Respiratory Diseases with High Occupational Fraction in Italy: Results from the Italian Hospital Discharge Registry (2010–2021) DOI Open Access
Pierpaolo Ferrante

Healthcare, Journal Year: 2024, Volume and Issue: 12(24), P. 2565 - 2565

Published: Dec. 20, 2024

Objectives: Occupational respiratory diseases represent a major public health concern worldwide. This study analyses the hospitalization costs and characteristics of four occupational diseases: malignant mesothelioma (MM), sinonasal cancer (SNC), pneumoconiosis (PN), hypersensitivity pneumonitis (HP). The findings are situated within context Italy’s population trends healthcare system, offering insights into economic clinical burden these diseases. Study Design: retrospective, population-based examines Italian hospitalizations for MM, SNC, PN, HP during period 2010–2021. primary outcomes were number hospitalizations, length stay, associated cost. Costs derived from charges linked to diagnosis-related groups (version 24) diagnostic category coding systems. Results: Though is rapidly aging, annual rate declined by 35% over period. SNC aligned with overall trend, PN MM experienced faster declines, whereas admissions remained steady. emerged as most resource-intensive (EUR 25 million yearly, 86% attributable occupation), followed 10 million, entirely occupational), 5 EUR 650,000 2 370,000 occupational). All studied had an average stay exceeding national one. shortest (6.5 days) least expensive 3647). In contrast, mean days, admission averaging 4700 4000 HP. median age was highest (78 years) (71 years), while patients approximately 65 years. Conclusions: Consistent their anticipated benefits, workplace regulations last three decades, including 1992 asbestos ban D.lgs. 81/2008, significant reductions in increased at discharge PN. fewer conclusions can be drawn due lower fractions (10–20%). finding suggests adding exposure flag hospital records acknowledged enhance surveillance. Finally, this provides first estimate fraction Italy.

Language: Английский

European cancer mortality predictions for the year 2025 with focus on breast cancer DOI Creative Commons
Claudia Santucci, Silvia Mignozzi, Fabio Levi

et al.

Annals of Oncology, Journal Year: 2025, Volume and Issue: unknown

Published: March 1, 2025

Language: Английский

Citations

0
A 7-Year Active Surveillance Experience for Occupational Lung Cancer in Bologna, Italy (2017-2023) DOI

Monica Bogni,

Daniela Cervino,

Marta Rossi

et al.

˜La œMedicina del lavoro, Journal Year: 2025, Volume and Issue: 116(2), P. 16173 - 16173

Published: April 17, 2025

Background: In Italy, lung cancer is the second most frequent neoplasm in men and third women. Exposure to carcinogens workplaces plays a significant role. Still, cases attributable occupational exposure are currently under-reported as diseases: current National Prevention Plan also encourages active research projects for detection of cancers exposure. Methods: The Unit Safety Workplace Bologna Local Health Authority (Azienda Unità Sanitaria Locale-AUSL-)created network surveillance with dedicated Diagnostic Therapeutic Care Pathways(PDTA). Possible were selected within all incident PDTA using self-completed patient filter form. Only patients through form interviewed; physicians collected personal, occupational, clinical history. Definition cooperation system local office Institute Insurance(INAIL)for monitoring process during medico-legal assessments conducted by insurance institute up resolution. Results: 453 completed form, 177 had potential Of these, 140 accepted direct interview physicians. One hundred eleven interviewed assessed sure or suspect origin: 82, claim recognition was sent INAIL, while other 29 INAIL report epidemiological purposes. Out 82 compensation claims, 18 individuals (4 females 14 males) received compensation, 4 remain under investigation. A total 53 claims rejected: 54.7% lack risk factors, 24.5% insufficient exposure, 9.4% due inadequate administrative documentation, 7.5% because 3.8% absence causal association. Conclusions: Several found that otherwise would have been unrecognized. Asbestos agent occurring widespread work sectors—construction manufacture metalworking products—and period from 1970 1980. Other relevant agents welding fumes polycyclic aromatic hydrocarbons. Active surveillance, interviews, integrated complementary essential increase rate.

Language: Английский

Citations

0
Gender Differences in Sinonasal Cancer Incidence: Data from the Italian Registry DOI Open Access
Alessandra Binazzi,

Davide Di Marzio,

Carolina Mensi

et al.

Cancers, Journal Year: 2024, Volume and Issue: 16(11), P. 2053 - 2053

Published: May 29, 2024

Although rare, sinonasal cancers (SNCs) have a high occupational attributable fraction. We applied gender-based approaches to descriptive analyses, incidence, and patterns of exposures using the Italian National Sinonasal Cancer Registry (ReNaTuNS: Registro Nazionale Tumori Naso-Sinusali). The study included 2851 SNC patients. was diagnosed more often in men (73%) than women (27%). most frequent morphology intestinal-type adenocarcinoma (33%), whereas women, it squamous cell carcinoma (49%). Nasal cavities were predominant both genders (50%), ethmoidal sinus (24%), maxillary (24%). Incidence rates 0.76 (per 100,000 person-years) 0.24 increased by age, evidently men, peaking over 75 years both. Occupational wood leather dusts (41% for 33% women). Few extra-occupational or domestic. Unlikely exposure relevant (57%). surveillance cases through registry that allows identification compensation this disease is important Italy, where numerous workers are exposed carcinogens SNC, without even being aware. Considering rarity disease, particularly among ReNaTuNS can provide method analyze gender differences.

