Innovative Alkanediol-Based Eutectic Solvents for Extracting/Pre-Formulating Dermatologically Valuable Free Fatty Acids from Spirulina and Porphyridium Cakes DOI Creative Commons
Laura Wils, Mervé Yagmur,

Nicolas Bellin

et al.

Marine Drugs, Journal Year: 2024, Volume and Issue: 22(6), P. 281 - 281

Published: June 15, 2024

The growing demand for phycobiliproteins from microalgae generates a significant volume of by-products, such as extraction cakes. These cakes are enriched with products interest the cosmetics market, namely free fatty acids, particularly polyunsaturated (PUFA). In this work, two cakes, one spirulina and Porphyridium cruentum, were valorized using innovative natural hydrophobic deep eutectic solvents (NaDES) based on alkanediols. most promising NaDES, determined by physicochemical properties screening, mixtures alkanediols acids. include 1,3-propanediol octanoic acid (1:5, mol/mol) decanoic (1:3:1, mol/mol). Two extractive processes implemented: ultrasound-assisted an mechanical process involving dual asymmetric centrifugation. second resulted in production extracts significantly PUFA, ranging 65 to 220 mg/g dry matter NaDES demonstrated good safety respect epidermal keratinocyte viability (>80% at 200 µg/mL). study their impact commensal pathogenic cutaneous bacteria effects Staphylococcus aureus epidermidis (>50% decrease µg/mL) while preserving Corynebacterium xerosis Cutibacterium acnes. results highlight potential valorizing these co-products alkanediol-based strategy combining active vector growth regulator extract, management dysbiosis staphylococci.

Language: Английский

Single-step extraction/pre-formulation process for B-phycoerythrin using glycerol-based eutectic solvents: A step toward more sustainable production of phycobiliproteins DOI Creative Commons

Louise Van Gheluwe,

Solène Odou,

Mervé Yagmur

et al.

Sustainable Chemistry and Pharmacy, Journal Year: 2024, Volume and Issue: 40, P. 101654 - 101654

Published: June 13, 2024

Language: Английский

Citations

4
Development of a Ready-to-Use Oxyresveratrol-Enriched Extract from Artocarpus lakoocha Roxb. Using Greener Solvents and Deep Eutectic Solvents for a Whitening Agent DOI Creative Commons

Krittanon Saesue,

Pornnapa Thanomrak,

Wipawan Prompan

et al.

Cosmetics, Journal Year: 2024, Volume and Issue: 11(2), P. 58 - 58

Published: April 5, 2024

Oxyresveratrol (ORV) is naturally found in Artocapus lakoocha Roxb. (AL), similar to resveratrol. This AL extract has demonstrated considerable importance dietary supplements and cosmetics for its anti-tyrosinase antioxidant properties. There a great demand ORV the cosmetic pharmaceutical industries. Traditionally, harsh solvents have been used from AL. study aims address this issue by introducing green technology with ready-to-use enrichment of extraction using deep eutectic (DESs). Thirty-three DESs were synthesized characterized. The efficiency these was evaluated content (g ORV/kg dried plant) compared conventional solvents, analyzed validated HPLC. Notably, two DESs, namely choline chloride/citric acid/water (2:1:3) (DES10) chloride/xylose (1:1) (DES17), showed higher than therefore selected optimization conditions Box–Behnken designs, considering three variable levels: time, temperature, water as co-solvents. Interestingly, biological activities ORV-enriched extracts DES10 DES17 evaluated, results that they 74-fold 252-fold more potent kojic acid terms tyrosinase inhibitory activity. 17-fold antioxidants ascorbic acid. morphology powder before after under SEM suggested same mechanism classical organic solvents. These can be directly incorporated into formulations production scales without need prepare stock solution are referred extracts. successfully pioneered use environmentally friendly highly efficient produce applications

Language: Английский

Citations

3
Valorisation of Raspberry Seeds in Cosmetic Industry-Green Solutions DOI Creative Commons
Ivanka Ćirić, Dragana Dabić Zagorac, Milica Sredojević

et al.

