Efficacy of Artificial diets on biological characteristics of oriental fruit fly, Bactrocera dorsalis (Diptera: Tephritidae) in India DOI
Seema Ramniwas, Divya Singh, Aanchal Sharma

et al.

International Journal of Tropical Insect Science, Journal Year: 2023, Volume and Issue: 43(5), P. 1691 - 1700

Published: Sept. 13, 2023

Language: Английский

Host–diet–microbiota interplay in intestinal nutrition and health DOI Creative Commons

Anastasia Ignatiou,

Chrysoula Pitsouli

FEBS Letters, Journal Year: 2024, Volume and Issue: 598(20), P. 2482 - 2517

Published: June 30, 2024

The intestine is populated by a complex and dynamic assortment of microbes, collectively called gut microbiota, that interact with the host contribute to its metabolism physiology. Diet considered key regulator intestinal as ingested nutrients shape resident microbiota composition. Furthermore, recent studies underscore interplay dietary microbiota‐derived nutrients, which directly impinge on stem cells regulating their turnover ensure healthy barrier. Although advanced sequencing methodologies have allowed characterization human microbiome, mechanistic assessing diet–microbiota–host interactions depend use genetically tractable models, such Drosophila melanogaster . In this review, we first discuss similarities between fly intestines then focus effects diet nutrient‐sensing signaling cascades controlling cell self‐renewal differentiation, well disease. Finally, underline model in role gut‐related pathologies understanding mechanisms mediate different whole‐body manifestations dysfunction.

Language: Английский

Citations

5
Exploring Side Streams Upcycling for Crickets Farming: Insects Biology and Chemical Composition DOI

A. P. Fernandes,

Luisa Helena Cazarolli,

Thais Pigatto

et al.

Food Bioscience, Journal Year: 2025, Volume and Issue: unknown, P. 106431 - 106431

Published: March 1, 2025

Language: Английский

Citations

0
Influence of dietary variation on morphological development and post-mortem interval of Chrysomya rufifacies (Macquart, 1842) throughout its life stages DOI
Fahd A. Al‐Mekhlafi, Mohammed S. Al‐Khalifa, Muhammad A. Wadaan

et al.

Australian Journal of Forensic Sciences, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 12

Published: April 21, 2025

Language: Английский

Citations

0
Chemical Characterization and Beneficial Effects of Walnut Oil on a Drosophila melanogaster Model of Parkinson’s Disease DOI Creative Commons
Rossella Avallone, Cecilia Rustichelli, Monica Filaferro

et al.

Molecules, Journal Year: 2024, Volume and Issue: 29(17), P. 4190 - 4190

Published: Sept. 4, 2024

A nutritional approach could be a promising strategy to prevent or decrease the progression of neurodegenerative disorders such as Parkinson’s disease (PD). The neuroprotective role walnut oil (WO) was investigated in Drosophila melanogaster treated with rotenone (Rot), PD model, WO, their combination, and compared controls. WO reduced mortality improved locomotor activity impairment after 3 7 days, induced by Rot. LC-MS analyses fatty acid levels heads showed significant increase linolenic (ALA) linoleic (LA) both flies fed WO-enriched diet those association Flies supplemented an brain dopamine (DA) level, while Rot treatment significantly depleted content; conversely, did not modify DA content greater intake ALA LA enriched enhanced brain, suggesting polyunsaturated acids against Rot-induced neurotoxicity. involvement dopaminergic system improvement behavioral biochemical parameters is also suggested.

Language: Английский

Citations

2
Shared Transcriptomic Signatures of Inflammaging Among Diverse Strains ofDrosophila melanogaster DOI Open Access

Sabrina Isabel Perna,

Weihao Tang, Sydney Blimbaum

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 20, 2024

Abstract Background A prominent hallmark of aging is inflammaging—the increased expression innate immune genes without identifiable infection. Model organisms with shorter lifespans, such as the fruit fly, provide an essential platform for probing mechanisms inflammaging. Multiple groups have reported that, like mammalian models, old flies significantly higher levels anti-microbial peptide genes. However, whether some these genes—or any others—can serve reliable markers assessing and comparing inflammaging in different strains remains unclear. Methods Results We compared RNA-Seq datasets generated by groups. Although fly used studies differ significantly, we found that they share a core group strong aging-associated expression. In addition to genes, identified other prominently flies, especially SPH93 . further showed machine learning models can be predict “inflammatory age” fly. Conclusion may studying Drosophila profiles, combination machine-learning applied measure acceleration or deceleration

Language: Английский

Citations

0
Shared Transcriptomic Signatures of Inflammaging Among Diverse Strains of Drosophila melanogaster DOI Creative Commons

Sabrina Isabel Perna,

Weihao Tang, Sydney Blimbaum

et al.

