MXene-Based Functional Materials as Antibacterial and Antiviral Agents DOI

Sushma Thapa,

Kshitij RB Singh,

Arunadevi Natarajan

et al.

ACS symposium series, Journal Year: 2023, Volume and Issue: unknown, P. 363 - 394

Published: Dec. 13, 2023

MXene, a novel compound of two-dimensional (2D) metal carbides, nitrides, and carbonitrides, exhibit magnificent antimicrobial characteristics against pathogenic bacteria viruses owing to their versatile features like substantial chemical stability, huge specific surface area, large interlayer space, hydrophilic nature. Due the rise in drug resistance bacteria, necessity fabricate use innovative structures with high efficacy is most needed; therefore, research on effective agents microorganisms blooming. 2D MXene demonstrates excellent properties viruses. Therefore, this book chapter briefly summarizes preparation process its characteristics. In end, promising utilization for activities future perspectives are discussed.

Language: Английский

Impact of nanotechnology on conventional and artificial intelligence-based biosensing strategies for the detection of viruses DOI Creative Commons
Murugan Ramalingam,

Abinaya Jaisankar,

Lijia Cheng

et al.

Discover Nano, Journal Year: 2023, Volume and Issue: 18(1)

Published: April 1, 2023

Abstract Recent years have witnessed the emergence of several viruses and other pathogens. Some these infectious diseases spread globally, resulting in pandemics. Although biosensors various types been utilized for virus detection, their limited sensitivity remains an issue. Therefore, development better diagnostic tools that facilitate more efficient detection pathogens has become important. Nanotechnology recognized as a powerful tool viruses, it is expected to change landscape analysis. Recently, nanomaterials gained enormous attention value improving biosensor performance owing high surface-to-volume ratio quantum size effects. This article reviews impact nanotechnology on design, development, sensors viruses. Special paid nanoscale materials, nanobiosensors, internet medical things, artificial intelligence-based viral techniques.

Language: Английский

Citations

28

Importance of Nano-Sized Feed Additives in Animal Nutrition DOI Open Access
Büşra Dumlu

Journal of Agricultural Production, Journal Year: 2024, Volume and Issue: 5(1), P. 55 - 72

Published: March 31, 2024

"Nano", which derives from the Latin word nanus and means dwarf, refers to a very small unit of measurement equal one billionth meter. Nanotechnology, deals with manipulation matter at atomic molecular level, has an application area in animal husbandry as well many fields. Nano-sized feed additives, have come forefront livestock sector recent years, become innovative used increase nutritional value feeds optimize health performance. Since these additives are nano-sized particles increased specific surface area, they can positive effect on number factors such digestibility, nutrient absorption, immune system, growth development. Minerals form nanoparticles bioavailability by passing through intestinal wall body cells faster compared larger particles. The nano level substance not only increases productivity animals, but also brings potential improve functionality molecules. Nano digestion absorption feed, allowing animals benefit more effectively. However, there several challenges associated this approach. These include for endotoxin production, reduced due interaction natural nutrients, possibility nanoparticle accumulation body, risks, ethical considerations, environmental concerns some negative effects interference nutrients that be avoided encapsulation. This article discusses studies offer benefits nutrition.

Language: Английский

Citations

8

A Rapid Label-Free Disposable Electrochemical Salivary Point-of-Care Sensor for SARS-CoV-2 Detection and Quantification DOI Creative Commons
Nadia Farsaeivahid,

Christian Grenier,

Sheyda Nazarian

et al.

Sensors, Journal Year: 2022, Volume and Issue: 23(1), P. 433 - 433

Published: Dec. 30, 2022

The coronavirus disease 2019 (COVID-19) pandemic has created an urgent need for accurate early diagnosis and monitoring. A label-free rapid electrochemical point-of-care (POC) biosensor SARS-CoV-2 detection in human saliva is reported here to help address the shortcomings of traditional nucleic acid amplification methods give a quantitative assessment viral load track infection status anywhere, using disposable sensor chips. new chemical construct gold nanoparticles (GNp) thionine (Th) are immobilized on carboxylic functionalized carbon nanotubes (SWCNT-COOH) high-performance biosensing. uses with one-step pretreatment simple testing procedure as analytical medium due user-friendly non-invasive nature its procurement from patients. response time 5 min limit (LOD) reaching 200 500 pM freely suspended spike (S) protein phosphate buffer saline (PBS) saliva, respectively. sensor's performance was also proven detecting COVID-19 pseudovirus electrolyte solution LOD 10

Language: Английский

Citations

26

Recent Advances of Representative Optical Biosensors for Rapid and Sensitive Diagnostics of SARS-CoV-2 DOI Creative Commons
Meimei Xu, Yanyan Li, Chenglong Lin

et al.