Pharmaceutics, Journal Year: 2024, Volume and Issue: 16(5), P. 606 - 606

Published: April 29, 2024

The fruit processing industry generates large quantities of by-products well known to be rich in bioactive compounds with numerous nutritional properties and beneficial effects for human health. We developed a strategy valorise raspberry seeds obtain valuable ingredients potential application cosmetic skincare formulas. Cold press extraction technology was applied extract oil, the remaining defatted seed cake treated three proline based deep eutectic solvents (DES) polyphenols. most potent proline/citric acid extract, free total ellagic content (52.4 mg/L 86.4 mg/L), phenolic (TPC, 550.1 mg GAE/L) radical scavenging activity (RSA, 4742.7 mmol TE/L). After direct mixing after encapsulation starch as carrier, emulsion microemulsion were characterised by irritation (Zein test), transepidermal water loss (TEWL), red blood cell (RBC), DPPH antioxidant test. resulting preparations improved quality comparison control hand cream, low skin effect, lower TEWL, higher potential. This work complies circular economy principles green standards, represents efficient model on how reuse natural resources through waste minimization.

Language: Английский

Citations

3
Innovative Alkanediol-Based Eutectic Solvents for Extracting/Pre-Formulating Dermatologically Valuable Free Fatty Acids from Spirulina and <em>Porphyridium </em>Cakes DOI Open Access
Laura Wils, Mervé Yagmur,

Nicolas Bellin

et al.

Published: May 27, 2024

The growing demand for phycobiliproteins from microalgae generates a significant volume of by-products, such as extraction cakes. These cakes are enriched with products interest the cosmetic market, namely free fatty acids, particularly polyunsaturated (PUFA). In this work, two cakes, one spirulina and Porphyridium cruentum, were valorized using innovative natural hydrophobic deep eutectic solvents (NaDES) based on alkanediols. most promising NaDES, determined by physicochemical properties screening, mixtures alkanediol acid. include mixture 1,3-propanediol octanoic acid (1:5, mol/mol) decanoic (1:3:1, mol/mol). Two extractive processes implemented: ul-trasound-assisted an mechanical process dual asymmetric centrifu-gation. second resulted in production extracts significantly PUFA, ranging 65 to 220 mg/g dry matter NaDES demonstrated good safety respect epidermal keratinocyte viability. study their impact com-mensal pathogenic cutaneous bacteria effects viability Staphy-lococcus aureus Staphylococcus epidermidis while preserving Corynebacterium xerosis Cuti-bacterium acnes. results highlight potential valorizing these co-products al-kanediol-based strategy combining active vector growth regulator extract, management dysbiosis involving staphylococci.

Language: Английский

Citations

1
Innovative Alkanediol-Based Eutectic Solvents for Extracting/Pre-Formulating Dermatologically Valuable Free Fatty Acids from Spirulina and Porphyridium Cakes DOI Creative Commons
Laura Wils, Mervé Yagmur,

Nicolas Bellin

et al.

Marine Drugs, Journal Year: 2024, Volume and Issue: 22(6), P. 281 - 281

Published: June 15, 2024

The growing demand for phycobiliproteins from microalgae generates a significant volume of by-products, such as extraction cakes. These cakes are enriched with products interest the cosmetics market, namely free fatty acids, particularly polyunsaturated (PUFA). In this work, two cakes, one spirulina and Porphyridium cruentum, were valorized using innovative natural hydrophobic deep eutectic solvents (NaDES) based on alkanediols. most promising NaDES, determined by physicochemical properties screening, mixtures alkanediols acids. include 1,3-propanediol octanoic acid (1:5, mol/mol) decanoic (1:3:1, mol/mol). Two extractive processes implemented: ultrasound-assisted an mechanical process involving dual asymmetric centrifugation. second resulted in production extracts significantly PUFA, ranging 65 to 220 mg/g dry matter NaDES demonstrated good safety respect epidermal keratinocyte viability (>80% at 200 µg/mL). study their impact commensal pathogenic cutaneous bacteria effects Staphylococcus aureus epidermidis (>50% decrease µg/mL) while preserving Corynebacterium xerosis Cutibacterium acnes. results highlight potential valorizing these co-products alkanediol-based strategy combining active vector growth regulator extract, management dysbiosis staphylococci.

Language: Английский

Citations

1