Recent Trends in Biologically Synthesized Metal Nanoparticles and their Biomedical Applications: a Review

Biological Trace Element Research, Journal Year: 2023, Volume and Issue: 202(7), P. 3383 - 3399

Published: Oct. 25, 2023

Language: Английский

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Biosynthesis of Copper Nanoparticles with Medicinal Plants Extracts: From Extraction Methods to Applications

Micromachines, Journal Year: 2023, Volume and Issue: 14(10), P. 1882 - 1882

Published: Sept. 30, 2023

Copper nanoparticles (CuNPs) can be synthesized by green methods using plant extracts. These are more environmentally friendly and offer improved properties of the NPs in terms biocompatibility functional capabilities. Traditional medicine has a rich history utilization herbs for millennia, offering viable alternative or complementary option to conventional pharmacological medications. Plants traditional herbal use those with medicinal candidates used obtain due their high complex content biocompounds different redox capacities that provide dynamic reaction environment NP synthesis. Other synthesis conditions, such as salt precursor concentration, temperature, time synthesis, pH, have significant effect on characteristics NPs. This paper will review some compounds from plants, extract obtention alternatives, extracts, how they relate process. Additionally, document includes diverse applications associated CuNPs, starting antibacterial potential metabolic disease treatment, vegetable tissue culture, therapy, cardioprotective effect, among others.

Language: Английский

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Myco-synthesized copper oxide nanoparticles using harnessing metabolites of endophytic fungal strain Aspergillus terreus: an insight into antibacterial, anti-Candida, biocompatibility, anticancer, and antioxidant activities

BMC Complementary Medicine and Therapies, Journal Year: 2023, Volume and Issue: 23(1)

Published: July 22, 2023

The overuse of antibiotics leads to the emergence antibiotic-resistant microbes which causes high mortality worldwide. Therefore, synthesis new active compounds has multifunctional activities are main challenge. Nanotechnology provides a solution for this issue.The endophytic fungal strain Aspergillus terreus BR.1 was isolated from healthy root Allium sativum and identified using internal transcribed spacer (ITS) sequence analysis. copper oxide nanoparticles (CuO-NPs) were synthesized by harnessing metabolites strain. UV-Visble spectroscopy, Fourier-transform infrared spectroscopy (FT-IR), Transmission electron micrscopy (TEM), Energy dispersive X-ray (EDX), diffraction (XRD), Dynamic light scattering (DLS), zeta potential (ζ) used characterization CuO-NPs. activity against different pathogenic bacteria Candida species investigated agar well-diffusion method. biocombatibility anticancer assessed MTT assay scavenging DPPH investigate antioxidant CuO-NPs.Data showed successful formation crystalline nature spherical shape CuO-NPs with sizes in ranges 15-55 nm. EDX reveals that as-formed sample contains ions C, O, Cl, Cu weight percentages 18.7, 23.82, 11.31, 46.17%, respectively. DLS ζ-potential homogeneity stability polydispersity index (PDI) 0.362 ζ-value - 26.6 mV. exhibited promising antibacterial anti-Candida (concentration-dependent) minimum inhibitory concentration (MIC) values 25-50 µg mL-1. Moreover, mediated-CuO-NPs targeted cancer cells MCF7 PC3 at low IC50 concentrations 159.2 ± 4.5 116.2 3.6 mL-1, respectively as compared normal (Vero Wi38 value 220.6 3.7 229.5 2.1 respectively). biosynthesized detected method 80.5 1.2% 1000 mL-1 decreased 20.4 4.2% 1.9 ascorbic acid (control) 97.3 0.2 37.5 1.3% same concentrations, respectively.The can be integrated into various biomedical theraputic applications.

Language: Английский

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Green synthesis of copper oxide nanoparticles using okra (Abelmoschus esculentus) fruit extract and assessment of their cytotoxicity and photocatalytic applications

Environmental Technology & Innovation, Journal Year: 2023, Volume and Issue: 32, P. 103300 - 103300

Published: July 25, 2023

In this research, copper oxide nanoparticles (CuO-NPs) were biosynthesized through a simple, quick, and green manner by the exertion of okra (Abelmoschus esculentus) fruit extract as stabilizer reducing agent. TGA/DTA, UV–Vis, DRS, FTIR, XRD, BET, TEM, FESEM/EDX, PSA analyses used to characterize CuO-NPs. The XRD analysis CuO-NPs exhibited monoclinic structure crystallizes in size about 25 nm. optical surface characteristics examined results DRS BET analyses, while their area was observed be 5.6 m2/g. absorption spectra NPs revealed peak at around 320 addition, FESEM/TEM/PSA images displayed spherical shape 20 effectiveness photocatalyst testing ability degrade various dyes under UV light. According outcomes after 210 min, degradation percentages Eriochrome black T (EBT), Rhodamine B (RhB), Methylene blue (MB) approximately 88, 96, 88%, respectively. anticancer efficacy against HeLa cancer cell line 24, 48, 72 h (IC50=1000, 500, 250 μg/mL, respectively) significant, whereas lower cytotoxic effects induced on normal fibroblast L929 when compared that cells. viability cells concentration 1000 μg/mL decreased 74, 71, 65% h,

Language: Английский

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A review on copper-based nanoparticles as a catalyst: synthesis and applications in coupling reactions

Journal of Materials Science, Journal Year: 2024, Volume and Issue: 59(15), P. 6169 - 6205

Published: March 24, 2024

Language: Английский

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