Motor threshold, motor evoked potential, central motor conduction time DOI
Sein Schmidt, Stephan A. Brandt

Oxford University Press eBooks, Journal Year: 2021, Volume and Issue: unknown, P. 301 - 328

Published: July 14, 2021

Abstract In this chapter, we survey parameters influencing the assessment of size and latency motor evoked potentials (MEP), in normal pathological conditions, methods to allow for a meaningful quantification MEP characteristics. line with first edition textbook, extensively discuss three established mechanisms intrinsic physiological variance collision techniques that aim minimize their influence. For time, ever wider use optical navigation targeting systems brain stimulation, novel capture influence extrinsic biophysical variance. Together, following rules laid out transcranial magnetic stimulation (TMS) can account spinal advance investigations central origins variability.

Language: Английский

State-dependent effectiveness of cathodal transcranial direct current stimulation on cortical excitability DOI Creative Commons
Alessandra Vergallito, Erica Varoli, Alberto Pisoni

et al.

NeuroImage, Journal Year: 2023, Volume and Issue: 277, P. 120242 - 120242

Published: June 21, 2023

The extensive use of transcranial direct current stimulation (tDCS) in experimental and clinical settings does not correspond to an in-depth understanding its underlying neurophysiological mechanisms. In previous studies, we employed integrated system Transcranial Magnetic Stimulation Electroencephalography (TMS-EEG) track the effect tDCS on cortical excitability. At rest, anodal (a-tDCS) over right Posterior Parietal Cortex (rPPC) elicits a widespread increase contrast, cathodal (c-tDCS) fails modulate excitability, being indistinguishable from sham stimulation. Here investigated whether endogenous task-induced activation during might change this pattern, improving c-tDCS effectiveness modulating Experiment 1, tested performance Visuospatial Working Memory Task (VWMT) modified Posner Cueing (mPCT), involving rPPC, could be modulated by c-tDCS. Thirty-eight participants were involved two-session experiment receiving either or tasks execution. 2, recruited sixteen novel who performed same paradigm but underwent TMS-EEG recordings pre- 10 min post- Behavioral results showed that significantly mPCT compared sham. level, reduced excitability frontoparietal network likely task Taken together, our provide evidence state dependence effectively. conceptual applicative implications are discussed.

Language: Английский

Citations

17
A Roadmap for Transformative Translational Research on Gambling Disorder in the UK Funded by A New Levy on The Gambling Industry DOI Creative Commons
Tristan Hynes, Henrietta Bowden‐Jones, Samuel R. Chamberlain

et al.

Neuroscience & Biobehavioral Reviews, Journal Year: 2025, Volume and Issue: unknown, P. 106071 - 106071

Published: Feb. 1, 2025

Language: Английский

Citations

0
Beyond the Surface: Deep TMS Efficacy in Reducing Craving in Addictive Disorders. A Systematic Review and Meta-analysis. DOI Creative Commons
Lilia Del Mauro,

Alessandra Vergallito,

Francantonio Devoto

et al.

Biological Psychiatry Cognitive Neuroscience and Neuroimaging, Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

Substance use disorders (SUDs) and Gambling Disorder (GD) are addictive diseases with a chronic course. Due to the limited efficacy of conventional treatments, there is growing interest in alternative approaches targeting altered neural circuits underlying these disorders. Deep Transcranial Magnetic Stimulation (dTMS) has emerged as promising neuromodulation technique capable reaching deep bilateral brain regions. However, no definite recommendation for its addiction treatment exists. This study systematically reviewed quantitatively analyzed dTMS effects SUDs GD. Following PRISMA guidelines, we screened four electronic databases up February 2024 selected relevant English-written original research articles. Seventeen papers were included systematic review. As only minority studies employed sham-controlled design, ran meta-analysis on subset 12 studies, computing pre-post real stimulation standardized mean change (SMCC) effect size, using self-reported craving scores dependent variable. The results showed significant large reducing (SMCC = - 1.26, 95% CI [-1.67, 0.86], p <.001). High heterogeneity across was found at both quantitative qualitative levels. Results provide preliminary evidence supporting effectiveness treatment. Current limitations future directions critically discussed, highlighting need further rigorous refine therapeutic potential develop consensus-based guidelines clinical application.

Language: Английский

Citations

0
Neuromodulation of dorsal and ventral prefrontal cortex during gambling task performance in low and high impulsive individuals DOI Creative Commons
Elena Gomis‐Vicent, John Turner, Michael A. Nitsche

et al.

Addictive Behaviors, Journal Year: 2025, Volume and Issue: 167, P. 108358 - 108358

Published: April 12, 2025

Language: Английский

Citations

0
Treating Gambling Disorder Using Repetitive Transcranial Magnetic Stimulation with Symptom Provocation DOI Creative Commons

C. Jou,

Xin Yu,

Galen Chin Lun Hung

et al.

