Oral Microbiome Research in Biopsy Samples of Oral Potentially Malignant Disorders and Oral Squamous Cell Carcinoma and Its Challenges DOI Creative Commons
Bruno Špiljak, Petar Ozretić, Ana Andabak Rogulj

et al.

Applied Sciences, Journal Year: 2024, Volume and Issue: 14(23), P. 11405 - 11405

Published: Dec. 7, 2024

This study aims to evaluate the potential benefits and challenges of integrating oral microbiome research into clinical management potentially malignant disorders (OPMD) squamous cell carcinoma (OSCC). The has gained significant attention for its role in pathogenesis progression these conditions, with emerging evidence suggesting value as a diagnostic prognostic tool. By critically analyzing current methodological considerations, this manuscript examines whether analysis biopsy samples can aid early detection, prognosis, OPMD OSCC. complexity dynamic nature require multifaceted approach fully understand utility. Based on review, we conclude that studying context holds promise but also faces notable challenges, including variability need standardization. Ultimately, addresses question, “Should such be undertaken, given intricate interactions various factors inherent obstacles involved?”, emphasizes importance further optimize applications improve patient outcomes.

Language: Английский

Oral Microbiome Research in Biopsy Samples of Oral Potentially Malignant Disorders and Oral Squamous Cell Carcinoma and Its Challenges DOI Creative Commons
Bruno Špiljak, Petar Ozretić, Ana Andabak Rogulj

et al.

Applied Sciences, Journal Year: 2024, Volume and Issue: 14(23), P. 11405 - 11405

Published: Dec. 7, 2024

This study aims to evaluate the potential benefits and challenges of integrating oral microbiome research into clinical management potentially malignant disorders (OPMD) squamous cell carcinoma (OSCC). The has gained significant attention for its role in pathogenesis progression these conditions, with emerging evidence suggesting value as a diagnostic prognostic tool. By critically analyzing current methodological considerations, this manuscript examines whether analysis biopsy samples can aid early detection, prognosis, OPMD OSCC. complexity dynamic nature require multifaceted approach fully understand utility. Based on review, we conclude that studying context holds promise but also faces notable challenges, including variability need standardization. Ultimately, addresses question, “Should such be undertaken, given intricate interactions various factors inherent obstacles involved?”, emphasizes importance further optimize applications improve patient outcomes.

Language: Английский

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