Sensors,
Journal Year:
2025,
Volume and Issue:
25(5), P. 1459 - 1459
Published: Feb. 27, 2025
Oral
cancer
continues
to
cause
profound
suffering
and
is
associated
with
high
mortality
rates.
Early
detection
techniques
are
crucial
in
enhancing
patient
outcomes.
This
review
paper
thoroughly
evaluates
the
significance
of
biomarkers
recent
advancements
oral
detection,
emphasizing
cutting-edge
electrochemical
methods.
The
provides
an
epidemiological
etiological
overview,
outlining
its
clinical
importance
reviewing
current
state
art
Despite
considerable
progress,
conventional
methods
exhibit
limitations
such
as
invasiveness,
long
wait
times,
a
lack
accuracy,
creating
critical
need
for
more
robust
technologies.
emphasizes
biomarkers,
which
considered
promising
cues
early
facilitating
development
innovative
biosensing
seeks
illuminate
advances
precision
diagnostics,
along
usage
artificial
intelligence
strategies,
ultimately
contributing
significant
progress
battle
against
cancer.
Journal of Materials Chemistry B,
Journal Year:
2022,
Volume and Issue:
11(1), P. 33 - 54
Published: Nov. 15, 2022
In
recent
years,
electrochemical
biosensors
(ECBSs)
have
shown
significant
potential
for
real-time
disease
diagnosis
and
in
situ
physical
condition
monitoring.
As
a
multi-constituent
oral
fluid
comprising
various
signaling
biomarkers,
saliva
has
drawn
much
attention
the
field
of
point-of-care
(POC)
testing.
particular,
during
outbreak
COVID-19
pandemic,
ECBSs
which
hold
simplicity
single-step
assay
compared
with
multi-step
traditional
testing
methods
are
expected
to
relieve
human
economic
burden
caused
by
massive
long-term
sample
process.
Noteworthily,
detection
SARS-CoV-2
already
been
developed
may
replace
current
methods.
Furthermore,
scope
expanded
from
routine
indices
such
as
sugar
uric
acid
abnormal
biomarkers
early-stage
drug
level
monitoring,
further
facilitated
evolution
last
5
years.
This
review
is
divided
into
several
main
sections.
First,
we
discussed
latest
advancements
representative
research
on
Then,
focused
novel
kind
ECBS,
organic
transistors
(OECTs),
great
advantages
high
sensitivity
signal-to-noise
ratio
on-site
detection.
Finally,
application
integrated
portable
platforms
cavities,
lead
powerful
auxiliary
means
telemedicine,
also
discussed.
Cancers,
Journal Year:
2024,
Volume and Issue:
16(18), P. 3156 - 3156
Published: Sept. 14, 2024
Oral
cavity
and
lip
cancers
are
the
16th
most
common
cancer
in
world.
It
is
widely
known
that
a
lack
of
public
knowledge
about
precancerous
lesions,
oral
symptoms,
risk
factors
leads
to
diagnostic
delay
therefore
lower
survival
rate.
Risk
factors,
which
include
drinking
alcohol,
smoking,
HPV
infection,
pro-inflammatory
factor-rich
diet,
poor
hygiene,
must
be
avoided
by
general
population.
Regular
clinical
examinations
should
enriched
an
search
protocol
for
summarized
this
review.
Moreover,
new
methods,
some
already
available
(vital
tissue
staining,
optical
imaging,
cytology,
salivary
biomarkers,
artificial
intelligence,
colposcopy,
spectroscopy),
newly
researched
techniques
increase
likelihood
stopping
pathological
process
at
stage.
Well-established
treatments
(surgery,
radiotherapy,
chemotherapy,
immunotherapy)
continuously
being
developed
using
novel
technologies,
increasing
their
success
Additionally,
researched.
This
review
presents
glance
cancer—its
current
classification
epidemiology—and
will
provide
insights
into
development
methods
therapies.
BMC Oral Health,
Journal Year:
2025,
Volume and Issue:
25(1)
Published: Jan. 24, 2025
To
evaluate
the
prognostic
role
of
preoperative
pan-immune-inflammation
value
(PIV)
index
in
patients
with
oral
squamous
cell
carcinoma
(OSCC)
after
undergoing
radical
resection
and
to
develop
a
prediction
model
for
these
patients.
A
large
cohort
study
was
conducted
between
January
2015
March
2022.
Univariate
multivariate
Cox
regression
used
assess
PIV,
propensity
score
matching
(PSM)
analysis
adjust
potential
confounders.
Randomized
survival
forest
(RSF)
relative
importance
PIV
prediction.
Finally,
Nomogram
plotted
predict
prognosis
cancer
total
779
were
enrolled
followed
up
(mean
follow-up
time
34.14
±
24.39).
High
significantly
associated
worse
OSCC
(hazard
ratio
[HR]
=
1.62,
95%
confidence
interval
[CI]:
1.15-2.29,
P
0.006).
The
same
trend
observed
PSM
(HR
1.55,95%
CI:
1.03-2.23,
0.035).
RSF
showed
that
ranked
third
ranking
all
factors.
calibration
curves
indicated
superior
predicting
1-,
3-,
5-year
is
an
independent
predictor
carcinoma,
column-line
graphical
based
on
can
effectively
prognosis.
Sensors,
Journal Year:
2025,
Volume and Issue:
25(5), P. 1459 - 1459
Published: Feb. 27, 2025
Oral
cancer
continues
to
cause
profound
suffering
and
is
associated
with
high
mortality
rates.
Early
detection
techniques
are
crucial
in
enhancing
patient
outcomes.
This
review
paper
thoroughly
evaluates
the
significance
of
biomarkers
recent
advancements
oral
detection,
emphasizing
cutting-edge
electrochemical
methods.
The
provides
an
epidemiological
etiological
overview,
outlining
its
clinical
importance
reviewing
current
state
art
Despite
considerable
progress,
conventional
methods
exhibit
limitations
such
as
invasiveness,
long
wait
times,
a
lack
accuracy,
creating
critical
need
for
more
robust
technologies.
emphasizes
biomarkers,
which
considered
promising
cues
early
facilitating
development
innovative
biosensing
seeks
illuminate
advances
precision
diagnostics,
along
usage
artificial
intelligence
strategies,
ultimately
contributing
significant
progress
battle
against
cancer.
