Marine Drugs,
Journal Year:
2024,
Volume and Issue:
22(12), P. 562 - 562
Published: Dec. 17, 2024
Collagen,
a
critical
biomaterial
with
wide
applications
in
pharmaceuticals,
cosmetics,
and
medical
industries,
can
be
sourced
sustainably
from
fish
scales.
This
study
optimizes
the
extraction
of
collagen
using
Tris-Glycine
buffer
scales
via
Taguchi
method.
Various
parameters—buffer
concentration,
temperature,
pH,
time—were
evaluated
to
identify
optimal
conditions.
Under
conditions
(0.5
M
acetic
acids,
volume
acids
100
mL,
soaking
time
120
min,
10
mL),
results
demonstrate
that
temperature
concentration
significantly
influence
yield,
purity
17.14
±
0.05
mg/g.
R2
value
73.84%
was
obtained
for
mathematical
model).
FTIR
analysis
confirmed
presence
characteristic
peaks
at
1611
cm−1
(amide
I),
1523
II),
1300
III),
indicating
successful
type
I
collagen.
SDS-PAGE
revealed
protein
banding
pattern
consistent
molecular
weight
collagen,
amino
acid
shows
high
percentages
glycine
(20.98%),
proline
(15.43%),
hydroxyproline
(11.51%),
implying
fibrous
structures.
The
finding
suggests
method
offers
an
efficient
sustainable
approach
extraction,
reducing
waste
processing
industries.
Nevertheless,
there
is
need
further
experimental
validation
align
modeling
on
optimized
Biomolecules,
Journal Year:
2025,
Volume and Issue:
15(1), P. 88 - 88
Published: Jan. 9, 2025
One
class
of
cosmetic
compounds
that
have
raised
interest
many
experts
is
peptides.
The
search
for
ingredients
with
good
biocompatibility
and
bioactivity
has
led
to
the
use
peptides
in
products.
Peptides
are
novel
active
improve
collagen
synthesis,
enhance
skin
cell
proliferation,
or
decrease
inflammation.
Based
on
their
mechanism
action,
they
can
be
classified
into
signal
peptides,
carrier
neurotransmitter
inhibitor
enzyme
This
review
focuses
main
types
application
field,
underlining
limitations.
most
significant
drawbacks
poor
permeability
through
membranes,
which
limits
delivery
effectiveness.
As
a
result,
this
follows
methods
used
improving
stratum
corneum.
Increasing
peptide
bioavailability
stability
enhanced
desired
site
action
visible
effects
become
central
points
latest
research
due
promising
features.
For
purpose,
several
been
identified
described.
Physical
techniques
include
thermal
ablation
(radiofrequency
laser),
electrical
(electroporation,
iontophoresis),
mechanical
approach
(microneedles),
ultrasounds.
an
alternative,
innovative
formulations
developed
nano-systems
such
as
liposomes,
niosomes,
ethosomes,
nanoemulsions,
other
nanomaterials
reduce
irritation
product
purpose
provide
information
regarding
these
noteworthy
molecules
reasoning
behind
formulations.
International Journal of Biological Macromolecules,
Journal Year:
2024,
Volume and Issue:
278, P. 134374 - 134374
Published: Aug. 3, 2024
The
consumption
of
animal
products
has
witnessed
a
significant
increase
over
the
years,
leading
to
growing
need
for
industries
adopt
strict
waste
control
measures
mitigate
environmental
impacts.
disposal
in
landfill
can
result
diverse
and
potentially
hazardous
decomposition
by-products.
Animal
by-products,
derived
from
meat,
poultry,
seafood
fish
industries,
offer
substantial
raw
material
source
collagen
gelatin
production
due
their
high
protein
content.
Collagen,
being
major
component
tissues,
represents
an
abundant
resource
that
finds
application
various
chemical
industries.
demand
collagen-based
continues
grow,
yet
availability
primary
remains
limited
insufficient
meet
projected
needs.
Consequently,
repurposing
materials
contain
provides
opportunity
this
while
at
same
time
minimizing
amount
is
dumped.
This
review
examines
potential
extract
value
content
present
animal-derived
It
systematic
evaluation
different
species
groups
discusses
approaches
processing
fabricating
repurposed
collagen.
specifically
focuses
on
research,
encompassing
examination
its
physical
properties,
as
well
modifications.
We
have
detailed
how
research
knowledge
built
structure
function
will
drive
new
initiatives
lead
development
opportunities
future.
Additionally,
it
highlights
emerging
extracting
high-quality
efforts
fabricate
original
within
chemical,
biomedical
science-based
Fermentation,
Journal Year:
2024,
Volume and Issue:
10(6), P. 315 - 315
Published: June 14, 2024
The
global
food
production
system
faces
several
challenges,
including
significant
environmental
impacts
due
to
traditional
agricultural
practices.
rising
demands
of
consumers
for
products
that
are
safe,
healthy,
and
have
animal
welfare
standards
led
an
increased
interest
in
alternative
proteins
the
development
cellular
agriculture
field.
Within
this
innovative
field,
precision
fermentation
has
emerged
as
a
promising
technological
solution
produce
with
reduced
ecological
footprints.