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: April 3, 2024

Abstract Background: A prominent hallmark of aging is inflammaging—the increased expression innate immune genes without identifiable infection. Model organisms with shorter lifespans, such as the fruit fly, provide an essential platform for probing mechanisms inflammaging. Multiple groups have reported that, like mammalian models, old flies significantly higher levels anti-microbial peptide genes. However, whether some these genes—or any others—can serve reliable markers assessing and comparing inflammaging in different strains remains unclear. Methods Results: We compared RNA-Seq datasets generated by groups. Although fly used studies differ significantly, we found that they share a core group strong aging-associated expression. In addition to genes, identified other prominently flies, especially SPH93. further showed machine learning models can be predict “inflammatory age” fly. Conclusion: may studying Drosophila. profiles, combination machine-learning applied measure acceleration or deceleration

Language: Английский

Citations

0
Rearing conditions impacted efficacy of α-lipoic acid to influence longevity in Drosophila melanogaster fed with a high fat diet DOI Creative Commons
Debarati Chattopadhyay,

Susan Mary Philip,

Grace Prabhakar

et al.

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: June 12, 2024

Abstract Consumption of a high fat diet is accompanied with the risk obesity and early onset age-associated complications. Hence, dietary interventions are imperative to combat this. α-lipoic acid has been shown hinder diet-induced in model organisms. Recent studies hint at probable lifespan extending efficacy as well. Drosophila melanogaster emerged robust organism for longevity studies. In this study, was investigated its improve physiology Canton-S strain fed diet. Furthermore, mating status significant impact on survival fruit-flies, flies were reared two experimental groups – group one which males females together separately. one, improved mean lifespan, reduced fecundity body weight dose range 2mM 2.5mM, respectively. two, 1mM Improved climbing efficiency observed 1.5mM 2.5mM Administration resistance oxidative stress only female whereas both male exhibited Male showed heat shock 2.5mM. Only small improvement recovery time following cold No change starvation any either flies. To summarize, data from study suggested gender dependent diet; also significantly impacted by due varied rearing conditions.

Language: Английский

Citations

0
Influence of α-lipoic acid on longevity and stress resistance in Drosophila melanogaster fed with a high-fat diet DOI
Debarati Chattopadhyay,

Susan Mary Philip,

Grace Prabhakar

et al.

Biogerontology, Journal Year: 2024, Volume and Issue: 25(6), P. 1097 - 1114

Published: July 24, 2024

Language: Английский

Citations

0
Lithium affects sodium balance but not intestinal microbiota - studies in Drosophila melanogaster DOI Creative Commons
Katharina Jans,

Tobias Jöckel,

Jakob von Frieling

et al.

Journal of Trace Elements in Medicine and Biology, Journal Year: 2024, Volume and Issue: 86, P. 127548 - 127548

Published: Oct. 18, 2024

Language: Английский

Citations

0
Circulating triacylglycerides influence egg‐to‐adult viability in Drosophila melanogaster DOI
Ayesha Aslam, Urooj Javed, Mushtaq Hussain

et al.

Physiological Entomology, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 25, 2024

Abstract Triacylglycerides (TAGs) are neutral lipids and one of the major energy storage forms in an insect aiding normal physiology including reproduction organism. Importance TAG metabolism gametogenesis has been investigated insects like mosquitoes, silkworm Drosophila . However, a direct association between levels egg‐to‐adult viability not explored. In this study, we have assessed both stored circulating melanogaster lines with varying genetic backgrounds established through inbreeding recombinant strategies. We found noticeable variation D. lines. Apparently higher also had viability. To validate this, analysis these variations supervised correlation unsupervised K‐means clustering showed that positively associated irrespective gender. The findings suggest promotes successful transition egg to adult. Taken together, only potential application husbandry ecologically economically important but holds importance translational research fertility vertebrates humans.

Language: Английский

Citations

0