Polish Journal of Environmental Studies,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Aug. 5, 2024
The
resistance
of
fungal
pathogens
to
traditional
antifungal
medications
presents
a
significant
public
health
concern,
particularly
for
immunocompromised
patients,
leading
elevated
rates
illness
and
death.This
study
aimed
explore
the
properties
zinc
oxide
nanoparticles
(ZnO
NPs)
produced
using
natural
approach
involving
aqueous
seed
extract
Trigonella
foenumgracium
(Fenugreek).Additionally,
assessed
combined
effectiveness
these
biologically
synthesized
ZnO
NPs
with
fluconazole
against
pathogens.The
were
observed
have
hexagonal
shape
an
average
diameter
27
nm
surface
charge
-18.3
mV.Notably,
exhibited
most
potent
activity
Candida
tropicalis,
relative
inhibition
zone
18.67±0.56mm.The
minimum
inhibitory
concentration
C.
tropicalis
was
determined
be
100
µg/mL,
while
fungicidal
found
200
µg/mL.The
greatest
synergistic
effect
between
glabrata,
followed
by
parapsilosis.In
summary,
underscores
potential
combining
formulate
effective
treatment
drug-resistant
pathogens,
thereby
enhancing
therapeutic
efficacy
conventional
drugs.
Journal of the Chinese Chemical Society,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Dec. 17, 2024
Abstract
Metal
oxide
nanoparticles
(MONPs),
pivotal
in
cutting‐edge
research,
are
examined
comprehensively
this
article.
Encompassing
definition,
types,
and
applications,
the
focus
intensifies
on
synthesis
methods.
Detailed
discussions
include
chemical
approaches
for
silver
oxide,
zinc
nickel
copper
tin
NPs.
Additionally,
article
emphasizes
burgeoning
significance
of
green
methods
tailoring
these
The
applications
section
underscores
their
role
wastewater
treatment,
water
splitting,
biomedical
fields.
This
targeted
resource
offers
in‐depth
insights
into
MONP
synthesis,
bridging
gap
between
traditional
environmentally
conscious
methodologies,
researchers
practitioners
emerging
technologies.
In
article,
future
perspectives
also
discussed.
Veterinary World,
Journal Year:
2025,
Volume and Issue:
unknown, P. 263 - 269
Published: Feb. 1, 2025
Background
and
Aim:
The
development
of
zinc-based
antimicrobials
has
progressed
from
conventional
to
nanoparticle
(NP)
formulations
due
their
enhanced
biological
properties.
This
study
evaluates
the
antibacterial
efficacy
green-synthesized
zinc
oxide
NPs
(ZnO-NPs)
derived
Garcinia
mangostana
leaf
extract
against
both
pathogenic
non-pathogenic
bacteria
relevant
poultry
health.
Materials
Methods:
Using
a
completely
randomized
design,
six
treatment
groups
were
tested:
Positive
control
(PC)
(tetracycline,
2.5
mg/mL),
negative
(NC)
(HCl
0.1
N
+
distilled
water),
ZnO-NPs
at
concentrations
2.5,
5,
7.5,
10
mg/mL.
antimicrobial
activity
was
assessed
using
agar
well
diffusion
method,
measuring
inhibition
zones
Escherichia
coli,
S.
Typhimurium,
Staphylococcus
aureus,
Lactobacillus
plantarum.
Results:
positive
demonstrated
most
significant
across
all
bacterial
strains.
exhibited
dose-dependent
activity,
with
maximum
recorded
as
18.58
mm
for
E.
17.09
17.41
aureus
highest
concentration
(10
mg/mL).
However,
L.
plantarum
less
pronounced,
zone
9.93
mm.
These
findings
indicate
selective
toxicity
ZnO-NPs,
favoring
over
Conclusion:
Green-synthesized
G.
demonstrate
promising
properties
pathogens.
Their
action
highlights
potential
applications
eco-friendly
feed
additives
improve
health
mitigate
risks.
Keywords:
antibacterial,
green
synthesis,
nanotechnology,
health,
nanoparticles.
Scientific Reports,
Journal Year:
2024,
Volume and Issue:
14(1)
Published: Jan. 10, 2024
Abstract
In
this
study,
a
ZnO/MnO
nanocomposite
was
myco-fabricated
using
the
isolated
endophytic
Clonostachys
rosea
strain
EG99
as
nano-factory.
The
extract
of
EG99,
reducing/capping
agent,
successfully
titrated
with
equal
quantities
Zn(NO
3
)
2
·6H
O
and
Mn(NO
(precursors)
in
single
step
to
fabricate
rod-shaped
size
6.22
nm.
20
min,
results
were
validated
at
350
400
nm
UV–Vis
spectroscopy.
7-L
bioreactor,
an
industrial
biotechnological
approach
used
scale
up
biomass
strain,
yield
nanocomposite.
A
controlled
fed-batch
fermentation
system
specific
nitrogen/carbon
ratio
identical
feeding
schedule
production
process.
Higher
yields
obtained
by
adopting
bioreactor
regular
1:200.
Overall,
produced
89.2
g/l
its
maximum,
2.44
times
more
than
batch's
36.51
output.
Furthermore,
fed-batch's
maximum
79.81
g/l,
noteworthy
14.5-fold
increase
over
5.52
g/l.
