From Stents to Smart Implants Employing Biomimetic Materials: The Impact of 4D Printing on Modern Healthcare
Biomimetics,
Journal Year:
2025,
Volume and Issue:
10(2), P. 125 - 125
Published: Feb. 19, 2025
The
sector
of
4D
printing
represents
a
new
frontier
in
additive
manufacturing
that
allows
for
material's
capability
to
adapt
and
respond
various
stimuli,
such
as
thermal
transitions,
humidity,
pH
levels.
adaptability
material
has
great
potential
healthcare
applications,
especially
designing
personalized
responsive
medical
devices.
This
article
looks
into
the
revolutionary
applications
printing,
referencing
self-repairable
implants,
smart
stents,
drug
delivery
systems,
response-based
prosthetic
advances
3D
have
created
platform
innovations
take
place,
while
properties
unique
allow
methods
tackling
existing
health
issues.
However,
large-scale
application
medicine
is
currently
hampered
by
limitations,
regulation
challenges,
financial
challenges.
In
spite
these
ongoing
technologies,
combined
with
artificial
intelligence
machine
learning,
provide
surpass
hence
improving
precision,
efficacy,
personalization
work
outlines
at
areas
future,
analyzes
contributing
healthcare,
recognizing
challenges
need
be
overcome
order
unlock
its
full
potential.
Language: Английский
Regenerative Medicine in Plastic Surgery: The Role of Stem Cells and Bioprinting
Regenesis repair rehabilitation.,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 1, 2025
Language: Английский
The rise of 3D bioprinting: from organs to personalized medicine
Patient-Oriented Medicine and Pharmacy,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 7, 2025
Bioprinting
has
emerged
as
a
groundbreaking
technology
in
the
realms
of
organ
transplantation
and
regenerative
medicine,
addressing
critical
challenges
such
shortages
tissue
repair.
This
review
explores
technological
advancements
innovations
bioprinting,
highlighting
state-of-the-art
techniques,
bioinks,
applications
engineering.
Key
milestones
printing
functional
tissues,
including
vascularized
transplantable
prototypes,
are
discussed
alongside
role
bioprinting
personalized
where
patient-oriented
models
revolutionizing
drug
testing
therapeutic
strategies.
Furthermore,
this
article
examines
ethical
considerations
associated
with
offering
insights
into
its
future
potential
to
transform
global
healthcare.
Language: Английский
Optimization of LCD-Based 3D Printing for the Development of Clotrimazole-Coated Microneedle Systems
Materials,
Journal Year:
2025,
Volume and Issue:
18(7), P. 1580 - 1580
Published: March 31, 2025
Fungal
infections
pose
a
significant
global
health
problem,
affecting
20–25%
of
the
population
and
contributing
to
over
3.75
million
deaths
annually.
Clotrimazole
(CLO)
is
widely
used
topical
antifungal
drug,
but
its
efficacy
limited
by
poor
penetration
through
stratum
corneum.
Microneedle
(MN)
systems,
composed
micron-scale
structures
arranged
on
patch,
offer
promising
strategy
overcome
outermost
skin
barrier
enhance
drug
into
deeper
layers.
However,
optimizing
MN
design,
particularly
in
terms
size,
shape,
fabrication
technology,
essential
for
efficient
delivery.
This
study
aimed
develop
CLO-coated
systems
using
an
Liquid
Crystal
Display
(LCD)-based
3D
printing
technique
thin-film
dip-coating
method.
A
comprehensive
optimization
parameters,
including
anti-aliasing,
layer
thickness,
curing
time,
angle,
was
conducted
ensure
desired
mechanical
properties.
The
optimized
MNs
were
coated
with
either
suspension
or
ethanol-based
CLO-hydrogels,
ethanol
hydrogel
demonstrating
superior
characteristics.
Additionally,
investigated
how
microneedle
geometry
coating
formulation
influenced
release.
Antifungal
activity
against
reference
clinical
origin
Candida
albicans
strains
varied
significantly
depending
formulation.
Finally,
acute
toxicity
test
confirmed
no
toxic
effects
Aliivibrio
fischeri,
indicating
potential
biocompatibility
safety
developed
MN-based
delivery
system.
Language: Английский
Bioprinting in Organ Transplantation: From Experimental Models to Clinical Prospects
Brazilian Journal of Transplantation,
Journal Year:
2025,
Volume and Issue:
28(1)
Published: April 25, 2025
Background:
Bioprinting
has
emerged
as
an
innovative
technology
in
organ
transplantation
and
regenerative
medicine,
aiming
to
address
pressing
challenges
such
the
shortage
of
donor
organs
need
for
effective
tissue
repair.
By
leveraging
advanced
3D
printing
techniques,
bioprinting
enables
fabrication
functional
tissues
with
precise
architectural
biological
properties.
Methods:
This
review
provides
in-depth
analysis
latest
advancements
bioprinting,
focusing
on
cutting-edge
development
bioinks,
their
applications
engineering.
It
examines
significant
breakthroughs
creation
vascularized
transplantable
prototypes
explores
role
personalized
medicine.
Results:
The
findings
highlight
transformative
impact
biomedical
field,
particularly
drug
testing,
therapeutic
modeling,
patient-specific
treatment
strategies.
Additionally,
key
challenges—including
technological
limitations,
ethical
concerns,
regulatory
considerations—are
discussed
provide
a
comprehensive
understanding
field’s
progress
potential
obstacles.
Conclusion:
holds
immense
promise
revolutionizing
global
healthcare
by
offering
solutions
shortages
advancing
However,
continued
research
innovation
are
necessary
overcome
existing
facilitate
its
clinical
translation
into
mainstream
medical
practice.
Language: Английский
Bioimpressão no Transplante de Órgãos: Dos Modelos Experimentais às Perspectivas Clínicas
Brazilian Journal of Transplantation,
Journal Year:
2025,
Volume and Issue:
28(1)
Published: April 25, 2025
Introdução:
A
bioimpressão
despontou
como
uma
tecnologia
inovadora
no
transplante
de
órgãos
e
na
medicina
regenerativa,
visando
solucionar
desafios
urgentes,
a
escassez
doadores
necessidade
reparo
eficaz
tecidos.
Ao
aproveitar
as
técnicas
avançadas
impressão
3D,
permite
fabricação
tecidos
funcionais
com
propriedades
arquitetônicas
biológicas
precisas.
Métodos:
Esta
revisão
fornece
análise
detalhada
dos
últimos
avanços
em
bioimpressão,
concentrando-se
ponta,
desenvolvimento
biotintas
suas
aplicações
engenharia
Ela
examina
os
significativos
criação
protótipos
vascularizados
transplantáveis
explora
função
da
personalizada.
Resultados:
As
descobertas
destacam
o
impacto
transformador
campo
biomédico,
particularmente
testes
medicamentos,
modelagem
terapêutica
estratégias
tratamento
específicas
para
paciente.
Além
disso,
principais
—
incluindo
limitações
tecnológicas,
preocupações
éticas
considerações
regulatórias
são
discutidos
fornecer
compreensão
abrangente
do
progresso
possíveis
obstáculos.
Conclusão:
é
imensamente
promissora
revolucionar
saúde
global,
oferecendo
soluções
avanço
regenerativa.
No
entanto
pesquisa
inovação
contínuas
necessárias
superar
existentes
facilitar
sua
tradução
clínica
prática
médica
convencional.