Trends in biotechnology,
Journal Year:
2024,
Volume and Issue:
42(8), P. 953 - 969
Published: Feb. 17, 2024
Urine-derived
stem
cells
(USCs)
are
a
promising
source
of
for
cell
therapy,
renal
toxicity
drug
testing,
and
disease
biomarker
discovery.
Patients'
own
USCs
can
be
used
precision
medicine.
In
this
review
we
first
describe
the
isolation
characterization
USCs.
We
then
discuss
preclinical
studies
investigating
use
in
exploring
utility
USC-derived
induced
pluripotent
(u-iPSCs)
as
biomarkers
diagnosis.
Finally,
challenges
using
these
applications
provide
insights
into
future
research
directions.
tool
advancing
Further
is
needed
to
explore
their
potential.
International Journal of Molecular Sciences,
Journal Year:
2024,
Volume and Issue:
25(17), P. 9592 - 9592
Published: Sept. 4, 2024
Spinal
cord
injury
(SCI)
is
a
catastrophic
condition
that
disrupts
neurons
within
the
spinal
cord,
leading
to
severe
motor
and
sensory
deficits.
While
current
treatments
can
alleviate
pain,
they
do
not
promote
neural
regeneration
or
functional
recovery.
Three-dimensional
(3D)
bioprinting
offers
promising
solutions
for
SCI
repair
by
enabling
creation
of
complex
tissue
constructs.
This
review
provides
comprehensive
overview
3D
techniques,
bioinks,
stem
cell
applications
in
repair.
Additionally,
it
highlights
recent
advancements
bioprinted
scaffolds,
including
integration
conductive
materials,
incorporation
bioactive
molecules
like
neurotrophic
factors,
drugs,
exosomes,
design
innovative
structures
such
as
multi-channel
axial
scaffolds.
These
strategies
offer
approach
optimizing
microenvironment,
advancing
understanding
state
repair,
offering
insights
into
future
directions
field
regenerative
medicine.
Frontiers in Aging,
Journal Year:
2025,
Volume and Issue:
6
Published: Jan. 24, 2025
Aging
research
has
rapidly
advanced
from
fundamental
discoveries
at
the
molecular
and
cellular
levels
to
promising
clinical
applications.
This
review
discusses
critical
translational
insights
that
bridge
gap
between
bench
bedside
applications,
highlighting
key
in
mechanisms
of
aging,
biomarkers,
therapeutic
interventions.
It
underscores
importance
interdisciplinary
approaches
collaboration
among
scientists,
clinicians,
policymakers
address
complexities
aging
improve
health
span.