Finally,
we
designed
innovative
manage
growth
mode,
supporting
rapid,
cheap
eco-friendly
myco-fabrication
At
dose
210
µg/ml,
tested
exhibited
antibacterial
activity
against
Staphylococcus
aureus
(98.31
±
0.8%),
Escherichia
coli
(96.70
3.29%),
Candida
albicans
(95.72
0.95%).
same
dose,
biofilm
eradicated
48
h;
however,
biofilms
needed
72
96
h,
respectively.
Our
showed
strong
highly
selective
antagonistic
effects
variety
multidrug-resistant
human
pathogens.
Therefore,
upcoming
generations
antibiotics,
it
might
be
employed
nano-antibiotic.
Research Square (Research Square),
Journal Year:
2024,
Volume and Issue:
unknown
Published: Feb. 13, 2024
Abstract
Novel
sulfur
zinc
nanoparticles
functionalized
with
thioglycolic
acid
were
synthetized
via
hydrothermal
route
and
tested
in
a
solar
radiation-based
dye
photodegradation
process.
These
characterized,
the
findings
revealed
that
was
strong
capping
ligand
for
generation
of
specific
surface
area
36.82
m
2
/g
7.15
nm
average
nanocrystal
size.
The
cubic
wurtzite
phases
these
confirmed
X-ray
diffraction.
quantum
confinement
effect
caused
larger
energy
band
gap
blue
shift
absorbance
contrast
to
bulk
zinc.
improved
adsorption
effectiveness
proved
remove
methylene
from
aqueous
solutions.
They
can
30.92
mg/g
molecule.
To
understand
synergy
between
photocatalysis,
used
analyze
prior
experimental
measurement
isotherms
kinetics.
rationalization
on
performed
calculated
statistical
physics
parameters
including
estimation
–
energy.
Dye
molecules
exhibited
physical
interactions
energies
25.92–23.31
kJ/mol.
sunlight-based
photocatalytic
activity
demonstrated
91.1%
degradation
efficiency
180
min.
Overall,
remained
almost
unchanged
after
five
consecutive
cycles
88
±
3%.
results
indicate
sustainable
be
applied
cleaning
industrial
urban
fluids
polluted
by
hazardous
organic
compounds
like
molecules.
Journal of Biomedical Materials Research Part B Applied Biomaterials,
Journal Year:
2025,
Volume and Issue:
113(2)
Published: Jan. 24, 2025
ABSTRACT
Schistosomiasis,
caused
by
Schistosoma
worms,
is
a
major
neglected
tropical
disease
in
Africa,
this
ranked
as
second
after
malaria.
Nanotechnology
important
for
treating
schistosomiasis
while
minimizing
chemotherapy
side
effects.
The
current
investigate
aimed
to
assess
the
effectiveness
of
biosynthesized
zinc
oxide
nanoparticles
(ZnO
NPs),
which
were
used
first
time
an
attempt
find
alternative
treatment
and
synthesized
Origanum
majorana
,
compare
them
with
praziquantel
(PZQ),
only
chemical
approved
World
Health
Organization.
study
included
evaluations
both
laboratory
vivo.
In
experiment,
adult
worms
exposed
ZnO
at
concentrations
100,
50,
25,
12.5,
6.25,
3.125
μg/mL
showed
highest
complete
mortality
rates
100
50
6
12
h,
respectively.
Combinations
12.5
+
0.4,
25
0.3,
0.2,
75
0.1
PZQ
also
tested.
vivo,
four
groups
hamsters
infected
haematobium
treated.
hamsters,
number
eggs
present
tissues
well
size
granulomas
significantly
decreased
when
combined
administered.
properties
particles
consistent
confirmed
all
previous
studies.
These
results
indicate
that
green
high
activity
against
S
.
experiments.
Arabian Journal for Science and Engineering,
Journal Year:
2024,
Volume and Issue:
49(7), P. 9067 - 9088
Published: Jan. 29, 2024
Abstract
In
our
study,
we
examined
how
well
six
Streptomyces
strains
bio-fabricated
ZnONPs,
MnONPs,
and/or
ZnO/MnO
2
nanocomposite.
The
most
potent
strain
that
generated
efficient
antimicrobial
nanoparticles
was
then
picked
to
increase
the
production
of
those
particles
in
a
semi-industrial
pilot
plant
unit.
Consequently,
intracellular
extract
endophytic
coelicolor
E72
used
achieve
bio-fabrication
reaction
spherical
nanocomposite
(6–18
nm).
validated
and
characterized
using
FTIR,
XRD,
SEM,
TEM,
TGA,
EDS
analyses.
Additionally,
this
nanocomponent
scaled
up
unit
with
size.
Plackett–Burman
experimental
method
maximize
nanocomposites,
which
had
increased
2.7-fold
from
their
initial
state.
subsequently
31.25
times
an
exponential
pulse-feeding
fermentation
technique
70-L
bioreactor.
This
exhibited
effective
efficacy
against
all
tested
antibiotic-resistant
human
pathogens.
effects
Salmonella
paratyphi
(53.17
±
2.8
mm)
Candida
albicans
(50.2
1.01
were
at
90
130
µg/ml
nanocomposite,
respectively.
is
first
full
explanation
scale
employing
as
reducing/capping
agent
reacted
MnCl
·4H
O
Zn
(CH
3
COO)
·2H
precursors.
has
potential
be
utilized
development
pharmaceuticals,
cosmetics,
wound
dressings,
burn
therapy
due
its
powerful
capabilities.