A Full-Body IMU-Based Motion Dataset of Daily Tasks by Older and Younger Adults DOI Creative Commons
Loreen Pogrzeba, Evelyn Muschter, Simon Hanisch

et al.

Scientific Data, Journal Year: 2025, Volume and Issue: 12(1)

Published: March 29, 2025

Abstract This dataset (named CeTI-Age-Kinematics ) fills the gap in existing motion capture (MoCap) data by recording kinematics of full-body movements during daily tasks an age-comparative sample with 32 participants two groups: older adults (66–75 years) and younger (19–28 years). The were recorded using sensor suits gloves inertial measurement units (IMUs). features 30 common elemental that are grouped into nine categories, including simulated interactions imaginary objects. Kinematic under well-controlled conditions, repetitions well-documented task procedures variations. It also entails anthropometric body measurements spatial experimental setups to enhance interpretation IMU MoCap relation characteristics situational surroundings. can contribute advancing machine learning, virtual reality, medical applications enabling detailed analyses modeling naturalistic motions their variability across a wide age range. Such technologies essential for developing adaptive systems tele-diagnostics, rehabilitation, robotic planning aim serve broad populations.

Language: Английский

Digital twin assisted surgery, concept, opportunities, and challenges DOI Creative Commons
Lisa Asciak,

Justicia Kyeremeh,

Xichun Luo

et al.

npj Digital Medicine, Journal Year: 2025, Volume and Issue: 8(1)

Published: Jan. 15, 2025

Language: Английский

Citations

2

Artificial Intelligence in Drug Discovery and Development DOI
Kit‐Kay Mak,

Yi-Hang Wong,

Mallikarjuna Rao Pichika

et al.

Springer eBooks, Journal Year: 2023, Volume and Issue: unknown, P. 1 - 38

Published: Jan. 1, 2023

Language: Английский

Citations

35

Artificial Intelligence in Drug Discovery and Development DOI
Kit‐Kay Mak,

Yi-Hang Wong,

Mallikarjuna Rao Pichika

et al.

Springer eBooks, Journal Year: 2024, Volume and Issue: unknown, P. 1461 - 1498

Published: Jan. 1, 2024

Language: Английский

Citations

16

Digital Twins’ Advancements and Applications in Healthcare, Towards Precision Medicine DOI Open Access

Konstantinos Papachristou,

Paraskevi Katsakiori, Panagiotis Papadimitroulas

et al.

Journal of Personalized Medicine, Journal Year: 2024, Volume and Issue: 14(11), P. 1101 - 1101

Published: Nov. 11, 2024

This review examines the significant influence of Digital Twins (DTs) and their variant, Human (DHTs), on healthcare field. DTs represent virtual replicas that encapsulate both medical physiological characteristics-such as tissues, organs, biokinetic data-of patients. These models facilitate a deeper understanding disease progression enhance customization optimization treatment plans by modeling complex interactions between genetic factors environmental influences. By establishing dynamic, bidirectional connections physical objects digital counterparts, these technologies enable real-time data exchange, thereby transforming electronic health records. Leveraging increasing availability extensive historical datasets from clinical trials real-world sources, AI can now generate comprehensive predictions future outcomes for specific patients in form AI-generated DTs. Such also offer insights into potential diagnoses, progression, responses. remarkable paves way precision medicine personalized health, allowing high-level individualized interventions therapies. However, integration faces several challenges, including security, accessibility, bias, quality. Addressing obstacles is crucial to realizing full DHTs, heralding new era personalized, precise, accurate medicine.

Language: Английский

Citations

15

Revolutionizing Healthcare: A Review Unveiling the Transformative Power of Digital Twins DOI Creative Commons
Adithya Balasubramanyam, Richa Ramesh, Rhea Sudheer

et al.

