A flexible immunosensor based on the electrochemically rGO with Au SAM using half-antibody for collagen type I sensing DOI Creative Commons
Marcin Gwiazda, Ajeet Kaushik, Adrian Chlanda

et al.

Applied Surface Science Advances, Journal Year: 2022, Volume and Issue: 9, P. 100258 - 100258

Published: May 16, 2022

For an efficient diagnostic, modern biosensing systems require miniaturization of portable electronic devices, should be high sensitivity to achieve detection at a low level, specificity the targeted molecule, and ease operation. To address some such tasks, this research demonstrates fabrication electrochemically reduced graphene oxide (ERGO) on surface flexible, polymer-coated (polyethylene terephthalate, PET) covered with indium tin (ITO) for application. Such fabricated ERGO film exhibited electrical properties considerable amount groups followed by thiol functionalization (tERGO). High stability immobilization antibody receptors were achieved covalent interactions between deposited gold nanoparticles (AuNPs) half-IgG collagen type I antibodies. Our immunosensor revealed remarkable response complementary detected analyte in range 10 pg/mL 100 pg/mL. The performed had relatively limit (LOD = 6 pg/mL) comparison currently applied that are used collagen. Therefore, it is presented innovative attempt involving ideas future pliable immunosensors selectivity properties, which due user-friendly handling cost its production, enabling application wearable sensors.

Language: Английский

Artificial Intelligence (AI) and Internet of Medical Things (IoMT) Assisted Biomedical Systems for Intelligent Healthcare DOI Creative Commons
Pandiaraj Manickam, Siva Ananth Mariappan,

Sindhu Monica Murugesan

et al.

Biosensors, Journal Year: 2022, Volume and Issue: 12(8), P. 562 - 562

Published: July 25, 2022

Artificial intelligence (AI) is a modern approach based on computer science that develops programs and algorithms to make devices intelligent efficient for performing tasks usually require skilled human intelligence. AI involves various subsets, including machine learning (ML), deep (DL), conventional neural networks, fuzzy logic, speech recognition, with unique capabilities functionalities can improve the performances of medical sciences. Such systems simplify intervention in clinical diagnosis, imaging, decision-making ability. In same era, Internet Medical Things (IoMT) emerges as next-generation bio-analytical tool combines network-linked biomedical software application advancing health. this review, we discuss importance improving IoMT point-of-care (POC) used advanced healthcare sectors such cardiac measurement, cancer diabetes management. The role supporting robotic surgeries developed applications also discussed article. position functionality, detection accuracy, ability devices, evaluation associated risks assessment carefully critically review. This review encompasses technological engineering challenges prospects AI-based cloud-integrated personalized designing POC suitable healthcare.

Language: Английский

Citations

373

Recent advances in electrochemical biosensors – A brief review DOI Creative Commons

M.S. Sumitha,

T.S. Xavier

Hybrid Advances, Journal Year: 2023, Volume and Issue: 2, P. 100023 - 100023

Published: Jan. 25, 2023

A sensitive biological system and a detector with appropriate transducers for obtaining the output signals make up biosensor. These devices have wide range of uses, including disease screening, detection environmental pollutants, agriculture, routine medical examinations. The product's selectivity, sensitivity, stability, lower production costs will all be critical factors in its widespread commercialisation. Recently, scientists tackled issue developing nano biosensor high degree sensitivity selectivity recognition biomarkers immune responses cancer. fact that electrochemical biosensors may successfully employed detecting medications addition to pathogen has significantly altered COVID picture our favour. During worldwide epidemic, number cutting-edge SARS - CoV-2 portable, smartphone-connected instant were helpful. This article provides concise summary underlying working principle, generations developments numerous methods by biosensors. difficulties, knowledge gaps, possible solutions field are discussed context this categorisation. novel overview also sheds light on different kinds tasks they perform, as well recent “smart biosensor” industry potential future directions challenges growing subject.

Language: Английский

Citations

108

Nanosensors: Recent perspectives on attainments and future promise of downstream applications DOI
Tijjani Adam, Subash C. B. Gopinath

Process Biochemistry, Journal Year: 2022, Volume and Issue: 117, P. 153 - 173

Published: March 29, 2022

Language: Английский

Citations

72

Employing nano-enabled artificial intelligence (AI)-based smart technologies for prediction, screening, and detection of cancer DOI
Vibhas Chugh, Adreeja Basu, Ajeet Kaushik

et al.

Nanoscale, Journal Year: 2024, Volume and Issue: 16(11), P. 5458 - 5486

Published: Jan. 1, 2024

AI enabled imaging technology advances the precision, early detection, and personalizes treatment through analysis interpretation of medical images.

Language: Английский

Citations

24

Polydopamine films: Electrochemical growth and sensing applications DOI Creative Commons
Jakub Szewczyk, Daniel Aguilar‐Ferrer, Emerson Coy

et al.

