age 24.40 y, 31 (25.4%) men) the same city of Tyumen, Russia. Groups with different COVID-19 status (present, COVID-19(+),

Language: Английский

Citations

2

Wearables in Chronomedicine and Interpretation of Circadian Health DOI Creative Commons
Denis Gubin,

Dietmar Weinert,

Oliver Stefani

et al.

Diagnostics, Journal Year: 2025, Volume and Issue: 15(3), P. 327 - 327

Published: Jan. 30, 2025

Wearable devices have gained increasing attention for use in multifunctional applications related to health monitoring, particularly research of the circadian rhythms cognitive functions and metabolic processes. In this comprehensive review, we encompass how wearables can be used study disease. We highlight importance these as markers well-being potential predictors outcomes. focus on wearable technologies sleep research, medicine, chronomedicine beyond domain emphasize actigraphy a validated tool monitoring sleep, activity, light exposure. discuss various mathematical methods currently analyze actigraphic data, such parametric non-parametric approaches, linear, non-linear, neural network-based applied quantify non-circadian variability. also introduce novel actigraphy-derived markers, which personalized proxies status, assisting discriminating between disease, offering insights into neurobehavioral status. lifestyle factors physical activity exposure modulate brain health. establishing reference standards measures further refine data interpretation improve clinical The review calls existing tools methods, deepen our understanding health, develop healthcare strategies.

Language: Английский

Citations

2

The impact of exercise on sleep and sleep disorders DOI Creative Commons
Abdulmenaf Korkutata, Mustafa Korkutata, Michael Lazarus

et al.

Deleted Journal, Journal Year: 2025, Volume and Issue: 2(1)

Published: Feb. 3, 2025

Language: Английский

Citations

1

Narrative review: The role of circadian rhythm on sports performance, hormonal regulation, immune system function, and injury prevention in athletes DOI Creative Commons
Hadi Nobarı, Somayeh Azarian, Saber Saedmocheshi

et al.

Heliyon, Journal Year: 2023, Volume and Issue: 9(9), P. e19636 - e19636

Published: Sept. 1, 2023

ObjectivesThis study was a narrative review of the importance circadian rhythm (CR), describes underlying mechanisms CR in sports performance, emphasizes reciprocal link between CR, endocrine homeostasis and sex differences, unique role clock immune system function coordination.MethodAs study, comprehensive search conducted PubMed, Scopus, Web Science (core collection) databases using keywords "circadian rhythm", "sports performance", "hormonal regulation", "immune system", "injury prevention". Inclusion criteria were studies published English peer-reviewed journals until July 2023. Studies that examined hormonal status, function, injury prevention athletes selected for review.ResultsCR is followed by almost all physiological biochemical activities human body. In humans, superchiasmatic nucleus controls many daily biorhythms under solar time, including sleep-wake cycle. A body literature indicates peak performance essential indicators primarily afternoon hours, evening actions occurs roughly at core temperature. Recent have demonstrated time day exercise performed affects achievement good physical performance. This also shows various biomarkers cellular damage weariness diurnal fluctuations. According to clock, can be synchronized with photonic non-photonic stimuli (i.e., temperature, activity, food intake), feeding patterns diet changes affect redox markers. It links homeostasis, specific coordinating relationship clocks differences.ConclusionThe interaction insufficient sleep on has been established this because it crucial balance training, recovery, duration attain optimal

Language: Английский

Citations

22

The relationship between chronotype and obesity: A systematic review DOI
Seçil Ekiz Erim, Havva Sert

Chronobiology International, Journal Year: 2023, Volume and Issue: 40(4), P. 529 - 541

Published: Feb. 20, 2023

Referring to the hours during a day when person's physical and cognitive functions are active, chronotype indicates differences in individual preferences sleep timing other behaviors. The fact that evening has been associated with adverse health outcomes raised issue of relationship between obesity. This study aims synthesize evidence regarding As part study, PubMed, OVID-LWW, Scopus, Taylor & Francis, ScienceDirect, MEDLINE Complete, Cochrane Library ULAKBIM databases were screened for articles published January 01, 2010 December 31, 2020. quality each was assessed independently by two researchers using "Quality Assessment Tool Quantitative Studies." Upon evaluating screening results, total seven studies, one high six medium quality, included systematic review. rate minor allele (C) genes, which have obesity, SIRT1-CLOCK an additional effect favor resistance against weight loss, is higher individuals chronotype, such observed significantly loss. homeostasis model assessment (HOMA) value, plasma ghrelin levels, tendency toward body mass index (BMI). chronotypes reported adhere less healthy diet more unhealthy behaviors eating patterns. A adjusted seen be effective than conventional hypocaloric therapy terms anthropometric parameters. Most people who eat their main meals late determined lose those early. It shown bariatric surgery loss patients morning patients. successful adapting treatments long-term control chronotypes.