Language: Английский

Citations

3
Cancers attributable to overweight and obesity in Italy DOI Creative Commons
Matteo Di Maso, Claudio Pelucchi, Giulia Collatuzzo

et al.

Cancer Epidemiology, Journal Year: 2023, Volume and Issue: 87, P. 102468 - 102468

Published: Oct. 11, 2023

Overweight and obesity are associated with multiple cancers. We quantified the burden of cancer attributable to overweight in Italy. estimated sex- site-specific population fractions (PAFs) combining relative risks (from recent meta-analyses) national prevalence data a large sample survey conducted 2005, account for 15-year lag period). Using nationwide mortality statistics registries data, we number cases deaths Italy 2020, based on counterfactual scenario body mass index < 25 kg/m2. 3.6% cancers men 4.0% women were obesity, corresponding, respectively, over 6900 7200 diagnoses 2020. Attributable 3600 2700 women. PAFs (attributable cases) were, 38.1% (215 21.8% (49 esophageal adenocarcinoma, 19.1% (1715 14.5% (585 liver, 18.7% (1692 16.7% (747 kidney, 13.7% (938 10.1% (749 pancreatic, 10.2% (2389 3.4% (690 colorectal In women, 22.3% (1859 endometrial 5.7% (2556 post-menopausal breast cancer. The is considerable, but smaller compared other high income countries, likely because lower Italian population.

Language: Английский

Citations

5
Fraction of cancers attributable to and prevented by reproductive factors and exogenous hormones use in Italy DOI
Federica Turati, Giulia Collatuzzo, Matteo Di Maso

et al.

European Journal of Obstetrics & Gynecology and Reproductive Biology, Journal Year: 2024, Volume and Issue: 301, P. 49 - 54

Published: July 5, 2024

Language: Английский

Citations

1
Cancers attributable to diet in Italy DOI Creative Commons
Federica Turati, Gianfranco Alicandro, Giulia Collatuzzo

et al.

International Journal of Cancer, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 24, 2024

Abstract Cancer burden can be reduced by controlling modifiable risk factors, including diet. We provided an evidence‐based assessment of cancer cases and deaths attributable to diet in Italy 2020. considered dietary factor‐cancer type pairs for which the World Research Fund/American Institute – Continuous Update Project reported either ‘convincing’ or ‘probable’ evidence causal association. Relative risks were retrieved from recent meta‐analyses intakes (around 2005) a national food consumption survey. Sex‐specific population fractions (PAFs) computed comparing distribution Italian against counterfactual scenarios based on recommendations. Using data mortality registries 2020, we estimated number deaths, assuming ~15‐year lag period. Unhealthy accounted 6.3% (95% CI: 2.5%–9.9%) all men 4.5% 1.7%–7.4%) women. PAFs colorectal 10.5% 7.0% any intake processed meat, 3.3% 2.0% high red 4.8% 4.3% low dairy products, 7.9% 9.0% fiber women, respectively. non‐starchy vegetables fruit ranged 0.8% 16.5% 0.6%–17.8% women cancers aerodigestive tract. The associated with unfavorable habits is considerable, but appears lower than other high‐income countries, reflecting typically Mediterranean

Language: Английский

Citations

0
Respiratory Diseases with High Occupational Fraction in Italy: Results from the Italian Hospital Discharge Registry (2010–2021) DOI Open Access
Pierpaolo Ferrante

Healthcare, Journal Year: 2024, Volume and Issue: 12(24), P. 2565 - 2565

Published: Dec. 20, 2024

Objectives: Occupational respiratory diseases represent a major public health concern worldwide. This study analyses the hospitalization costs and characteristics of four occupational diseases: malignant mesothelioma (MM), sinonasal cancer (SNC), pneumoconiosis (PN), hypersensitivity pneumonitis (HP). The findings are situated within context Italy’s population trends healthcare system, offering insights into economic clinical burden these diseases. Study Design: retrospective, population-based examines Italian hospitalizations for MM, SNC, PN, HP during period 2010–2021. primary outcomes were number hospitalizations, length stay, associated cost. Costs derived from charges linked to diagnosis-related groups (version 24) diagnostic category coding systems. Results: Though is rapidly aging, annual rate declined by 35% over period. SNC aligned with overall trend, PN MM experienced faster declines, whereas admissions remained steady. emerged as most resource-intensive (EUR 25 million yearly, 86% attributable occupation), followed 10 million, entirely occupational), 5 EUR 650,000 2 370,000 occupational). All studied had an average stay exceeding national one. shortest (6.5 days) least expensive 3647). In contrast, mean days, admission averaging 4700 4000 HP. median age was highest (78 years) (71 years), while patients approximately 65 years. Conclusions: Consistent their anticipated benefits, workplace regulations last three decades, including 1992 asbestos ban D.lgs. 81/2008, significant reductions in increased at discharge PN. fewer conclusions can be drawn due lower fractions (10–20%). finding suggests adding exposure flag hospital records acknowledged enhance surveillance. Finally, this provides first estimate fraction Italy.

Language: Английский

Citations

0