Polyphenols as Suitable Control for Obesity and Diabetes

The Open Biotechnology Journal, Journal Year: 2018, Volume and Issue: 12(1), P. 219 - 228

Published: Sept. 28, 2018

Modern life is characterized by physical inactivity and poor food choices, which often a prerequisite for unhealthy weight gain overweight/obesity. These factors unlock the emergence of number diseases including diabetes, cardiovascular problems, different types cancer, etc. The pursuit scientists to seek strategies prevent, relieve cure patient leads usage natural compounds potential beneficial effect. Polyphenols are large group naturally occurring secondary metabolites mainly found in plants beverages. presence these seems decrease manifestation miscellaneous disease-causing symptoms. purpose this review synthesize information about polyphenols their controlling obesity diabetes. considered as health-beneficial sources thus could be involved novel preventing diabetes complications.

Language: Английский

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Extraction and analytical approaches for the determination of post-food processing major carcinogens: A comprehensive review towards healthier processed food

Food Chemistry, Journal Year: 2024, Volume and Issue: unknown, P. 141736 - 141736

Published: Oct. 1, 2024

Language: Английский

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Impact of Various Smoking Techniques on Polycyclic Aromatic Hydrocarbon (PAH) Formation in Dry-Cured Pork Neck (Buđola)

Processes, Journal Year: 2024, Volume and Issue: 12(11), P. 2335 - 2335

Published: Oct. 24, 2024

Traditional meat products that are smoked may pose health risks due to polycyclic aromatic hydrocarbons (PAHs). Recently, concerns have grown about the implications of under traditional, uncontrolled conditions. This study compares levels in specimens dry-cured product “Buđola” made traditional smokehouses versus industrial chambers. PAHs were measured upon completion smoking and when production was complete. The findings indicate methods lead higher PAH contamination compared methods. Among 16 analyzed, 10 (NA, AL, FL, ANT, PHE, FLT, BA, PR, BBF, BKF) detected traditionally samples, whereas only 2 AL) found samples by BP all undetectable. PAH4 below quantification limit, while those 28.77 μg·kg−1 for surface layers 21.14 inner layers. total PAH16 content ranged from 4.32 3587.83 μg·kg−1. had lower concentrations overall specific relation surface. results suggest that, a perspective, industrially produced is safer consumption than

Language: Английский

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The Impact of Fat Contents and Different Cooking Processes on the Potential Health Concerns of Polycyclic Aromatic Hydrocarbons in Chicken Doner Kebabs

Polycyclic aromatic compounds, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 20

Published: Oct. 15, 2024

This study investigated the effects of different fat contents and cooking techniques on presence PAHs in chicken doner kebabs, as well dietary exposure potential health risks for Turkish population. The methodology detection quantification 16 PAH compounds samples using high-performance liquid chromatography (HPLC-UV) was validated. limit (LOD), (LOQ), recovery, relative standard deviation (RSD) were found to be 0.44%–1.14%, 1.45%–3.56%, 63.12%–101.50%, 0.14%–3.16%, respectively. Our findings revealed that, among analyzed compounds, BaA most dominant compound, that charcoal technique resulted highest accumulation both BaP PAH4 concentrations kebabs. Additionally, a significant increase levels observed relation higher content. Moreover, it estimated daily intake (EDI) charcoal-grilled, well-done, high-fat samples. As result, fact Margin Exposure (MOE) values calculated across population are above 10,000 indicates low level concern.

Language: Английский

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Food-Borne Polycyclic Aromatic Hydrocarbons and Circadian Disruption

ACS Omega, Journal Year: 2024, Volume and Issue: 9(29), P. 31298 - 31312

Published: July 9, 2024

Circadian disruption has been found to increase the risk of metabolic diseases, brain disorders, and cancer. The aryl hydrocarbon receptor (AhR), responsible for xenobiotic metabolism, is known be activated by certain environmental stimuli, including polycyclic aromatic hydrocarbons (PAHs). Exposure these stimuli may lead diseases related circadian disruption, with AhR activation suggested as a leading cause. Both nuclear translocator (ARNT) translocator-like (BMAL1) are class II basic helix-loop-helix/Per-ARNT-SIM (bHLH-PAS) proteins. These proteins form heterodimers stimulated I bHLH-PAS proteins, locomotor output cycles kaput (CLOCK) AhR. Due their sequential similarity, overactivation toxicants, such PAHs, formation BMAL1, potentially causing disruption. Dysregulation BMAL1 can affect wide range genes, emphasizing its crucial roles. However, this issue not adequately addressed. Previous studies have reported that inhibitory effects phytochemicals on ameliorate induced toxicants. Additionally, some shown preventive misalignment. Therefore, Review aims explore potential strategies prevent food-borne benzo[

Language: Английский

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Environmental Restoration of Contaminated Sediment and Soils: The Role of Organic Amendments in PAH Remediation

Current Pollution Reports, Journal Year: 2024, Volume and Issue: 10(4), P. 580 - 593

