A comprehensive kinetics and thermodynamics studies of oil extraction from West African avocado: Towards sustainable development
Industrial Crops and Products,
Journal Year:
2025,
Volume and Issue:
225, P. 120449 - 120449
Published: Jan. 11, 2025
Language: Английский
The Therapeutic Potential of Kiwi Extract as a Source of Cysteine Protease Inhibitors on DNCB-Induced Atopic Dermatitis in Mice and Human Keratinocyte HaCaT Cells
Hye Ryeon Yang,
No information about this author
Most Nusrat Zahan,
No information about this author
Du Hyeon Hwang
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et al.
International Journal of Molecular Sciences,
Journal Year:
2025,
Volume and Issue:
26(4), P. 1534 - 1534
Published: Feb. 12, 2025
The
discovery
of
effective
cysteine
protease
inhibitors
with
crude
protein
kiwi
extracts
(CPKEs)
has
created
novel
challenges
and
prospects
for
pharmaceutical
development.
Despite
extensive
research
on
CPKEs,
limited
been
conducted
treating
atopic
dermatitis
(AD).
Therefore,
the
objective
this
work
was
to
investigate
anti-inflammatory
effects
CPKEs
TNF-α
activation
in
a
HaCaT
cell
model
DNCB
(1-chloro-2,
4-dinitrochlorobenzene)-induced
animal
model.
molecular
weight
CPKE
determined
using
SDS-PAGE
under
non-reducing
(17
kDa
22
kDa)
reducing
conditions
(25
kDa,
15
kDa),
whereas
gelatin
zymography
performed
examine
CPKE's
inhibitory
impact
(actinidin
papain)
activity.
Moreover,
remains
stable
at
60
°C,
pH
levels
varying
from
4
11,
as
by
azocasein
assay.
treatment
decreased
phosphorylation
mitogen-activated
kinase
(MAPK)
Akt,
along
nuclear
factor-kappa
B
(NF-κB)-p65
tumor
necrosis
factor-α
(TNF-α)-stimulated
cells.
Five-week-old
BALB/c
mice
were
treated
act
an
AD-like
topical
application
DNCB-treated
three
weeks
substantially
clinical
severity
epidermal
thickness
reduced
eosinophil
infiltration
mast
cells
into
ear
skin
tissues.
These
findings
imply
that
derived
kiwifruit
might
be
promising
therapy
option
inflammatory
diseases
such
AD.
Language: Английский
Cardio-Protective-Promoting Properties of Functional Foods Inducing HDL-Cholesterol Levels and Functionality
Athina Velissaridou,
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Ellie Panoutsopoulou,
No information about this author
Vasileios Prokopiou
No information about this author
et al.
Nutraceuticals,
Journal Year:
2024,
Volume and Issue:
4(4), P. 469 - 502
Published: Sept. 30, 2024
High-density
lipoprotein
(HDL)
has
been
proposed
to
provide
cardio-protective
properties
through
the
functionality
of
its
anti-inflammatory
and
antioxidant
enzymatic
machinery.
Within
this
article,
beneficial
effects
several
functional
foods
on
HDL
levels
for
cardio-protection
are
thoroughly
reviewed.
Emphasis
is
given
their
health-promoting
cardiovascular
system
benefits
HDL,
which
act
either
solely
or
synergistically
as
an
adjuvant
approach
with
well-established
anti-atherogenic
therapies.
Promising
outcomes
from
both
in
vitro
vivo
studies
animal
models
clinical
trials,
outline
such
functionality,
discussed.
The
mechanisms
obtained
antioxidant,
anti-inflammatory,
antithrombotic,
activities
containing
natural
bioactives
also
outlined.
Limitations
future
perspectives
overall
that
these
bioactive
compounds
exert
important
ingredients
induce
HDL-related
strengthen
health
Language: Английский
Evaluating the Efficacy of Actinidia deliciosa (Kiwi Fruit) Extract in Inhibiting Pseudomonas aeruginosa Biofilm Formation: An In Vitro Study With Therapeutic Implications
Michael Zacharia Mathew,
No information about this author
Abirami Arthanari,
No information about this author
G. Shankar Ganesh
No information about this author
et al.
Cureus,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Sept. 24, 2024
Background
Gram-negative
Language: Английский