Chitosan/hydroxyapatite hydrogels for localized drug delivery and tissue engineering: A Review DOI Creative Commons

Khashayar Khodaverdi,

Seyed Morteza Naghib, Masoud Mozafari

et al.

Carbohydrate Polymer Technologies and Applications, Journal Year: 2024, Volume and Issue: unknown, P. 100640 - 100640

Published: Dec. 1, 2024

Language: Английский

Functional Scaffolds for Bone Tissue Regeneration: A Comprehensive Review of Materials, Methods, and Future Directions DOI Creative Commons

Emily Ann Todd,

Nicholas A. Mirsky, Bruno Luís Graciliano Silva

et al.

Journal of Functional Biomaterials, Journal Year: 2024, Volume and Issue: 15(10), P. 280 - 280

Published: Sept. 25, 2024

Bone tissue regeneration is a rapidly evolving field aimed at the development of biocompatible materials and devices, such as scaffolds, to treat diseased damaged osseous tissue. Functional scaffolds maintain structural integrity provide mechanical support defect site during healing process, while simultaneously enabling or improving through amplified cellular cues between scaffold native tissues. Ample research on functionalization has been conducted improve scaffold–host interaction, including fabrication techniques, biomaterial selection, surface modifications, integration bioactive molecular additives, post-processing modifications. Each these methods plays crucial role in not only but actively participate process bone joint surgery. This review provides state-of-the-art, comprehensive overview scaffold-based strategies used engineering, specifically for regeneration. Critical issues obstacles are highlighted, applications advances described, future directions identified.

Language: Английский

Citations

14

Smart biomaterials in healthcare: Breakthroughs in tissue engineering, immunomodulation, patient-specific therapies, and biosensor applications DOI Creative Commons
Ansheed Raheem, Kalpana Mandal, Swarup Biswas

et al.

Applied Physics Reviews, Journal Year: 2025, Volume and Issue: 12(1)

Published: March 1, 2025

Smart biomaterials have significantly impacted human healthcare by advancing the development of medical devices designed to function within tissue, mimicking behavior natural tissues. While intelligence has evolved from inert active over past few decades, smart take this a step further making their surfaces or bulk respond based on interactions with surrounding tissues, imparting outcomes similar tissue functions. This interaction helps in creating stimuli-responsive biomaterials, which can be useful engineering, regenerative medicine, autonomous drug delivery, orthopedics, and much more. Traditionally, material engineering focused refining static properties accommodate them body without evoking an immune response, was major obstacle unrestricted operation. review highlights explains various approaches currently under research for developing that tune responses bodily factors like temperature, pH, ion concentration external magnetism, light, conductivity. Applications soft hard 4D printing, scaffold design are also discussed. The advanced application microfluidics, organ-on-a-chip models, extensively benefits intrinsic discussed below. elaborates how biomaterial could revolutionize biosensor applications, thereby improving patient care quality. We delineate limitations key challenges associated providing insights into path forward outlining future directions next-generation will facilitate clinical translation.

Language: Английский

Citations

1

Emerging Applications of Smart Hydrogel Nanocomposites in 3D Printing DOI
Mohammad Heidari,

Farangis Shahi,

Hana Afshar

et al.

Polymers for Advanced Technologies, Journal Year: 2024, Volume and Issue: 35(12)

Published: Dec. 1, 2024

ABSTRACT This review provides a comprehensive overview of the emerging applications stimuli‐responsive hydrogels in 3D printing, emphasizing their transformative potential creating adaptive and multifunctional structures. Stimuli‐responsive hydrogels, including magneto‐, thermo‐, pH‐, moisture‐, solvent‐, photo‐responsive varieties, have gained significant attention due to ability undergo dynamic changes response specific environmental stimuli. The begins by exploring fundamental characteristics fabrication methods used additive manufacturing, highlighting exceptional adaptability programmability. It then delves into various across diverse fields, soft robotics, tissue engineering, drug delivery systems, wearable electronics, food technology, electromagnetic interference shielding, anti‐counterfeiting technologies. By integrating latest advancements printing techniques, this aims offer insights how are enabling development innovative, intelligent, environmentally responsive systems. future perspectives section discusses challenges opportunities for advancing use suggesting directions research that could push boundaries functional materials programmable

Language: Английский

Citations

4

Multi-material 4D Printing and 3D Patterned Metallization Enables Smart Architectures DOI
Kewei Song,

Chunfeng Xiong,

Ze Zhang

et al.

Composites Part B Engineering, Journal Year: 2025, Volume and Issue: 295, P. 112218 - 112218

Published: Feb. 1, 2025

Language: Английский

Citations

0

4D Printing in Dynamic and Adaptive Bone Implants: Progress in Bone Tissue Engineering DOI

Aayush Prakash,

Rishabha Malviya,

Sathvik Belagodu Sridhar

et al.

Bioprinting, Journal Year: 2024, Volume and Issue: unknown, P. e00373 - e00373

Published: Nov. 1, 2024

Language: Английский

Citations

3

Chitosan/hydroxyapatite hydrogels for localized drug delivery and tissue engineering: A Review DOI Creative Commons

Khashayar Khodaverdi,

Seyed Morteza Naghib, Masoud Mozafari

et al.

Carbohydrate Polymer Technologies and Applications, Journal Year: 2024, Volume and Issue: unknown, P. 100640 - 100640

Published: Dec. 1, 2024

Language: Английский

Citations

2