A LITTLE KNOWN BEE PRODUCT WITH THE POTENTIAL TO BECOME A FUNCTIONAL FOOD AND NUTRITIONAL SUPPLEMENT: APILARNIL DOI Open Access
Rahşan İvgi̇n Tunca, Tülin Arslan

Uludağ Arıcılık Dergisi, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 17, 2024

Beekeeping plays a crucial role in supporting agricultural sustainability and the economy through pollination production of honey other bee products. Among these products is apilarnil, less known substance derived from drone larvae that provides health benefits. Apilarnil rich essential nutrients has been reported to have favorable effects on reproductive system, autonomic nervous system cardiovascular health. In addition its natural medicinal properties, nutritional pharmaceutical potential increasingly recognized, leading commercial apilarnil. This product very important for as it contains amino acids, fatty vitamins, minerals, hormones antioxidants. recognized complete food included various Research emphasizes androgenic, estrogenic, antioxidant immune boosting Animal studies indicate improve health, reduce stress promote growth development. It also shows promise protecting against oxidative improving general this review, information apilarnil uses compiled.

Language: Английский

Royal Jelly: Biological Action and Health Benefits DOI Open Access
Nada Oršolić, Maja Jazvinšćak Jembrek

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(11), P. 6023 - 6023

Published: May 30, 2024

Royal jelly (RJ) is a highly nutritious natural product with great potential for use in medicine, cosmetics, and as health-promoting food. This bee mixture of important compounds, such proteins, vitamins, lipids, minerals, hormones, neurotransmitters, flavonoids, polyphenols, that underlie the remarkable biological therapeutic activities RJ. Various bioactive molecules like 10-hydroxy-2-decenoic acid (10-HDA), antibacterial protein, apisin, major royal specific peptides apisimin, royalisin, royalactin, apidaecin, defensin-1, jelleins are characteristic ingredients RJ shows numerous physiological pharmacological properties, including vasodilatory, hypotensive, antihypercholesterolaemic, antidiabetic, immunomodulatory, anti-inflammatory, antioxidant, anti-aging, neuroprotective, antimicrobial, estrogenic, anti-allergic, anti-osteoporotic, anti-tumor effects. Moreover, may reduce menopause symptoms improve health reproductive system, liver, kidneys, promote wound healing. article provides an overview molecular mechanisms underlying beneficial effects various diseases, aging, aging-related complications, special emphasis on components their properties. The data presented should be incentive future clinical studies hopefully will advance our knowledge about facilitate development novel RJ-based opportunities improving human well-being.

Language: Английский

Citations

24
Romanian Bee Product Analysis: Chemical Composition, Antimicrobial Activity, and Molecular Docking Insights DOI Creative Commons
Silvia Pătruică, Mukhtar Adeiza Suleiman, Anca Hulea

et al.

Foods, Journal Year: 2024, Volume and Issue: 13(10), P. 1455 - 1455

Published: May 8, 2024

Bee products are considered true wonders of nature, used since ancient times, and studied even today for their various biological activities. In this study, we hypothesise that Romanian bee from different origins (micro apiary products, lyophilised forms, commercial) exhibit distinct chemical compositions, influencing An LC-MS analysis revealed varied polyphenolic content patterns, with cumaric acid, ferulic rosmarinic quercitine identified in significant amounts across all samples. Primary anti-inflammatory evaluation phases, including the inhibition haemolysis values protein denaturation, unveiled a range protective effects on red blood cells (RBC) proteins, contingent upon sample concentration. Antimicrobial activity assessments against 12 ATCC strains 6 pathogenic isolates demonstrated varying efficacy, propolis samples showing low royal jelly forms displaying moderate effectiveness, apilarnin exhibiting good inhibitory activity, mostly Gram-positive bacteria. Notably, form emerged as most promising sample, yielding best results activities assessed. Furthermore, molecular docking was employed to elucidate potential compounds these by targeting putative bacterial fungal proteins. Results showed rutin exhibited strong binding energies interactions antimicrobial proteins bacteria (−9.7 kcal/mol −7.6 kcal/mol) fungi (−9.5 −8.1 kcal/mol). The findings study support use purposes biologically active eco-friendly proportion while providing valuable insights into mechanism action.

