Cognitive Function and Brain Structure in COVID-19 Survivors: The Role of Persistent Symptoms DOI Creative Commons
Krupa Vakani, Ray Norbury, Martina Vanova

et al.

Behavioural Brain Research, Journal Year: 2024, Volume and Issue: 476, P. 115283 - 115283

Published: Oct. 3, 2024

Persistent COVID-19 symptoms post-acute state have been shown to a significant negative impact on brain structure and function. In this study, we conducted magnetic resonance imaging (MRI) of the whole in 43 working-age adults (mean age: 44.79±10.80; range: 24-65 years) with history (731.17±312.41 days post-diagnosis), also assessed their cognitive function (processing speed, attention, working memory, executive function, recognition memory), mental health, sleep quality. MRI data were processed using FSL derive regional volumes for bilateral nucleus accumbens, caudate, pallidum, putamen, thalamus, amygdala, hippocampus, total grey matter, white cerebral spinal fluid volume, analysed relation persistent symptom load, Higher load was significantly associated smaller putamen lower response accuracy memory tasks, as well longer time complete task, poorer health Smaller fully mediated relationship between Further research is required confirm whether reduced volume its association poor persists survivors long term.

Language: Английский

Comprehensive MRI assessment reveals subtle brain findings in non-hospitalized post-COVID patients with cognitive impairment DOI Creative Commons

Serena Fineschi,

Markus Fahlström, David Fällmar

et al.

Frontiers in Neuroscience, Journal Year: 2024, Volume and Issue: 18

Published: Sept. 10, 2024

Impaired cognitive ability is one of the most frequently reported neuropsychiatric symptoms in post-COVID phase among patients. It unclear whether this condition related to structural or functional brain changes.

Language: Английский

Citations

1
Limbic system damage following SARS-CoV2 infection DOI Creative Commons
Aslihan Taskiran-Sağ,

Hare Yazgi

Brain Communications, Journal Year: 2023, Volume and Issue: 5(6)

Published: Jan. 1, 2023

The World Health Organization declared end to COVID-19 pandemic on May 5, 2023.Certainly, this did not mean that SARS-CoV2 would be a concern in our daily medical practice.As neurologists, we may even have seen the major neurological disease burden caused by virus regarding long-term sequelae survivors.SARS-CoV2 is neurotropic virus.Although direct evidence present, thought enter neural tissue either hematogenously or through peripheral nerve endings and access brain via retrograde transport.The symptoms of long COVID arise from invasion (1).There was remarkable research article Brain Communications June 2023 Thomasson et al. limbic system damage following infection (2).They delicately showed moderately severely affected patients displayed impaired emotion recognition which also associated with decreased memory olfactory abilities.Moreover, they identified altered functional connectivity patterns involving cortico-subcorticalcerebellar networks at 6-9 months post-infection.From very beginning, has been under spotlight since loss olfaction one presenting infection.Subsequent studies shown metabolism, perfusion, structure structures after .This study adds these data showing behavioral consequences changes simultaneously, COVID-19.The main question wonder about point whether there were accompanying structural sites brain.The authors tried assess issue volume-based morphometric (VBM) analyses.They reported no differences anatomical images could patterns.We like out absence control group makes it difficult

Language: Английский

Citations

3
COVID-19: ramifications of the pandemic on mental health and substance abuse DOI Creative Commons
Bala Munipalli, Majd Al‐Soleiti,

Anjali Morris

et al.

Frontiers in Public Health, Journal Year: 2024, Volume and Issue: 12

Published: July 31, 2024

To explore the ramifications of COVID-19 pandemic on Mental Health and Substance Use.

Language: Английский

Citations

0
Transient MRI changes and neurological deterioration in glioblastoma upon SARS-CoV-2 infection DOI Creative Commons
Thomas Zeyen, Lea L. Friker, Daniel Paech

et al.

Journal of Cancer Research and Clinical Oncology, Journal Year: 2024, Volume and Issue: 150(9)

Published: Sept. 28, 2024

Language: Английский

Citations

0
Cognitive Function and Brain Structure in COVID-19 Survivors: The Role of Persistent Symptoms DOI Creative Commons
Krupa Vakani, Ray Norbury, Martina Vanova

et al.

Behavioural Brain Research, Journal Year: 2024, Volume and Issue: 476, P. 115283 - 115283

Published: Oct. 3, 2024

Persistent COVID-19 symptoms post-acute state have been shown to a significant negative impact on brain structure and function. In this study, we conducted magnetic resonance imaging (MRI) of the whole in 43 working-age adults (mean age: 44.79±10.80; range: 24-65 years) with history (731.17±312.41 days post-diagnosis), also assessed their cognitive function (processing speed, attention, working memory, executive function, recognition memory), mental health, sleep quality. MRI data were processed using FSL derive regional volumes for bilateral nucleus accumbens, caudate, pallidum, putamen, thalamus, amygdala, hippocampus, total grey matter, white cerebral spinal fluid volume, analysed relation persistent symptom load, Higher load was significantly associated smaller putamen lower response accuracy memory tasks, as well longer time complete task, poorer health Smaller fully mediated relationship between Further research is required confirm whether reduced volume its association poor persists survivors long term.

Language: Английский

Citations

0