Brazilian Journal of Microbiology, Journal Year: 2025, Volume and Issue: unknown
Published: May 2, 2025
Language: Английский
JAMA Network Open, Journal Year: 2024, Volume and Issue: 7(4), P. e247125 - e247125
Published: April 18, 2024
Respiratory syncytial virus (RSV) resurgences have been noted following the COVID-19 pandemic in many countries. Recent findings suggest that 2021 and 2022 RSV seasons were more severe than past seasons, age distribution may shifted toward older children younger 5 years group.
Language: Английский
Citations
16
The Italian Journal of Pediatrics/Italian journal of pediatrics, Journal Year: 2024, Volume and Issue: 50(1)
Published: Feb. 13, 2024
Abstract Background The coronavirus 2019 (COVID-19) related containment measures led to the disruption of all virus distribution. Bronchiolitis-related hospitalizations shrank during 2020–2021, rebounding pre-pandemic numbers following year. This study aims describe trend in bronchiolitis-related hospitalization this year, focusing on severity and viral epidemiology. Methods We conducted a retrospective investigation collecting clinical records data from infants hospitalized for bronchiolitis winter (1st September-31th March) September 2018 March 2023 six Italian hospitals. No trial registration was necessary according authorization no.9/2014 law. Results Nine hundred fifty-three were last winter, 563 2021–2022, 34 395 2019–2020 483 2018–2019. mean length stay significantly longer year compared previous years (mean 7.2 ± 6 days 2022–2023), 5.7 4 5.3 6.4 5 5.5 2018–2019 ( p < 0.001), respectively. More patients required mechanical ventilation 38 (4%), (1%) 0 11 (2%) 0.05), High-flow nasal cannula non-invasive respiratory supports statistically more common = 0.001 or less). RSV prevalence distribution did not differ but coinfections prevalent 307 (42%), 138 (31%) 1 (33%) 68 (23%) 2019–2020, 61 (28%) 0.001). Conclusions shows growth nearly 70% hospitalisations bronchiolitis, an increase invasive support coinfections, suggesting severe disease course five years.
Language: Английский
Citations
10
Antiviral Research, Journal Year: 2024, Volume and Issue: 223, P. 105823 - 105823
Published: Feb. 6, 2024
Language: Английский
Citations
8
PLoS ONE, Journal Year: 2024, Volume and Issue: 19(2), P. e0285892 - e0285892
Published: Feb. 9, 2024
Background Following the low incidence rates of non-SARS-CoV-2 respiratory viruses registered during strict lockdown enforced in pandemic, a resurgence several endemic Catalonia (Spain) was noted early summer 2021. Objectives In this study, we investigated whether circulation Catalonia, assessed by Microbiological Reporting System (MRSC) and Epidemiological Surveillance Network affected measures, as well as, implication Coronavirus Disease 19 (COVID-19) de-escalation process late season outbreaks 2020–2021 season. Study design A retrospective comparison epidemic patterns viruses’ incidence, using regional public health surveillance data from MRSC, performed between weeks 26/2016 to week 27/2021. Data were expressed weekly total number test positivity for individual viruses. segmented negative binomial regression model conducted, with two parameters included (level trend) each segment time series (2020 pre-lockdown, 2020 post-lockdown 2021). Results reported unit changed lockdown. 51588 confirmed cases different analysis, majority influenza (63.7%). An immediate reduction observed after COVID-19 outbreak human adenovirus virus (HAdV) (β2 = -2.606; P <0.01), parainfluenza (HPIV) -3.023; (IFV) -1.259; but not syncytial (RSV), where remained unchanged. During 2020, significant trend found RSV (β3 -0.170, positive HAdV 0.075, <0.01). 2021, also all viruses, borderline non-significant HPIV -0.027; 0.086). Moreover, trends viral pathogen, except season, close zero. The increased activity their start particularly children under 6 years old. Conclusions Our only provides evidence that occurrence infections taken against SARS-CoV-2 it shows seasonal following relaxation COVID-19-targeted non-pharmaceutical interventions.
Language: Английский
Citations
8
Frontiers in Microbiology, Journal Year: 2024, Volume and Issue: 15
Published: April 2, 2024
Background Respiratory syncytial virus (RSV) is a common cause of upper and lower respiratory tract infections. This study aimed to explore the prevalence other viruses in Bulgaria, characterize genetic diversity RSV strains, perform amino acid sequence analyses surface internal proteins. Methods Clinical epidemiological data nasopharyngeal swabs were prospectively collected from patients with acute infections between October 2020 May 2023. Real-time PCR for 13 viruses, whole-genome sequencing, phylogenetic, performed. Results included three epidemic seasons (2020–2021, 2021–2022, 2022–2023) week 40 previous year 20 following year. Of 3,047 examined, 1,813 (59.5%) tested positive at least one viral pathogen. was second most detected (10.9%) after SARS-CoV-2 (22%). Coinfections 68 cases, including 14 SARS-CoV-2. After two low circulation, activity increased significantly during 2022–2023 season. The detection rates 3.2, 6.6, 13.7% first, second, third seasons, respectively. found children under 5 years old bronchiolitis (40%) pneumonia (24.5%). RSV-B drove epidemic. Phylogenetic analysis indicated that sequenced strains belonged GB5.0.5a GB5.0.6a genotypes. Amino substitutions proteins, F protein antigenic sites identified compared BA prototype strain. Conclusion revealed strong resurgence autumn 2022 lifting anti-COVID-19 measures, leading role as causative agent serious illnesses early childhood, relatively circulating strains.
