Introdução:
a
presença
de
sintomas
depressão,
ansiedade
e
ideação
suicida
são
amplamente
descritos
na
literatura
em
pessoas
transgênero
que
apresentam
disforia
gênero.A
gênero
é
uma
categoria
clínica
indica
à
existência
sofrimento
relacionado
incongruência
da
identidade
e/ou
expressão
com
o
atribuído
socialmente
ao
sexo
nascimento
do
indivíduo.A
condição
tem
como
consequência
busca
por
mudanças
corporais
obtidas
hormonioterapia
procedimentos
cirúrgicos
afirmação
gênero,
tal
Genitoplastia
Feminizante
(GF)
mulheres
transgênero.Objetivo:
estudo
investigou
transgênero,
apresentem
estão
aguardando
realização
GF
ou
já
realizaram
procedimento.Casuística
Método:
38
participaram
estudo.Realizou-
European Journal of Plastic Surgery,
Journal Year:
2025,
Volume and Issue:
48(1)
Published: Jan. 21, 2025
Abstract
Background
Globally,
the
number
of
individuals
identifying
as
transgender
and
gender-diverse
[TGD]
has
grown
in
last
decade.
This
study
aimed
to
perform
a
Danish
linguistic
translation
cultural
adaptation
GENDER-Q,
new
patient-reported
outcome
measure
[PROM]
designed
evaluate
outcomes
gender-affirming
care.
Methods
The
field
test
version
GENDER-Q
(959
items)
was
translated
into
using
guidelines
from
International
Society
Pharmacoeconomics
Outcomes
Research
World
Health
Organization
ensure
accuracy,
relevance,
validity.
included
two
forward
translations,
backward
translation,
an
expert
panel
meeting,
rounds
patient
cognitive
interviews.
Results
translations
resulted
revisions
142
items,
which
were
then
harmonized
form
version.
A
comparison
back
original
questionnaire
led
total
43
changes
items
response
options.
revised
reviewed
meeting
minor
made
with
28
participants
debriefing
proofread,
resulting
GENDER-Q.
Conclusions
culturally
adapted
for
use
TGD
adult
population.
potential
enhance
understanding
improvement
treatment
health-related
quality-of-life
adults
seeking
Level
Evidence:
Not
gradable.
Expert Review of Neurotherapeutics,
Journal Year:
2025,
Volume and Issue:
unknown, P. 1 - 21
Published: Feb. 27, 2025
Introduction
The
phenomenology
of
depression
is
characterized
by
a
wide
array
emotional,
cognitive,
and
physical
symptoms
that
significantly
disrupt
an
individual's
life.
Societal
changes,
driven
technological
advancements,
economic
pressures,
environmental
concerns
including
climate
change,
shifting
cultural
norms,
have
influenced
how
manifests
understood.
These
developments
led
to
the
identification
new
subtypes,
highlighting
need
for
personalized
treatment
approaches
based
on
individual
underlying
causes.
Pilot and Feasibility Studies,
Journal Year:
2025,
Volume and Issue:
11(1)
Published: April 23, 2025
Negative
experiences
related
to
eating
and
appearance
(NEREAs),
such
as
critical
commentary
from
parents
about
food,
are
common
associated
with
depression
disordered
eating.
Imagery
rescripting
(IR)
is
a
therapeutic
process
during
which
individuals
guided
through
recalling
bringing
support
into
distressing
memories,
like
NEREAs.
Single
sessions
of
IR
demonstrate
promise
in
shifting
the
primary
negative
consequences
NEREAs
clinical
samples
women.
The
objectives
this
pilot
trial
were
evaluate
feasibility
acceptability
remote-delivered,
single
session
nutrition
education
control
group
community
sample
adults
In
parallel
two-arm
trial,
participants
completed
an
in-person
baseline
visit,
one
single-session
intervention
(IR
or
attention-matched
control),
1-
3-month
follow-up
visits
between
February
2023
April
2024
Oregon,
USA.
Markers
included
recruitment,
visit
survey
completion
rates,
fidelity;
was
evaluated
using
participant
feedback
instances
adverse
events.
One
hundred
phone
screen;
96%
reported
at
least
NEREA.
Most
these
ineligible
because
they
met
psychiatric
disorder
criteria
and/or
taking
medication
known
influence
mood
appetite.
Thirty-two
study
visit;
89%
(N
=
27;
mean
age
[SD]
32.52
[15.78],
range
18-73;
56%
cisgender
women;
74.1%
non-Hispanic
White,
14.8%
Asian,
11.1%
Hispanic/Latine,
7.4%
Black,
3.7%
multiracial)
randomly
assigned
(using
random
number
generator)
condition
(13
IR,
14
control).
Curriculum
adherence,
on
average,
94%
for
97%
control.
One-month
retention
82%,
59%.