Language: Английский

Citations

20

Blue Light and Temperature Actigraphy Measures Predicting Metabolic Health Are Linked to Melatonin Receptor Polymorphism DOI Creative Commons
Denis Gubin, Konstantin V. Danilenko, Oliver Stefani

et al.

Biology, Journal Year: 2023, Volume and Issue: 13(1), P. 22 - 22

Published: Dec. 30, 2023

This study explores the relationship between light features of Arctic spring equinox and circadian rhythms, sleep metabolic health. Residents (N = 62) provided week-long actigraphy measures, including exposure, which were related to body mass index (BMI), leptin cortisol. Lower wrist temperature (wT) higher evening blue exposure (BLE), expressed as a novel index, nocturnal excess (NEIbl), most sensitive measures associated with BMI. A BMI was linked BLE within distinct time windows. These associations present specifically in carriers MTNR1B rs10830963 G-allele. larger wake-after-sleep onset (WASO), smaller 24 h amplitude earlier phase activity rhythm leptin. Higher cortisol an M10 our other Daylight Deficit Index light, DDIbl. We also found sex-, age- population-dependent differences parametric non-parametric indices BLE, wT physical activity, while there no any characteristics. Overall, this determined markers predictive health showed that these are melatonin receptor polymorphism.

Language: Английский

Citations

19

Impaired Melatonin Secretion, Oxidative Stress and Metabolic Syndrome in Night Shift Work DOI Creative Commons
Sorina Hohor,

Cristina Mandanach,

Andreea Elena Maftei

et al.

Antioxidants, Journal Year: 2023, Volume and Issue: 12(4), P. 959 - 959

Published: April 19, 2023

Metabolic syndrome has been associated in many studies with working shifts. Even if the mechanistic details are not fully understood, forced sleep deprivation and exposure to light, as happens during night shifts, or irregular schedules late very early onset of program, lead a sleep–wake rhythm misalignment, metabolic dysregulation oxidative stress. The cyclic melatonin secretion is regulated by hypothalamic suprachiasmatic nuclei light exposure. At central level, promotes inhibits wake-signals. Beside this role, acts an antioxidant influences functionality cardiovascular system different processes. This review presents data about influence shifts on Assembling from epidemiological, experimental clinical contributes better understanding pathological links between chronodisruption related

Language: Английский

Citations

17

Regularity of bedtime, wake-up time, and time in bed in mid-life: associations with cardiometabolic health markers with adjustment for physical activity and sedentary time DOI Creative Commons
Laura Nauha, Vahid Farrahi,

Heidi Jurvelin

et al.

Journal of Activity Sedentary and Sleep Behaviors, Journal Year: 2024, Volume and Issue: 3(1)

Published: Jan. 5, 2024

Abstract Background Insufficient sleep has been linked to the accumulation of cardiometabolic risks while physical activity acts as a protective factor. Also, regularity may play critical role in maintaining optimal health. This cross-sectional study examined association between device-based regularity, waking behaviors, and health markers, including blood pressure level; abdominal adiposity glucose, insulin, cholesterol. Methods We included 3698 members Northern Finland Birth cohort 1966 who participated follow-up at age 46 years 2012 2014 (women 61%). used seven-day standard deviations bedtime, wake-up time, time bed reflect regularities. As covariates linear regression models, we commonly known potential risk factors (gender, education, marital status, work schedule, smoking alcohol use, mean, chronotype). In addition previous, either sedentary or total covariate (B coefficients with 95% confidence intervals CI). Results When considered other covariates, irregularities were associated unfavorable such higher body mass index (bedtime regularity: 0.194, CI [0.072, 0.316], p = 0.002); diastolic levels (time 0.175, [0.044, 0.306], 0.009); 2-h glucose (wake-up 0.107, [0.030, 0.184], 0.006). only irregular bedtime was waist circumference 0.199, [0.042, 0.356], 0.013). Irregularities not pressure, visceral fat area fasting insulin level after considering (in all, > 0.05). Conclusions middle-aged, appears weaken adverse relationship although interpretation impact remains less conclusive. The clinical significance extent observed associations warrant further investigation.

Language: Английский

Citations

4

Basic research on circadian disruption using animal and human organoid models: a review DOI
Hamideh Rahmati, Behzad Garmabi, Hamed Ghazvini

et al.

Biological Rhythm Research, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 22

Published: Feb. 1, 2025

Language: Английский

Citations

0

Relationship between screen use and internalizing/externalizing problems among preschoolers: the mediation of circadian rhythm DOI
Jia Zhao, Naixue Cui, Yan Li

et al.

Pediatric Research, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 22, 2025

Language: Английский

Citations

0