Language: Английский
Citations
8
Open Forum Infectious Diseases, Journal Year: 2024, Volume and Issue: 11(5)
Published: April 25, 2024
Abstract Varied seasonal patterns of respiratory syncytial virus (RSV) have been reported worldwide. We conducted a systematic review on articles identified in PubMed reporting RSV seasonality based data collected before 1 January 2020. were examined by geographic location, calendar month, analytic method, and meteorological factors including temperature absolute humidity. Correlation regression analyses to explore the relationship between study methods characteristics locations. seasons 209 published 1973–2023 for 317 locations 77 countries. Regular similarly countries temperate regions, with highly variable subtropical tropical Longer durations associated higher daily average mean The global provided important information optimizing interventions against infection.
Language: Английский
Citations
6
Human Vaccines & Immunotherapeutics, Journal Year: 2024, Volume and Issue: 20(1)
Published: Aug. 19, 2024
Respiratory syncytial virus (RSV) is an important cause of respiratory illness. While most attention paid to childhood infection, the RSV burden in adults ≥60 y should also be considered. In Brazil, this generally underrecognized, where greater focus toward other pathogens. This article presents insights from a multidisciplinary panel gathered review epidemiologic data and current diagnostic approaches Brazil (and their limitations) develop communication strategies improve knowledge awareness. National surveillance indicate steady increase cases RSV-related severe acute illness (RSV-SARI) those aged recent years, with high fatality rates (>30%). Routine testing older individuals symptoms relatively low. Educational activities targeted health-care professionals general public are critical raising awareness importance individuals, particularly as protective vaccines now available.
Language: Английский
Citations
6
Vaccines, Journal Year: 2023, Volume and Issue: 11(2), P. 412 - 412
Published: Feb. 10, 2023
Seasonal epidemics of respiratory viruses, syncytial virus (RSV), influenza parainfluenza viruses (PIVs), and human metapneumovirus (MPV) are associated with a significant healthcare burden secondary to hundreds thousands hospitalizations every year in the United States (US) alone. Preventive measures implemented reduce spread SARS-CoV-2 (COVID-19 infection), including facemasks, hand hygiene, stay-at-home orders, closure schools local/national borders may have impacted transmission these viruses. In this study, we looked at hospitalization mortality trends for various viral infections from January 2017 December 2020. We found strong reduction all infections, lowest admission rates last season (2020) compared corresponding months past three years (2017–2019). This study highlights importance public health interventions during COVID-19 pandemic, which had far-reaching benefits. Appropriate timely use help severity future seasonal outbreaks as well their on already strained systems.
Language: Английский
Citations
16
Scientific Reports, Journal Year: 2023, Volume and Issue: 13(1)
Published: Nov. 21, 2023
In 2022, many regions around the world experienced a severe respiratory syncytial virus (RSV) epidemic with an earlier-than-usual start and increased numbers of paediatric patients in emergency departments. Here we carried out this study to describe epidemiology genetic characteristics RSV infection hospitalized acute infections 2022. Samples were tested for by multiplex real time reverse transcription polymerase chain reaction. Subsequently, subset positive samples was selected NGS sequencing. detected 16.04%, among which RSV-A confirmed 7.5% RSV-B 76.7%. more identified infants aged ≤ 11 months (83.3%) shift circulation pattern observed, highest incidences between September-November. Phylogenetic analyses revealed that all strains belonged GA2.3.5 genotype GB5.0.5a genotype. Three putative N-glycosylation sites at amino acid positions 103, 135, 237 predicted strains, while four N-linked glycosylation 81, 86, 231 294 strains. Globally, our findings reveal exclusive co-circulation two lineages within pediatric population Senegal, especially months.
Language: Английский
Citations
15
Virology Journal, Journal Year: 2023, Volume and Issue: 20(1)
Published: Jan. 9, 2023
Abstract Background Under the pressure of non-pharmaceutical interventions (NPIs) targeting severe acute respiratory syndrome coronavirus 2, prevalence human adenovirus (HAdV) was monitored before and after NPIs launched on Jan 24, 2020 in pediatric patients Beijing, China. Methods Respiratory samples collected from children hospitalized with infections 2015 to Dec 2021 were screened by direct immunofluorescence test or capillary electrophoresis-based multiplex PCR assay. The hexon, penton base, fiber genes amplified HAdV positive specimens, then sequenced. For typing, phylogenetic trees built MEGA X. Then clinical data cases collected. All evaluated using SPSS Statistics 22.0 software. Results A total 16,097 enrolled 466 (2.89%, 466/16,097) HAdV-positive. rates varied, ranging 4.39% (151/3,438) 2018 to1.25% (26/2,081) 2021, dropped 3.19% (428/13,408) 1.41% (38/2,689) ( P < 0.001). There 350 typed into nine types species B, C, E 34 recorded as undetermined. Among them, HAdV-B3 (51.56%, 198/384) most prevalent 2017, HAdV-B7 (29.17%, 112/384) co-circulated 2019. After launched, B7 decreased sharply undetected while HAdV-C1 became dominant one undetermined more. Conclusions endemic pattern changed Beijing because for COVID-19. Especially, HAdV-B HAdV-C.
Language: Английский
Citations
13