Dose-Escalated Preoperative Proton Therapy for Retroperitoneal Sarcomas: Initial Outcomes of a New Treatment Paradigm DOI Creative Commons
Sreenija Yarlagadda, Tuğçe Kütük, Ramon E. Jimenez

et al.

Advances in Radiation Oncology, Journal Year: 2023, Volume and Issue: 9(4), P. 101431 - 101431

Published: Dec. 30, 2023

Retroperitoneal sarcomas (RPS) have varied treatment practices with regard to the use of radiation therapy (RT). Preoperative RT ∼50 Gy is commonly used, but Surgery With or Without Radiation Therapy in Untreated Nonmetastatic Sarcoma (STRASS-1) randomized trial demonstrated no improvement abdominal recurrence-free survival preoperative RT. Dose escalation has been proposed improve efficacy We analyzed RPS treated intensity modulated proton (IMPT) an escalated dose 63 at a single institution.

Language: Английский

The Role of Surgery in Oligometastatic Retroperitoneal Sarcoma DOI Creative Commons
Lindsay A. Janes, Christina V. Angeles

Current Oncology, Journal Year: 2023, Volume and Issue: 30(6), P. 5240 - 5250

Published: May 24, 2023

Retroperitoneal sarcomas are extremely rare, comprising <15% of primary sarcomas. Distant metastasis occurs in about 20% cases, with pulmonary and hepatic as the most common sites hematogenous spread. Although surgical resection is well established main treatment localized disease, there limited guidelines for intra-abdominal distant metastases. There inadequate systemic options patients metastatic sarcoma, thereby necessitating consideration carefully selected patients. Key points to consider include tumor biology, patient fitness co-morbidities, overall prognosis, goals care. Multidisciplinary sarcoma board discussion each case an essential practice order deliver best care these The purpose this review summarize published literature on past present role surgery oligometastatic retroperitoneal inform management difficult disease.

Language: Английский

Citations

1
Does compartmental resection really impact retroperitoneal soft tissue sarcomas? A retrospective analysis from a Single Referral Center DOI
Dorian Yarih García-Ortega,

José Antonio Ortega Jiménez,

Ana Paulina Melendez-Fernandez

et al.

Surgical Oncology, Journal Year: 2023, Volume and Issue: 51, P. 101997 - 101997

Published: Sept. 27, 2023

Language: Английский

Citations

1
The surgical treatment of female primary pelvic retroperitoneal tumours: A retrospective study of 99 patients from a single centre in China DOI
Xueyan Liu,

Mengling Zhao,

Hanlin Fu

et al.

International Journal of Medical Robotics and Computer Assisted Surgery, Journal Year: 2023, Volume and Issue: 20(1)

Published: Oct. 30, 2023

To summarise the application of minimally invasive surgery for female primary pelvic retroperitoneal tumours (PPRTs).The clinical data PPRT in a hospital between January 2017 and August 2022 were retrospectively collected. Surgical outcomes cystic solid two techniques compared.99 patients included. Cystic had fewer intraoperative injuries (4.0% vs. 28.0%, p < 0.001) than tumours. Robot-assisted laparoscopy (RALS) seemed to have complications (8.3% 35.1%, = 0.156) conventional (CLS) For tumours, RALS included larger tumour sizes longer operative times (p 0.05), but injury was comparable CLS. exhibited higher cost CLS all tumours.Minimally PPRTs tends be more difficult has slight advantage over with respect short-term outcomes.

Language: Английский

Citations

1
A Case of Cystic Retroperitoneal Dedifferentiated Liposarcoma Diagnosed by Percutaneous Image-Guided Biopsy DOI Creative Commons

Kaede Morihara,

Takahito Negishi, Nobuki Furubayashi

et al.

Case Reports in Oncology, Journal Year: 2023, Volume and Issue: 16(1), P. 1460 - 1465

Published: Nov. 24, 2023

Dedifferentiated liposarcoma (DDLP) was initially defined as a tumor containing differentiated and distinct regions of nonlipogenic spindle cell or pleomorphic sarcoma. Retroperitoneal liposarcomas feature characteristic appearance with predominantly fatty component, cystic are rare. We describe case retroperitoneal DDLP consisting multilocular cysts.A 77-year-old man previously visited doctor because an echo scan unexpectedly revealed abdominal tumor. Contrast computed tomography (CT) disclosed large spanning from the left upper abdomen to retroperitoneum, poorly marginated soft tissue structures were present around aorta, inferior vena cava, pancreas, mesentery, kidney. CT also right lung mass. The in mass strongly enhanced on 2-deoxy-2-[fluorine-18] fluoro-d-glucose positron emission tomography, suggesting malignant metastasis. CT-guided percutaneous biopsy targeting perirenal structure performed, diagnosed DDLP. Lung metastasis present, surrounded multiple organs. Therefore, not suitable for surgical resection but it indicated chemotherapy based multidisciplinary discussion.We experienced by image-guided treated appropriately pathological diagnosis.

Language: Английский

Citations

1
Dose-Escalated Preoperative Proton Therapy for Retroperitoneal Sarcomas: Initial Outcomes of a New Treatment Paradigm DOI Creative Commons
Sreenija Yarlagadda, Tuğçe Kütük, Ramon E. Jimenez

et al.

Advances in Radiation Oncology, Journal Year: 2023, Volume and Issue: 9(4), P. 101431 - 101431

Published: Dec. 30, 2023

Retroperitoneal sarcomas (RPS) have varied treatment practices with regard to the use of radiation therapy (RT). Preoperative RT ∼50 Gy is commonly used, but Surgery With or Without Radiation Therapy in Untreated Nonmetastatic Sarcoma (STRASS-1) randomized trial demonstrated no improvement abdominal recurrence-free survival preoperative RT. Dose escalation has been proposed improve efficacy We analyzed RPS treated intensity modulated proton (IMPT) an escalated dose 63 at a single institution.

Language: Английский

Citations

1