Key engineering materials,
Journal Year:
2024,
Volume and Issue:
1005, P. 43 - 48
Published: Dec. 24, 2024
This
study
investigates
the
medicinal
potential
of
proteins
derived
from
Phallus
indusiatus
,
commonly
known
as
bamboo
mushroom,
focusing
on
their
bioactive
properties
mushroom
proteins,
including
antioxidant,
anticancer
and
anti-inflammatory
effects.
Using
a
non-solvent
extraction
method,
crude
were
isolated
purified
through
anion-exchange
chromatography.
After
stepwise
NaCl
elution,
distinct
eluted
peaks
collected,
designated
P1-P4
fraction.
Each
protein
fractions
primarily
demonstrated
moderate
antioxidant
activity.
Bioactivity
assessments
further
conducted
several
(P1,
P2,
P3,
P4)
using
LPS-stimulated
RAW264.7
cells
to
evaluate
properties.
The
results
revealed
that
P1,
P4
significantly
reduced
nitric
oxide
production,
with
demonstrating
most
potent
effect.
As
results,
would
be
exhibited
Fungal
Immunomodulatory
Proteins
(FIPs)
selective
activity,
suggesting
for
therapeutic
applications.
Anticancer
activity
was
assessed
against
A549,
where
all
notable
cytotoxicity
cancer
cell,
without
affecting
normal
Vero
cells.
These
findings
highlight
P.
containing
pharmacological
developing
mushroom-based
meat
analogs.
Future Foods,
Journal Year:
2024,
Volume and Issue:
9, P. 100359 - 100359
Published: April 30, 2024
Significant
attention
is
focused
on
mushrooms
and
mushroom
protein
hydrolysates
owing
to
their
sustainability
nutritional
profile
with
different
uses
in
diverse
industries.
This
review
examines
the
composition,
functional
properties,
production
methods
applications
of
hydrolysates.
It
commenced
a
brief
overview
where
importance
food,
pharmaceutical,
cosmetic,
agricultural
industries
were
explored.
The
significance
as
alternatives
animal
proteins
applicable
producing
was
discussed.
Methods
including
conventional
(chemical
enzymatic)
extraction,
ultrasound-assisted
microwave-assisted
extractions
used
extract
during
Using
enzymeassisted-
ultrasound-extraction
enhance
extraction
efficiency
exclusively
highlighted
promising
technique.
To
obtain
enhanced
yield
quality,
desired
characteristics,
crucial
factors
consisting
pH,
temperature,
time,
solvent
type,
enzyme
concentration
ratio-ofsubstrate-
need
be
optimized.
physicochemical
properties
are
summarized.
Variability
species,
efficiency,
selection
cost,
standardization,
consumer
perception
which
constitute
challenges
limitations
for
application
addressed.
Research
should
conducted
optimize
hydrolysis
processes
explore
new
species.
Biomedicines,
Journal Year:
2024,
Volume and Issue:
12(7), P. 1483 - 1483
Published: July 4, 2024
For
centuries,
humans
have
used
mushrooms
as
both
food
and
pro-health
supplements.
Mushrooms,
especially
those
related
to
the
functions
of
human
immune
system,
are
rich
in
dietary
fiber,
minerals,
essential
amino
acids,
various
bioactive
compounds
significant
health-promoting
properties.
Immunoregulatory
include
lectins,
terpenes,
terpenoids,
polysaccharides,
fungal
immunomodulatory
proteins
(FIPs).
The
distribution
these
varies
from
one
species
mushroom
another,
their
activities
depend
on
core
structures
chemical
modifications
composition
fractions.
In
this
review,
we
describe
active
medical
mushrooms.
We
summarize
potential
mechanisms
for
vitro
vivo
detail
approaches
developing
applying
Finally,
discuss
applications
peptides
highlight
areas
that
require
improvement
before
widespread
use
therapeutic
agents
explore
status
clinical
studies
products,
well
prospect
application
AMPs
‘drug-like’
with
great
treatment
non-healing
chronic
wounds
multiresistant
infections.