IEEE Access, Journal Year: 2024, Volume and Issue: 12, P. 69652 - 69676

Published: Jan. 1, 2024

In the dynamic landscape of healthcare, Digital Twin (DT) technology has emerged as a transformative force, holding promise revolutionizing patient care and industry practices. This article surveys literature over period 2020 to 2023 on comprehensive exploration DT in elucidating its roles, benefits, implications for smart personalized healthcare. The study addresses fundamental questions concerning potential DT, investigating varied roles benefits revolutionary impact industry, essential requirements crafting system tailored demands research further unveils key layers necessary implementing healthcare system, examining applications that extend from diagnostics treatment strategies. Methodologically, paper navigates through different model discussions, providing structured approach understanding implementation Despite potential, delves into limitations challenges faced by technology, offering balanced perspective current state. conclusion, synthesizes findings, outlines methodologies, discusses challenges, sets stage future research, presenting holistic overview pitfalls, pathways integrating industry.

Language: Английский

Citations

10

Artificial Intelligence-Based Algorithms in Medical Image Scan Segmentation and Intelligent Visual Content Generation—A Concise Overview DOI Open Access

Zofia Rudnicka,

Janusz Szczepański, Agnieszka Pręgowska

et al.

Electronics, Journal Year: 2024, Volume and Issue: 13(4), P. 746 - 746

Published: Feb. 13, 2024

Recently, artificial intelligence (AI)-based algorithms have revolutionized the medical image segmentation processes. Thus, precise of organs and their lesions may contribute to an efficient diagnostics process a more effective selection targeted therapies, as well increasing effectiveness training process. In this context, AI automatization scan increase quality resulting 3D objects, which lead generation realistic virtual objects. paper, we focus on AI-based solutions applied in intelligent visual content generation, i.e., computer-generated three-dimensional (3D) images context extended reality (XR). We consider different types neural networks used with special emphasis learning rules applied, taking into account algorithm accuracy performance, open data availability. This paper attempts summarize current development methods imaging that are XR. It concludes possible developments challenges applications reality-based solutions. Finally, future lines research directions applications, both solutions, discussed.

Language: Английский

Citations

9

A Multidisciplinary Hyper-Modeling Scheme in Personalized In Silico Oncology: Coupling Cell Kinetics with Metabolism, Signaling Networks, and Biomechanics as Plug-In Component Models of a Cancer Digital Twin DOI Open Access
Eleni Kolokotroni, Daniel Abler,

Alokendra Ghosh

et al.

Journal of Personalized Medicine, Journal Year: 2024, Volume and Issue: 14(5), P. 475 - 475

Published: April 29, 2024

The massive amount of human biological, imaging, and clinical data produced by multiple diverse sources necessitates integrative modeling approaches able to summarize all this information into answers specific questions. In paper, we present a hypermodeling scheme combine models cancer aspects regardless their underlying method or scale. Describing tissue-scale cell proliferation, biomechanical tumor growth, nutrient transport, genomic-scale aberrant metabolism, cell-signaling pathways that regulate the cellular response therapy, hypermodel integrates mutation, miRNA expression, data. constituting hypomodels, as well orchestration links, are described. Two types, Wilms (nephroblastoma) non-small lung cancer, addressed proof-of-concept study cases. Personalized simulations actual anatomy patient have been conducted. has also applied predict control after radiotherapy relationship between proliferative activity neoadjuvant chemotherapy. Our innovative holds promise digital twin-based decision support system core future in silico trial platforms, although additional retrospective adaptation validation necessary.

Language: Английский

Citations

9

Radiologists’ perceptions on AI integration: An in-depth survey study DOI

Maurizio Cè,

Simona Ibba, Michaela Cellina

et al.

European Journal of Radiology, Journal Year: 2024, Volume and Issue: 177, P. 111590 - 111590

Published: June 27, 2024

Language: Английский

Citations

9

Deep learning and generative artificial intelligence in aging research and healthy longevity medicine DOI Creative Commons
Dominika Wilczok

Aging, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 16, 2025

With the global population aging at an unprecedented rate, there is a need to extend healthy productive life span. This review examines how Deep Learning (DL) and Generative Artificial Intelligence (GenAI) are used in biomarker discovery, deep clock development, geroprotector identification generation of dual-purpose therapeutics targeting disease. The paper explores emergence multimodal, multitasking research systems highlighting promising future directions for GenAI human animal research, as well clinical application longevity medicine.

Language: Английский

Citations

1

Digital twins and AI transforming healthcare systems through innovation and data-driven decision making DOI
Adel Oulefki, Abbes Amira, Sebti Foufou

et al.

Health and Technology, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 18, 2025

Language: Английский

Citations

1