European Polymer Journal, Journal Year: 2022, Volume and Issue: 174, P. 111346 - 111346

Published: June 10, 2022

Polydopamine is one of the most promising biomimetic polymers for environmental, biomedical and energy applications. This review presents current state art in electrochemistry polydopamine nanomaterials its applications electrochemical analysis sensing field. First, mechanism oxidation dopamine given concerning influence electrodeposition method processing conditions, e.g. pH value presented, as well particularities electro impedance spectroscopy studies. The formation free-standing thin films also discussed. Moreover, literature examples construction or functionalization sensors drug traces, disease markers pesticide contaminants detecting, potentiometric sensing, wearable strain are presented. Finally, we outline future developments perspectives

Language: Английский

Citations

67

Recent Advances in Electrochemical Biosensors for the Detection of Salmonellosis: Current Prospective and Challenges DOI Creative Commons

Subhasis Mahari,

Sonu Gandhi

Biosensors, Journal Year: 2022, Volume and Issue: 12(6), P. 365 - 365

Published: May 26, 2022

Salmonellosis is a major cause of foodborne infections, caused by Salmonella, posing health risk. It possesses the ability to infiltrate food supply chain at any point throughout manufacturing, distribution, processing or quality control process. Salmonella infection has increased severely and requires effective efficient methods for early monitoring detection. Traditional methods, such as real-time polymerase reaction culture plate, consume lot time are labor-intensive. Therefore, new quick detection on-field applications urgently needed. Biosensors provide consumer-friendly approaches diagnoses. In last few years, there been surge in research into creation reliable advanced electrochemical sensors strains samples. Electrochemical extensive accuracy reproducible results. Herein, we present comprehensive overview focusing on various mechanisms transducer. Further, explain new-generation biosensors (microfluidics, CRISPR- IOT-based) point-of care applications. This review also highlights limitations developing future possibilities.

Language: Английский

Citations

55

Multifunctional carbon nanomaterials decorated molecularly imprinted hybrid polymers for efficient electrochemical antibiotics sensing DOI
Ayushi Singhal, Mohd. Abubakar Sadique, Neeraj Kumar

et al.

Journal of environmental chemical engineering, Journal Year: 2022, Volume and Issue: 10(3), P. 107703 - 107703

Published: April 15, 2022

Language: Английский

Citations

42

Recent developments in electrochemical sensors based on graphene for bioanalytical applications DOI Creative Commons
Abdulazeez T. Lawal

Sensing and Bio-Sensing Research, Journal Year: 2023, Volume and Issue: 41, P. 100571 - 100571

Published: July 8, 2023

An effective and affordable technique for detecting a variety of substances biological, medical, environmental significance is electrochemical sensing (ECS). Due to their distinctive structures abilities offer robust electrocatalytic activity with little surface fouling, low cost, biocompatibility, simple electron transfer kinetics, carbon materials-based electrodes like graphene (GR) nanotube (CNT) are frequently used the development sensors. Since GR has large specific area, it can host number biomolecules still have decent detection sensitivity. Along important developments in synthesis, purification, conjugation, biofunctionalization GR, device integration technologies nanofabrication evolved. Combinations aforementioned characteristics accelerated GR-based sensors many critical bio-analyses. The rapid bioanalyses better sensitivity selectivity been facilitated by combination features. Direct transport between enzyme active electrode region made possible application GR. It easily construct execute on-site oxidases dehydrogenases improved thanks excellent electro-catalytic activities on redox reaction hydrogen peroxide (H2O2) nicotinamide adenine dinucleotides (NADH). GR's oxidation NADH, thiols, H2O2, other interfering species occurs at potentials, use effectively suppresses these species. two benefits clinical chemistry, food quality control, wastewater treatment, bioprocessing great resistance fouling selectivity.

Language: Английский

Citations

38

Electrochemical detection of dopamine using WSe2 microsheets modified platinum electrode DOI
Hassan A. Alhazmi, Mohd Imran, Shahzad Ahmed

et al.

Physica Scripta, Journal Year: 2023, Volume and Issue: 98(10), P. 105006 - 105006

Published: Aug. 15, 2023

Abstract Transition metal dichalcogenides (TMDs) have been proven to possess many properties that are beneficial for the application of electrochemical detection. In this study, tungsten diselenide (WSe 2 ) was synthesized utilizing hydrothermal method and used modify platinum electrode. The behaviour WSe -modified electrode examined cyclic voltammetry (CV) impedance spectroscopy (EIS) methods. displays a wide linear range 5–100 μ M with correlation coefficient 0.986. detection limit found be 5 M. has good stability dependency on scan rate.

Language: Английский

Citations

32

Nb4C3Tx MXene-AgNPs decorated laser-induced graphene for selective detection of dopamine DOI

Megha Shinde,

Sri Ramulu Torati,

Gymama Slaughter

et al.

Journal of Electroanalytical Chemistry, Journal Year: 2024, Volume and Issue: 959, P. 118180 - 118180

Published: March 12, 2024

Language: Английский

Citations

11