Language: Английский

Citations

4
Assessing the Influence of Stimulatory Feeding of Bee Colonies on Mineral Composition and Antioxidant Activity of Bee Venom DOI Creative Commons

Adrian Dan Rășinar,

Isidora Radulov, Adina Berbecea

et al.

Insects, Journal Year: 2025, Volume and Issue: 16(4), P. 423 - 423

Published: April 17, 2025

Bee venom is a complex natural beekeeping product, traditionally used in apitherapy, with wide spectrum of pharmacological properties. Research on the mineral content bee limited and challenging to compare across studies due varying regions where they are conducted. Our study aimed assess how supplementary feeding colonies probiotic products, essential oils, as well rapeseed acacia nectar pollen, affects antioxidant activity venom. The parameters analyzed included moisture, pH, dry matter, ash, impurities, levels macro micro elements activity. moisture samples was 10–22%, pH ranged between 5.84 6.41. element showed that potassium most abundant element, followed by calcium, magnesium, phosphorus. Pb identified collected indicating lead pollution area hives were located case three harvests. In all samples, highest DPPH radical scavenging observed at concentration 2.00 mg/mL, sample V6 showing maximum value 87.05%.

Language: Английский

Citations

0
Enzyme Inhibitory, Physicochemical, and Phytochemical Properties and Botanical Sources of Honey, Bee Pollen, Bee Bread, and Propolis Obtained from the Same Apiary DOI Creative Commons
Yusuf Can Gerçek, Eda Dagsuyu, Fatma Nur Baştürk

et al.

Antioxidants, Journal Year: 2024, Volume and Issue: 13(12), P. 1483 - 1483

Published: Dec. 5, 2024

Bee products are an important source of nutrients and bioactive phytochemicals. This study aimed to determine the chemical composition (proximate composition, general phytochemical sugar, phenolic profiles) four different (honey, bee pollen, bread, propolis), obtained from same apiary, as well assess their biological activity through antioxidant enzyme inhibition assays (α-amylase, α-glucosidase, lipase, AchE, neuraminidase, angiotensin-converting enzyme, urease, trypsin, tyrosinase, carbonic anhydrase, thioredoxin reductase, adenosine deaminase). Clear differences were observed among samples in terms both activity. The analysis revealed that pollen exhibited highest carbohydrate content (87.9%), while propolis was identified richest compounds (14,858.9 mg/kg) analyzed samples. Propolis all applied (CUPRAC, DPPH•, ABTS•+) most assays. Notably, α-glucosidase comparable reference standard. In addition, honey remarkable trypsin inhibition, also These findings highlight diverse bioactivities hive products, which could play a key role promoting health preventing diseases.

Language: Английский

Citations

2
A LITTLE KNOWN BEE PRODUCT WITH THE POTENTIAL TO BECOME A FUNCTIONAL FOOD AND NUTRITIONAL SUPPLEMENT: APILARNIL DOI Open Access
Rahşan İvgi̇n Tunca, Tülin Arslan

Uludağ Arıcılık Dergisi, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 17, 2024

Beekeeping plays a crucial role in supporting agricultural sustainability and the economy through pollination production of honey other bee products. Among these products is apilarnil, less known substance derived from drone larvae that provides health benefits. Apilarnil rich essential nutrients has been reported to have favorable effects on reproductive system, autonomic nervous system cardiovascular health. In addition its natural medicinal properties, nutritional pharmaceutical potential increasingly recognized, leading commercial apilarnil. This product very important for as it contains amino acids, fatty vitamins, minerals, hormones antioxidants. recognized complete food included various Research emphasizes androgenic, estrogenic, antioxidant immune boosting Animal studies indicate improve health, reduce stress promote growth development. It also shows promise protecting against oxidative improving general this review, information apilarnil uses compiled.

Language: Английский

Citations

0