This
review
provides
summary
related
current
production,
explores
how
can
contribute
address
these
issues.
Additionally,
we
report
on
main
animal-derived
produced
by
fermentation,
particular
focus
those
used
nutraceutical
industries.
general
principles
will
be
explained,
strain
bioprocess
optimization.
Examples
efficient
recombinant
protein
bacteria
yeasts,
such
milk
proteins,
egg-white
structural
flavoring
also
addressed,
along
case
examples
companies
producing
at
commercial
scale.
Through
examples,
explore
supports
sustainable
holds
potential
innovations
sector.
Polymers,
Journal Year:
2024,
Volume and Issue:
16(18), P. 2668 - 2668
Published: Sept. 22, 2024
Biomaterials
have
been
the
subject
of
extensive
research,
and
their
applications
in
medicine
pharmacy
are
expanding
rapidly.
Collagen
its
derivatives
stand
out
as
valuable
biomaterials
due
to
high
biocompatibility,
biodegradability,
lack
toxicity
immunogenicity.
This
review
comprehensively
examines
collagen
from
various
sources,
extraction
processing
methods,
structural
functional
properties.
Preserving
native
state
is
crucial
for
maintaining
beneficial
characteristics.
The
challenges
associated
with
chemically
modifying
tailor
properties
specific
clinical
needs
also
addressed.
discusses
collagen-based
biomaterials,
including
solutions,
hydrogels,
powders,
sponges,
scaffolds,
thin
films.
These
materials
broad
regenerative
medicine,
tissue
engineering,
drug
delivery,
wound
healing.
Additionally,
highlights
current
research
trends
related
derivatives.
may
significantly
influence
future
developments,
such
using
bioinks
3D
bioprinting
or
exploring
new
nanoparticle
preparation
methods
delivery
systems.
Journal of Research in Pharmacy,
Journal Year:
2025,
Volume and Issue:
29(1), P. 1 - 10
Published: March 3, 2025
The
rose
plant
has
been
used
by
different
societies
throughout
human
history
for
beauty
and
health
purposes.
Rosa
damascena
Mill.,
R.
gallica
L.,
phoenicia
Boiss
belong
to
the
Rosaceae
family
are
hybrid
plants
of
species.
study
aims
develop
an
acne
mask
containing
natural
ingredients
using
pulp
produced
in
Isparta
region
released
into
environment
as
waste.
sample
was
prepared
Milestone
ETHOS
ONE
microwave
unit.
included
addition
nitric
acid
hydrogen
peroxide
solution
use
wet
digestion
method
analyzed
pour
plate
method.
formulation
consists
pulp,
thermal
water,
clay,
glycerin,
aloe
vera,
hyaluronic
acid,
preservative,
EDTA,
sodium
gluconate.
research
led
a
that
maintains
absorption,
moisturizing,
renewal
properties.
two
formulations
exhibited
fastest
drying
times
were
GP-AMF-10
GP-AMF-8,
with
10.21
10.40,
respectively.
Microbiological
analysis
resulting
product
conducted
it
determined
comply
microbiological
limit
values.
After
comprehensive
evaluation,
found
selected
demonstrated
superior
characteristics..
Journal of Enzyme Inhibition and Medicinal Chemistry,
Journal Year:
2025,
Volume and Issue:
40(1)
Published: April 11, 2025
Skin
ageing
is
a
complex
physiological
process
primarily
characterised
by
the
deepening
of
wrinkles
and
sagging
skin.
Collagen
essential
for
maintaining
skin
elasticity
firmness.
As
ages,
it
experiences
structural
functional
changes
in
collagen,
including
decrease
collagen
synthesis
an
increase
hydrolysis.
Thus,
promoting
represents
practical
strategy
mitigating
ageing.
This
review
systematically
described
functions,
classifications
biosynthesis
as
well
its
role
Additionally,
major
signalling
pathways
targets
associated
with
were
also
discussed.
More
importantly,
provided
detailed
summary
natural
products
synthesis-promoting
effects
highlighted
small
molecule
compounds
potential
anti-ageing
activity,
especially
PPARδ
agonists.
The
relevant
content
offers
lead
development
anti-skin
therapies.
Biomaterials
have
been
the
subject
of
extensive
research,
with
their
applications
in
medicine
and
pharmacy
expanding
rapidly.
Collagen
its
derivatives
stand
out
as
valuable
biomaterials
due
to
high
biocompatibility,
biodegradability,
lack
toxicity
immunogenicity.
This
review
comprehensively
examines
collagen
from
various
sources,
extraction
processing
methods,
structural
functional
properties.
Preserving
native
state
is
crucial
for
maintaining
beneficial
characteristics.
The
challenges
associated
chemically
modifying
tailor
properties
specific
clinical
needs
are
also
addressed.
discusses
collagen-based
biomaterials,
including
solutions,
hydrogels,
powders,
sponges,
scaffolds,
thin
films.
These
materials
broad
regenerative
medicine,
tissue
engineering,
drug
delivery,
wound
healing.
Additionally,
highlights
current
research
trends
related
derivatives.
may
significantly
influence
future
developments,
such
using
bioinks
3D
bioprinting
or
exploring
new
nanoparticle
preparation
methods
delivery
systems.