Biosensors, Journal Year: 2022, Volume and Issue: 12(10), P. 862 - 862

Published: Oct. 12, 2022

The outbreak of Corona Virus Disease 2019 (COVID-19) has again emphasized the significance developing rapid and highly sensitive testing tools for quickly identifying infected patients. Although current reverse transcription polymerase chain reaction (RT-PCR) diagnostic techniques can satisfy required sensitivity specificity, inherent disadvantages with time-consuming, sophisticated equipment professional operators limit its application scopes. Compared traditional detection techniques, optical biosensors based on nanomaterials/nanostructures have received much interest in SARS-CoV-2 due to high sensitivity, accuracy, fast response. In this review, research progress diagnosis, including fluorescence biosensors, colorimetric Surface Enhancement Raman Scattering (SERS) Plasmon Resonance (SPR) was comprehensively summarized. Further, promising strategies improve are also explained. Optical not only realize but be applied judge infectiousness virus guide choice vaccines, showing enormous potential become point-of-care timely control pandemic.

Language: Английский

Citations

25

Biomimetic nanoplasmonic sensor for rapid evaluation of neutralizing SARS-CoV-2 monoclonal antibodies as antiviral therapy DOI Creative Commons
Razia Batool, Maria Soler, Francesca Colavita

et al.

Biosensors and Bioelectronics, Journal Year: 2023, Volume and Issue: 226, P. 115137 - 115137

Published: Feb. 7, 2023

Monoclonal antibody (mAb) therapy is one of the most promising immunotherapies that have shown potential to prevent or neutralize effects COVID-19 in patients at very early stages, with a few formulations recently approved by European and American medicine agencies. However, main bottleneck for their general implementation resides time-consuming, laborious, highly-specialized techniques employed manufacturing assessing these therapies, excessively increasing prices delaying administration patients. We propose biomimetic nanoplasmonic biosensor as novel analytical technique screening evaluation mAb therapies simpler, faster, reliable manner. By creating an artificial cell membrane on plasmonic sensor surface, our label-free sensing approach enables real-time monitoring virus-cell interactions well direct analysis blocking only 15 min assay time. achieved detection limits 10

Language: Английский

Citations

15

Optical characteristics and biosensing application of core@shell nanomaterials DOI Creative Commons

Sarita Shaktawat,

Kshitij RB Singh,

Sushma Thapa

et al.

Materials Letters X, Journal Year: 2023, Volume and Issue: 17, P. 100187 - 100187

Published: Feb. 28, 2023

[email protected] nanomaterials are a class of materials containing core and shell, both at the nanometer scale, as they have become consequential research interest owing to their optical, electrical, magnetic properties. Moreover, various also emerged in many other fields, such catalysis, pharmaceuticals, biomedical due less toxicity, surface area, good biocompatibility, adequate penetration power for biological tissue, selectivity target molecules. Hence, this review covers optical properties biosensors based on nanomaterials, example, ([email protected]), (CeO2@polyaniline), protected]anic (poly(vinylidene difluoride)@dopamine) applications; along with this, it discusses advantage disadvantage nanomaterials.

Language: Английский

Citations

9

MXenes‐based Biosensors DOI

Sushma Thapa,

Kshitij RB Singh,

Arunadevi Natarajan

et al.

Published: March 29, 2024

MXenes are recently developed two-dimensional ( 2D ) inorganic compounds with few atomic layers that have exceptional properties, for instance, thermal, magnetic, optical, electronic, and mechanical. Owing to their excellent chemical composition, layered structure, MXene is one of the prime materials advancement biosensors, among other latest nanomaterials. Fabricating advanced biosensors high selectivity sensitivity most required concerns in biosensors. Numerous nanomaterials, including MXenes, been introduced fabricate obtaining sensitivity. Therefore, this book chapter, were discussed based on biomedical, agricultural, environmental remediation applications.

Language: Английский

Citations

2

Introduction to smart and intelligent nanomaterials for biosensors DOI

Arunadevi Natarajan,

Kshitij RB Singh, Harshita Rai

et al.

Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 17

Published: Nov. 29, 2024

Language: Английский

Citations

2

Emerging Multiplex Nucleic Acid Diagnostic Tests for Combating COVID-19 DOI Creative Commons
Patarajarin Akarapipad, Elizabeth Bertelson, Alexander F. Pessell

et al.

Biosensors, Journal Year: 2022, Volume and Issue: 12(11), P. 978 - 978

Published: Nov. 7, 2022

The COVID-19 pandemic caused by SARS-CoV-2 has drawn attention to the need for fast and accurate diagnostic testing. Concerns from emerging variants other circulating respiratory viral pathogens further underscore importance of expanding testing multiplex detection, as single-plex may fail detect viruses, while sequencing can be too slow expensive a tool. As result, there have been significant advances in nucleic-acid-based virus testing, creating timely review. This review first introduces frequent nucleic acid targets tests, then proceeds comprehensive up-to-date overview assays that incorporate various detection reactions readout modalities. performances, advantages, disadvantages these are discussed, followed highlights platforms amenable point-of-care use. Finally, this points out remaining technical challenges shares perspectives on future research development. By examining state art synthesizing existing development provide useful resource facilitating ultimately combating COVID-19.

Language: Английский

Citations

10

Immunochromatographic enhancement strategy for SARS-CoV-2 detection based on nanotechnology DOI

Qingwen Sun,

Qihong Ning,

Tangan Li

et al.

Nanoscale, Journal Year: 2023, Volume and Issue: 15(37), P. 15092 - 15107

Published: Jan. 1, 2023

This review summarizes new methods for improving the sensitivity of immunochromatographic SARS-CoV-2 detection based on nanotechnology.

Language: Английский

Citations

4