Post-intervention
ratings
indicated
good
both
arms.
No
events
occurred.
delivered
interventions
feasible
acceptable
men
such,
future
definitive
recommended.
Additional
strategies
increasing
needed.
Single-session
interventions,
have
potential
high
impact
reach.
They
inherently
flexible
cost-effective
that
can
be
across
systems
care,
while
remote
delivery
mitigates
concerns
stigma
access.
ClinicalTrial.gov,
NCT06610318
.
Registered
23
September
2024-retrospectively
registered.
JAMA Network Open,
Journal Year:
2025,
Volume and Issue:
8(4), P. e257115 - e257115
Published: April 24, 2025
Importance
Mental
and
somatic
health
is
often
impaired
among
transgender
persons.
Studies
regarding
coexisting
mental
outcomes
persons
are
limited.
Objective
To
assess
diagnoses
medicine
use
compared
with
cisgender
controls.
Design,
Setting,
Participants
This
register-based
national
cohort
study
included
data
from
January
1,
2000,
to
December
31,
2021.
Transgender
were
on
the
first
date
of
receipt
a
identity
contact
code.
Controls
10
age-matched
men
(n
=
5)
women
for
each
person.
Statistical
analyses
conducted
September
2024.
Main
Outcomes
Measures
The
main
International
Classification
Diseases
Related
Health
Problems,
Tenth
Revision
diagnosis
codes
in
5-year
period
up
code
most
commonly
occurring
physical
illnesses.
determined
after
collection.
Results
3812
(1993
transmasculine
[52.3%]
median
age
19
years
[IQR,
15-24
years]
1819
transfeminine
[47.7%]
23
19-33
years])
38
120
odds
was
12
times
higher
Among
persons,
neurotic,
stress-related
disorders
(transmasculine:
adjusted
ratio
[AOR],
4.70
[95%
CI,
4.02-5.50];
transfeminine:
AOR,
5.27
4.28-6.49]);
developmental
disorders,
including
autism
11.67
8.85-15.39];
9.39
7.05-12.50]);
mood
(affective)
5.41
4.32-6.77];
5.61
4.16-7.57]);
behavioral
4.50
3.61-5.62];
4.15
3.19-5.39])
frequent
controls
opposite
sex
at
birth.
Transmasculine
had
diabetes
(AOR,
2.00
1.12-3.56]),
asthma
(including
chronic
obstructive
lung
disease;
1.40
1.06-1.85]),
injury
poisoning
1.28
1.15-1.41]),
pain
1.29
1.12-1.49])
control
women.
infection
1.68
1.33-2.13]),
anemia
3.08
1.36-6.97]),
1.95
1.25-3.05]),
sleep
apnea
3.41
1.84-6.31]),
1.31
1.08-1.58])
more
men.
psychopharmacologic
medicine,
antacids,
laxatives
(transmasculine
vs
women,
antipsychotics:
6.20
5.07-7.59];
hypnotics-sedatives:
4.45
3.78-5.23];
antacids:
1.25
1.07-1.45];
laxatives:
1.53
1.17-1.99];
men,
4.74
3.92-5.74];
3.01
2.53-3.57];
1.32
1.12-1.56]).
drugs
diseases.
Conclusions
Relevance
Danish
found
significantly
risks
Coexistence
could
be
associated
stress
encountered
due
belonging
gender
or
sexual
orientation
minority
group;
morbidity
should
considered
an
integrated
part
care.
Frontiers in Pain Research,
Journal Year:
2025,
Volume and Issue:
6
Published: April 24, 2025
Pain
is
an
unpleasant
and
unavoidable
part
of
the
human
experience,
but
prevalence
impact
pain
disproportionately
impacts
marginalized
groups,
including
transgender
gender-diverse
people.
While
there
are
many
bases
pain,
psychosocial
variables,
cognitions
(e.g.,
outcome
interpersonal
expectations,
social
gender
norms),
affect
negative
affectivity,
emotional
distress),
factors
exclusion)
may
be
particularly
relevant
in
experiences
individuals.
The
coalescence
these
discussed
this
review,
where
authors
specifically
consider
how
cognitive,
affective,
contribute
to
disparities
seen
Patient-centered
communication
presented
as
a
potential
avenue
directly
mitigate
effect
variables
on
individuals
by
reducing
feelings
exclusion
patients
experience
medical
office,
call
for
additional
experimental
research
development
educational
interventions
providers.
The Journal of Clinical Endocrinology & Metabolism,
Journal Year:
2024,
Volume and Issue:
109(12), P. 3076 - 3086
Published: May 21, 2024
Gender-affirming
care
could
be
associated
with
higher
employment
rate.
We
assessed
rates
in
transgender
persons
compared
to
controls
and
demographic,
health,
treatment-related
factors
persons.