Fermentation,
Journal Year:
2024,
Volume and Issue:
10(6), P. 275 - 275
Published: May 23, 2024
It
is
widely
known
that
mushrooms
present
several
properties
with
applications
in
the
medicinal
and
pharmaceutical
sectors,
including
antimicrobial,
immunomodulatory,
antioxidant,
hypotensive,
neuroprotective,
anti-inflammatory
activities.
This
article
aims
to
review
examples
of
bioactive
metabolites
responsible
for
those
activities,
such
as
polysaccharides,
phenols
polyphenols,
terpenes,
peptides,
alkaloids,
steroids,
which
are
produced
by
relevant
mushroom
species.
also
discusses
their
production
through
solid-state
fermentation
submerged
fermentation,
well
processes
obtention
extracts
considerations
on
stability
aiming
industrial
applications.
In
addition,
examines
patent
landscape
surrounding
mushroom-derived
bioactives,
shedding
light
intellectual
property
history
innovations
driving
this
field
forward.
Examples
recently
deposited
patents
highlighted,
main
depositors.
China
United
States
major
depositor
countries
(52%
35%
patents,
respectively),
principal
compounds
polysaccharides
alkaloids.
The
provides
insights
into
current
market
landscape,
showcasing
products
available
consumers.
From
dietary
supplements
skincare
formulations,
offerings
reflect
growing
interest
harnessing
health
benefits
bioactives.
Molecules,
Journal Year:
2024,
Volume and Issue:
29(14), P. 3393 - 3393
Published: July 19, 2024
Hypsizygus
marmoreus
has
abundant
proteins
and
is
a
potential
source
for
the
development
of
bioactive
peptides.
However,
currently,
research
on
components
H.
mainly
focuses
polysaccharides,
there
no
relevant
preparation
In
this
article,
an
ultrasound-assisted
extraction
method
was
used
to
extract
from
marmoreus,
then,
four
peptides
with
different
molecular
weight
ranges
were
prepared
through
protease
hydrolysis
classification.
The
antioxidant
antibacterial
activities
also
studied.
Under
optimal
conditions,
rate
53.6%.
Trypsin
exhibited
highest
proteins.
parameters
enzymatic
substrate
concentration
3.7%,
enzyme
addition
5700
U/g,
pH
value
7,
temperature
55
°C,
time
3.3
h.
these
peptide
yield
59.7%.
types
by
grading.
Among
them,
low
(<1
kDa)
had
stronger
activities.
This
study
provides
theoretical
basis
efficient
products.
ABSTRACT
Mushrooms
have
long
been
an
integral
part
of
human
culture
and
health
are
valued
for
their
nutritional
therapeutic
properties.
Often
referred
to
as
a
superfood,
mushrooms
rich
in
bioactive
compounds
that
provide
range
benefits
including
antioxidant,
antimicrobial,
anticancer,
prebiotic,
antidiabetic,
anti‐inflammatory
effects.
This
review
focussed
on
the
diversity
mushrooms,
emphasizing
medicinal
significance,
explores
secondary
metabolites
with
potential
applications
nutraceuticals
pharmaceuticals.
It
underscores
role
vital
agents
developing
value‐added
products.
An
overview
compounds,
such
polysaccharides,
peptides,
proteins,
terpenoids,
phenolic
identified
numerous
mushroom
species.
Additionally,
addresses
advancements
fungal
biotechnology,
particularly
use
fungi
efficient
industrial
cell
factories,
influence
food
quality
sustainability.
By
critically
analyzing
recent
studies,
summarizes
diverse
roles
biomolecules
pharmaceutical
industries
highlights
significant
contribution
modern
medicine
health‐related
fields.
International Journal of Radiation Biology,
Journal Year:
2025,
Volume and Issue:
unknown, P. 1 - 11
Published: March 14, 2025
Purpose
This
research
assesses
the
radioprotective
and
antioxidant
activity
of
polysaccharide
(POM)
derived
from
Pleurotus
ostreatus
strain
on
rats
suffering
metabolic
problems
due
to
irradiation.
The
crude
POM
obtained
through
chemical
analysis
was
found
consist
glucose,
galactose,
fructose
in
1:1.2:0.1
ratio
but
absent
uronic
acid,
sulfate.
Moreover,
it
demonstrated
radical
scavenging
(45.21-84.21%)
at
5
mg/ml
concentration.
