Diammonium glycyrrhizinate alleviates iron overload-induced liver injury in mice via regulating the gut-liver axis DOI
Yu Liu, Xiaohong Li, Ziwei Guo

et al.

Phytomedicine, Journal Year: 2024, Volume and Issue: 135, P. 156216 - 156216

Published: Nov. 8, 2024

Language: Английский

Editorial for Special Issue: “Molecular Mechanisms Underlying Fatty Liver Disease: From Pathogenesis to Treatment” DOI Creative Commons
Haibo Dong

Current Issues in Molecular Biology, Journal Year: 2025, Volume and Issue: 47(3), P. 160 - 160

Published: Feb. 27, 2025

Metabolic-dysfunction-associated fatty liver disease (MAFLD) and alcohol-associated (ALD) represent two of the most prevalent chronic diseases globally, collectively affecting hundreds millions individuals [...]

Language: Английский

Citations

0
Review of the mechanisms of the biliary-enteric axis in the development of cholangiocarcinoma DOI

Tianhao Shen,

Xue Yu, Cheng Zhou

et al.

World Journal of Clinical Oncology, Journal Year: 2025, Volume and Issue: 16(4)

Published: March 26, 2025

Cholangiocarcinoma (CCA) is a particularly aggressive and challenging type of cancer, known for its poor prognosis, which worsened by the complex interplay various biological environmental factors that contribute to development. Recently, researchers have increasingly focused on significant role biliary-enteric communication liver-gut axis in pathogenesis CCA, highlighting relationship has not been thoroughly explored before. This review aims summarize key concepts related investigate potential mechanisms may lead onset progression disease presents substantial treatment challenges. Important areas focus will include microbiome's profound influence, interacts with host physiology ways worsen cancer development; changes bile acid metabolism can create toxic environments favorable tumor growth; regulation inflammatory processes either promote or inhibit progression; immune system's involvement, crucial body's response cancer; interactions within metabolic pathways affect cellular behavior dynamics. By integrating recent research findings from studies, we aim explore multifaceted roles providing new insights perspectives future while identifying promising therapeutic targets could innovative strategies aimed at improving patient outcomes this disease.

Language: Английский

Citations

0
Probiotics may be useful for drug-induced liver dysfunction in patients with depression – A secondary analysis of a randomized clinical trial DOI Creative Commons
Oliwia Gawlik-Kotelnicka,

Jacek Burzyński,

Jakub Rogalski

et al.

Clinical Nutrition ESPEN, Journal Year: 2024, Volume and Issue: 63, P. 604 - 614

Published: July 30, 2024

There is a need to identify new treatment options for depression with its comorbidities. Depression often coexists liver steatosis and the two may share pathophysiological overlap, including inflammation microbiota changes. Probiotics might represent safe option as an adjunctive therapy in patients possible steatosis. The paper presents secondary analysis of clinical trial effect probiotic supplementation on levels non-invasive markers fibrosis adult depressive disorders.

Language: Английский

Citations

2
Alleviation of Alcoholic Liver Injury through Composite Postbiotics Regulation of Intestinal Flora and Promotion of Bile Acid Metabolism DOI
Qi Peng,

Kaiming Yang,

Qifan Hou

et al.

Food Bioscience, Journal Year: 2024, Volume and Issue: unknown, P. 105379 - 105379

Published: Oct. 1, 2024

Language: Английский

Citations

2
Diammonium glycyrrhizinate alleviates iron overload-induced liver injury in mice via regulating the gut-liver axis DOI
Yu Liu, Xiaohong Li, Ziwei Guo

et al.

Phytomedicine, Journal Year: 2024, Volume and Issue: 135, P. 156216 - 156216

Published: Nov. 8, 2024

Language: Английский

Citations

2