Drug Delivery Based on Nanoparticulate Systems DOI Creative Commons
Kemal Çetin, Koray Şarkaya

Düzce Üniversitesi Bilim ve Teknoloji Dergisi, Journal Year: 2024, Volume and Issue: 12(4), P. 1993 - 2015

Published: Oct. 22, 2024

The administration route of an active ingredient and the materials used to deliver it are as important synthesis that ingredient. For treatment be effective, must present in right amount place at time. Therefore, researchers have been studying a wide variety drug delivery systems, taking into account drug, its half-life, effective toxic amounts. Because numerous benefits, nanotechnology has attracted attention pharmaceutical research well many other fields. Nanoparticles potential disperse hydrophobic drugs aqueous solution, targeted site, thus selectively direct therapeutic agents such antineoplastic drugs. This study provides detailed discussion inorganic, polymeric, lipid-based nanoparticulate systems designed for delivery.

Language: Английский

Nutraceuticals for Diabetic Retinopathy: Recent Advances and Novel Delivery Systems DOI Open Access
Xiaoyuan Ye, Nicholas Fung, Wai‐Ching Lam

et al.

Nutrients, Journal Year: 2024, Volume and Issue: 16(11), P. 1715 - 1715

Published: May 30, 2024

Diabetic retinopathy (DR) is a major vision-threatening disease among the working-age population worldwide. Present therapeutic strategies such as intravitreal injection of anti-VEGF and laser photocoagulation mainly target proliferative DR. However, there need for early effective management in patients with stage DR before its progression into more severe sight-threatening stage. Nutraceuticals, natural functional foods few side effects, have been proposed to be beneficial Over decades, many studies, either vitro or vivo, demonstrated advantages number nutraceuticals their antioxidative, anti-inflammatory, neuroprotective, vasoprotective effects. only clinical trials conducted, outcomes varied. The low bioavailability instability indeed hindered utilization use. In this context, nanoparticle carriers developed deliver improve bioavailability. Despite preclinical nature, research interventive may yield promising information applications.

Language: Английский

Citations

5
Progressing nanotechnology to improve diagnosis and targeted therapy of Diabetic Retinopathy DOI Open Access
Roghayyeh Baghban, Roghayyeh Baghban, Alireza Attar

et al.

Biomedicine & Pharmacotherapy, Journal Year: 2025, Volume and Issue: 183, P. 117786 - 117786

Published: Jan. 2, 2025

Language: Английский

Citations

0
What do You Need to Know after Diabetes and before Diabetic Retinopathy? DOI Creative Commons
Shiyu Zhang, Jia‐Ren Liu, Heng Zhao

et al.

Aging and Disease, Journal Year: 2025, Volume and Issue: unknown, P. 0 - 0

Published: Jan. 1, 2025

Diabetic retinopathy (DR) is a leading cause of vision impairment and blindness among individuals with diabetes mellitus. Current clinical diagnostic criteria mainly base on visible vascular structure changes, which are insufficient to identify diabetic patients without DR (NDR) but dysfunctional retinopathy. This review focuses retinal endothelial cells (RECs), the first sense respond elevated blood glucose. As glucose rises, RECs undergo compensatory transitional phases, correspondingly altered molecules likely become biomarkers targets for early prediction treatment NDR article elaborated possible pathophysiological processes focusing summarized recently published reliable screening emerging intervention strategies Additionally, references medication selection lifestyle recommendations this population provided. aims deepen understanding REC biology pathophysiology, emphasizes importance detection intervention, points out future directions improve diagnosis reduce occurrence DR.

Language: Английский

Citations

0
In vivo antihyperglycemic effect of Ptilostemon casabonae (L.) Greuter leaf extract and its liposomal formulation DOI Creative Commons

Simone Pani,

Carla Caddeo, Laura Dazzi

et al.

Journal of Drug Delivery Science and Technology, Journal Year: 2024, Volume and Issue: 100, P. 106078 - 106078

Published: Aug. 23, 2024

ou non, émanant des établissements d'enseignement et de recherche français étrangers, laboratoires publics privés.

Citations

1
The role of metal nanocarriers, liposomes and chitosan-based nanoparticles in diabetic retinopathy treatment: A review study DOI
Junling Liu, Feng Zhang, Xiaolong Shi

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: unknown, P. 139017 - 139017

Published: Dec. 1, 2024

Language: Английский

Citations

1
Drug Delivery Based on Nanoparticulate Systems DOI Creative Commons
Kemal Çetin, Koray Şarkaya

Düzce Üniversitesi Bilim ve Teknoloji Dergisi, Journal Year: 2024, Volume and Issue: 12(4), P. 1993 - 2015

Published: Oct. 22, 2024

The administration route of an active ingredient and the materials used to deliver it are as important synthesis that ingredient. For treatment be effective, must present in right amount place at time. Therefore, researchers have been studying a wide variety drug delivery systems, taking into account drug, its half-life, effective toxic amounts. Because numerous benefits, nanotechnology has attracted attention pharmaceutical research well many other fields. Nanoparticles potential disperse hydrophobic drugs aqueous solution, targeted site, thus selectively direct therapeutic agents such antineoplastic drugs. This study provides detailed discussion inorganic, polymeric, lipid-based nanoparticulate systems designed for delivery.

Language: Английский

Citations

0