Transcranial magnetic stimulation ., Journal Year: 2025, Volume and Issue: unknown, P. 100099 - 100099

Published: April 1, 2025

Language: Английский

Citations

0
Transcranial Magnetic Stimulation for the Treatment of Gambling Disorder: A Systematic Review DOI Creative Commons
Carmen Concerto, Maria Salvina Signorelli, Cecilia Chiarenza

et al.

Journal of Integrative Neuroscience, Journal Year: 2023, Volume and Issue: 22(6), P. 164 - 164

Published: Nov. 21, 2023

Gambling Disorder (GD) is a behavioral addiction listed within the diagnostic category of substance-related and addictive disorders. Recently, transcranial magnetic stimulation (TMS), which non-invasively stimulates brain has neuromodulatory properties, emerged as an innovative treatment tool for GD, thus offering new option management this complex disorder. The present review explored efficacy TMS possible non-pharmacological GD.

Language: Английский

Citations

4
Beyond the Surface: Deep TMS Efficacy in Reducing Craving in Addictive Disorders. A Systematic Review and Meta-analysis DOI Creative Commons
Lilia Del Mauro,

Alessandra Vergallito,

Francantonio Devoto

et al.

medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 13, 2024

ABSTRACT Background Substance use disorders (SUDs) and Gambling Disorder (GD) are addictive with a chronic course. Given the limited efficacy of conventional treatments, there is increasing interest in alternative strategies targeting altered neural circuits associated disease. In this context, deep Transcranial Magnetic Stimulation (dTMS) has emerged as novel neuromodulation technique capable reaching brain regions. However, no definite recommendation for its addiction treatment exists. This study systematically reviewed quantitatively analyzed dTMS effects SUDs GD populations. Methods Following PRISMA guidelines, we screened four electronic databases up to February 2024 selected relevant English-written original research articles. 17 papers were included systematic review. As only minority studies employed sham-controlled design, ran meta-analysis on subset 12 studies, computing pre-post real stimulation standardized mean change (SMCC) effect size, using self-reported craving scores dependent variable. Results The results showed significant large active reducing (SMCC = - 1.26, 95% CI [-1.67, 0.86], p <.001). High heterogeneity at both quantitative qualitative levels across was found, focusing different types one gambling behaviors. Conclusions provide initial evidence feasibility care. further comprehensive needed unveil several methodological challenges. limitations available literature future directions critically discussed.

Language: Английский

Citations

1
Brain Sciences Special Issue “Neuromodulation of Cortical Networks in Neurological and Neuropsychiatric Disorders: Potential Clinical Indications and the Biophysiological Impact of Stimulation” DOI Creative Commons
Maja Rogić Vidaković, Joško Šoda,

Joshua Kuluva

et al.

Brain Sciences, Journal Year: 2024, Volume and Issue: 14(5), P. 459 - 459

Published: May 1, 2024

Individuals with neurological and neuropsychiatric disorders face a variety of difficulties that can significantly impact their daily lives [...]

Language: Английский

Citations

0
Boosting Psychotherapy With Noninvasive Brain Stimulation: The Whys and Wherefores of Modulating Neural Plasticity to Promote Therapeutic Change DOI Creative Commons
Daniele Saccenti, Leonor J. Romero Lauro, Sofia Crespi

et al.

Neural Plasticity, Journal Year: 2024, Volume and Issue: 2024(1)

Published: Jan. 1, 2024

The phenomenon of neural plasticity pertains to the intrinsic capacity neurons undergo structural and functional reconfiguration through learning experiential interaction with environment. These changes could manifest themselves not only as a consequence various life experiences but also following therapeutic interventions, including application noninvasive brain stimulation (NIBS) psychotherapy. As standalone therapies, both NIBS psychotherapy have demonstrated their efficacy in amelioration psychiatric disorders’ symptoms, certain variability terms effect sizes duration. Consequently, scholars suggested convenience integrating two interventions into multimodal treatment boost prolong outcomes. Such an approach is still its infancy, physiological underpinnings substantiating effectiveness utility combined are be clarified. Therefore, this opinion paper aims provide theoretical framework consisting compelling arguments why adding can promote change. Namely, we will discuss effects thus providing rationale explain potential advantages approach.

Language: Английский

Citations

0
Motor threshold, motor evoked potential, central motor conduction time DOI
Sein Schmidt, Stephan A. Brandt

Oxford University Press eBooks, Journal Year: 2021, Volume and Issue: unknown, P. 301 - 328

Published: July 14, 2021

Abstract In this chapter, we survey parameters influencing the assessment of size and latency motor evoked potentials (MEP), in normal pathological conditions, methods to allow for a meaningful quantification MEP characteristics. line with first edition textbook, extensively discuss three established mechanisms intrinsic physiological variance collision techniques that aim minimize their influence. For time, ever wider use optical navigation targeting systems brain stimulation, novel capture influence extrinsic biophysical variance. Together, following rules laid out transcranial magnetic stimulation (TMS) can account spinal advance investigations central origins variability.

Language: Английский

Citations

1