Published: Aug. 13, 2024

Abstract Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous; persistent environmental pollutants generated mostly during the incomplete combustion of organic materials. Because dangers that bioavailable PAH fraction pose to receptors, necessity site, degree exposure, and potential for toxicity, remediation PAH-contaminated locations is crucial. Recent findings suggest amendments, such as compost, manure, cover crops, play a crucial role in improving soil/sediment health by increasing matter content, enhancing structure, fostering beneficial microbial activity, removing pollutants. Moreover, they contribute nutrient cycling retention, reducing need synthetic fertilizers, mitigating their adverse effects on environment. In summary, it considered amendments offer promising solutions sustainable remediation, restoration, agriculture practise, promoting productivity while impacts. However, there remains critical gap understanding these materials, preparation application into environment groundwater quality, long-term impacts sediment, water, soil quality. This review paper aims identify future research directions open further questions based what has been published so far this area. Graphical

Language: Английский

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Concentration of polycyclic aromatic hydrocarbons (PAHs) in bread and health risk assessment across the globe: A systematic review and meta‐analysis

Comprehensive Reviews in Food Science and Food Safety, Journal Year: 2024, Volume and Issue: 23(5)

Published: Sept. 1, 2024

Although bread is the principal food in most countries, polycyclic aromatic hydrocarbons (PAHs) may be present and pose a potential risk to consumers. The aim of this review provide comprehensive report on concentration health risks associated with PAHs around world. Various databases, such as Scopus, PubMed, Science Direct, Google Scholar, were searched from their beginnings until December 2023 for systematic review, which included 34 potentially relevant articles data relating 1057 samples. Utilizing multilevel regression modeling approach, study evaluated various factors fuel type, geographical location. Following initial evaluation, 26.47% 20.28% all studies, levels Bap PAH4 higher than permissible limit values, respectively. Based isomer ratios, 55.88% studies presence samples pyrogenic/coal combustion sources. According carcinogenic results, consumers have been exposed moderate or high carcinogenicity. significant are consumption Egypt, Kuwait, Iran, India. Moreover, meta-regression analysis demonstrated significantly toxicity equivalent quotient cancer mean values baked using fossil fuels compared other sources (p < .05). concentrations PAHs, especially Benzo[a]pyrene, serious public risk. Stringent regulations monitoring crucial reduce contamination. Further research necessary develop safe processing methods remove bread.

Language: Английский

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Influence of Smoking and Paprika Spice on the Content of Polycyclic Aromatic Hydrocarbons (PAHs) in the Traditional Spanish Smoked Sausage ‘Botillo del Bierzo’

Foods, Journal Year: 2024, Volume and Issue: 13(24), P. 4089 - 4089

Published: Dec. 17, 2024

The content of polycyclic aromatic hydrocarbons (PAHs) in a traditional Spanish smoked sausage known as ‘Botillo del Bierzo’ was analysed. determination and quantification PAH4 (the sum benzo[a]pyrene, benz[a]anthracene, benzo[b]-fluoranthene chrysene) the were performed using GC–MS. results showed that smoking for 24 h contributes very little to increase PAH levels product, with no significant differences (p < 0.05). paprika used production botillo also content, depending on paprika’s process (smoked, low-smoked, mixed (smoked + unsmoked or low-smoked unsmoked), among them Using lower (unsmoked mixed) enables Bierzo’, accordance Protected Geographical Indication specifications, while maintaining organoleptic characteristics provided by paprika. contamination detected do not pose risk consumer health, benzo[a]pyrene values are well below regulatory limits 5 μg/kg 30 μg/kg, respectively.

Language: Английский

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Effect of Alkaline Salts on Pyrolyzed Solid Wastes in Used Edible Oils: An Attenuated Total Reflectance Analysis of Surface Compounds as a Function of the Temperature

Spectroscopy Journal, Journal Year: 2023, Volume and Issue: 1(2), P. 98 - 110

Published: Sept. 13, 2023

Biochars obtained via the pyrolysis of biomass are very attractive materials from point view their applications and play key roles in current energy context. The characterization these carbonaceous is crucial to determine field application. In this work, a non-conventional (solid wastes used edible oils) was investigated. biochars were characterized using conventional techniques (TG, XRD, SEM-EDX), deep analysis ATR-FTIR performed. This spectroscopic technique, which rapid powerful tool that well adapted study carbon-based materials, employed effect temperature on nature functional groups surface. Moreover, water washing raw sample (containing important quantities inorganic salts) before evidenced salts act as catalysts degradation influence degree condensation (DOC) PAH. it observed contribute retention oxygenated compounds surface solid.

Language: Английский

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Urtica Dioica Leaf Extract Attenuates Oxidative Stress Induced by Environment Pollutant Benzo[a] Pyrene in Mouse Testicular Tissues

The Open Biotechnology Journal, Journal Year: 2023, Volume and Issue: 17(1)

Published: Oct. 10, 2023

Background: Epidemiological studies have shown that elevated levels of air pollutants are associated with various adverse health effects, including infertility. Objective: We aimed to assess the protective effects aqueous Urtica dioica leaf extract against benzo[a]pyrene -induced oxidative damage in mouse testis. Methods: Mice exposed were treated or without for five weeks, and changes body testes weights, messenger RNA activities antioxidant enzymes, plasma testosterone levels, sperm characteristics, testicular tissue histology determined. Results: Exposure remarkably reduced testis expression activity increased lipid peroxidation, decreased count motility, affected morphology viability, damaged seminiferous tubules. Treatment attenuated stress by increasing genes. Further, antioxidative enzyme activity, enhanced improved Conclusion: Aqueous protects from could potentially reverse

Language: Английский

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