Spectroscopic Characterization of the Binding and Release of Hydrophilic, Hydrophobic and Amphiphilic Molecules from Ovalbumin Supramolecular Hydrogels DOI Creative Commons
Ana Vesković, Danica Bajuk–Bogdanović, Vladimir B. Arion

et al.

Gels, Journal Year: 2022, Volume and Issue: 9(1), P. 14 - 14

Published: Dec. 26, 2022

Protein-based hydrogels have attracted growing attention for pharmaceutical and biomedical applications. Ovalbumin (OVA), the hen egg white albumin, possessing good foaming gelling properties being widely used in food industry, has recently been indicated as a potential vehicle. In this study, binding release of pure OVA were investigated by electron paramagnetic resonance (EPR) spin labeling. The comparative analysis between serum albumin (SA) revealed same kinetics hydrophilic 3-carbamoyl-proxyl 3-carboxy-proxyl, suggesting diffusion-dominated small probes from both hydrogel types. results obtained with amphiphilic 16-doxylstearate (16-DS) indicate that OVA, unlike SAs, does not possess specific fatty acid site. However, able to accommodate two-fold excess 16-DS, resulting protein thermally induced conformational changes, confirmed Raman spectroscopy. Similarly, hydrophobic modified paullone ligand HL, which was initially free solution, bound hydrogel. found retain significant amount 16-DS HL after 7-day dialysis physiological saline. observed facilitated amphiphilic/hydrophobic molecules compared their sustained release, demonstrate applicability pharmaceutics.

Language: Английский

In situ generated hemostatic adhesives: From mechanisms of action to recent advances and applications DOI Creative Commons
Luís P. G. Monteiro, João M. M. Rodrigues, João F. Mano

et al.

Biomaterials Advances, Journal Year: 2023, Volume and Issue: 155, P. 213670 - 213670

Published: Nov. 4, 2023

Conventional surgical closure techniques, such as sutures, clips, or skin strips, may not always provide optimal wound and require invasive procedures, which can result in potential post-surgical complications. As result, there is a growing demand for innovative solutions to achieve superior improve patient outcomes. To overcome the abovementioned issues, situ generated hemostatic adhesives/sealants have emerged promising alternative, offering targeted, controllable, minimally procedure wide variety of medical applications. The aim this review comprehensive overview mechanisms action recent advances adhesives, particularly protein-based, thermoresponsive, bioinspired, photocrosslinkable formulations, well design challenges that must be addressed. Overall, aims enhance understanding latest advancements adhesives their action, with objective promoting further research field.

Language: Английский

Citations

4
Fabrication of core–shell beads, hollow capsules, and AuNP-embedded catalytic beads from an ultrasmall peptide hydrogel DOI
Tanushree Das, Saurav Das, Debapratim Das

et al.

Chemical Engineering Journal, Journal Year: 2023, Volume and Issue: 477, P. 147105 - 147105

Published: Nov. 4, 2023

Language: Английский

Citations

4
Smart fluorescent PVA/CS/AV/g-C 3 N 4 QDs hydrogel nanocomposites: synthesis and study of UV absorbance, rheological and self-healing properties DOI
Abbas Madhi, Behzad Shirkavand Hadavand,

Mohammad Hassan Madhi

et al.

Fullerenes Nanotubes and Carbon Nanostructures, Journal Year: 2024, Volume and Issue: 32(9), P. 806 - 816

Published: April 9, 2024

Response to exterior stimulants, such as light and pH also self-healing behavior are the major specifications of smart nanocomposites. This project aims synthesise various weight percentages fluorescent hydrogel nanocomposites using natural bio-friendly materials including polyvinyl alcohol (PVA), corn starch (CS), aloe vera (AV) g-C3N4QDs (PSA/CN). Graphitic carbon nitride quantum dots (g-C3N4QDs or CN) were synthesised by way pyrolysis urea citric acid (CA) blend with 18:1 proportion employing microwave-supported procedure. Next, synthesis properties prepared verified means microscopic electroscopic methods. The strong absorption peaks registered at 230, 290 390 nm confirmed UV ability PSA/CN In response exciting wavelength, these emitted green fluorescence (FL) 505–510 nm. Adding CN (0.25 wt% 0.5 wt%) matrix bred a growth in thermal stability resultant Loading diverse into led rheological features improve. Studies on pH-responsive analyses approved against damages.

Language: Английский

Citations

1
The Self-Organization and Gelation Processes in a Cysteine–Silver Solution Containing Chitosan and an Electrolyte DOI

Герман Романович Зеников,

S. D. Khizhnyak,

А. И. Иванова

et al.

Colloid Journal, Journal Year: 2024, Volume and Issue: 86(3), P. 370 - 380

Published: May 30, 2024

Language: Английский

Citations

1
Spectroscopic Characterization of the Binding and Release of Hydrophilic, Hydrophobic and Amphiphilic Molecules from Ovalbumin Supramolecular Hydrogels DOI Creative Commons
Ana Vesković, Danica Bajuk–Bogdanović, Vladimir B. Arion

et al.

Gels, Journal Year: 2022, Volume and Issue: 9(1), P. 14 - 14

Published: Dec. 26, 2022

Protein-based hydrogels have attracted growing attention for pharmaceutical and biomedical applications. Ovalbumin (OVA), the hen egg white albumin, possessing good foaming gelling properties being widely used in food industry, has recently been indicated as a potential vehicle. In this study, binding release of pure OVA were investigated by electron paramagnetic resonance (EPR) spin labeling. The comparative analysis between serum albumin (SA) revealed same kinetics hydrophilic 3-carbamoyl-proxyl 3-carboxy-proxyl, suggesting diffusion-dominated small probes from both hydrogel types. results obtained with amphiphilic 16-doxylstearate (16-DS) indicate that OVA, unlike SAs, does not possess specific fatty acid site. However, able to accommodate two-fold excess 16-DS, resulting protein thermally induced conformational changes, confirmed Raman spectroscopy. Similarly, hydrophobic modified paullone ligand HL, which was initially free solution, bound hydrogel. found retain significant amount 16-DS HL after 7-day dialysis physiological saline. observed facilitated amphiphilic/hydrophobic molecules compared their sustained release, demonstrate applicability pharmaceutics.

Language: Английский

Citations

5