Phthalate exposure and the metabolic syndrome: A systematic review and meta-analysis DOI Creative Commons
Diana María Mérida, Belén Moreno‐Franco, Montse Marquès

et al.

Environmental Pollution, Journal Year: 2023, Volume and Issue: 333, P. 121957 - 121957

Published: June 15, 2023

Phthalates are chemicals widely used in plastic-based consumer products, and human exposure is universal. They classified as endocrine disruptors, specific phthalate metabolites have been associated with an increased risk of cardiometabolic diseases. The aim this study was to assess the association between metabolic syndrome general population. A comprehensive literature search performed four databases (Web Science, Medline, PubMed, Scopus). We included all observational studies that evaluate available until January 31st, 2023. Pooled Odds Ratios (OR) their 95% confidence intervals were calculated by using inverse-variance weighted method. Nine cross-sectional 25,365 participants aged from 12 80 included. Comparing extreme categories exposure, pooled ORs for were: 1.08 (95% CI, 1.02-1.16, I2 = 28%) low molecular weight phthalates, 1.11 1.07-1.16, 7%) high phthalates. For individual metabolites, achieved statistical significance 1.13 1.00-1.27, 24%) MiBP; 1.89 1.17-3.07, 15%) MMP men; 1.12 1.00-1.25, 22%) MCOP; 1.09 0.99-1.20, 0%) MCPP; 1.16 1.05-1.28, 6%) MBzP; 1.09-1.24, 14%) DEHP (including ΣDEHP its metabolites). In conclusion, both phthalates 8 11% higher prevalence MetS, respectively. six a MetS.

Language: Английский

Nano and microplastics occurrence in wastewater treatment plants: A comprehensive understanding of microplastics fragmentation and their removal DOI Creative Commons
Sirajum Monira, Rajeev Roychand, Faisal I. Hai

et al.

Chemosphere, Journal Year: 2023, Volume and Issue: 334, P. 139011 - 139011

Published: May 23, 2023

Nano/microplastic (NP/MP) pollution is a growing concern for the water environment. Wastewater treatment plants (WWTPs) are considered major recipients of MP before discharging into local waterbodies. MPs enter WWTPs mainly from synthetic fibers through washing activities and personal care products. To control prevent NP/MP pollution, it essential to have comprehensive understanding their characteristics, fragmentation mechanisms, effectiveness current processes used in removal. Therefore, objectives this study (i) understand detailed mapping WWTP, (ii) mechanisms NP, (iii) investigate removal efficiency by existing WWTP. This found that fiber dominant shape MP, polyethylene, polypropylene, polyethylene terephthalate, polystyrene polymer type wastewater samples. Crack propagation mechanical breakdown due shear forces induced facilities (e.g., pumping, mixing, bubbling) could be causes NP generation Conventional ineffective complete MPs. Although these capable removing ∼95% MPs, they tend accumulate sludge. Thus, significant number may still released environment on daily basis. suggested using DAF process primary unit can an effective strategy initial stage goes secondary tertiary stage.

Language: Английский

Citations

52

Origin, dietary exposure, and toxicity of endocrine-disrupting food chemical contaminants: A comprehensive review DOI Creative Commons
Leila Peivasteh-Roudsari,

Raziyeh Barzegar-Bafrouei,

Kurush Aghbolagh Sharifi

et al.

Heliyon, Journal Year: 2023, Volume and Issue: 9(7), P. e18140 - e18140

Published: July 1, 2023

Endocrine-disrupting chemicals (EDCs) are a growing public health concern worldwide. Consumption of foodstuffs is currently thought to be one the principal exposure routes EDCs. However, alternative ways human through inhalation and dermal contact. These compounds in food products such as canned food, bottled water, dairy products, fish, meat, egg, vegetables ubiquitous general population. Therefore, understanding EDCs' properties, origin, exposure, toxicological impact, legal aspects vital control their release environment food. The present paper provides an overview EDCs possible disrupting impact on endocrine system other organs.

Language: Английский

Citations

47

Occurrence of phthalates in different food matrices: A systematic review of the main sources of contamination and potential risks DOI

Júlia Moraes da Costa,

Lilian Seiko Kato, Diego Galvan

et al.

Comprehensive Reviews in Food Science and Food Safety, Journal Year: 2023, Volume and Issue: 22(3), P. 2043 - 2080

Published: March 29, 2023

This systematic review aimed to investigate the occurrence of phthalates (phthalic acid esters [PAEs]) in different food matrices, as well report main sources PAEs food, potential risks population, and factors that influence its migration from contact materials (FCMs) food. Nineteen were identified, including di-(2-ehtylhexyl) phthalate (DEHP), dibutyl-phthalate (DBP), benzylbutyl (BBP), diisononyl (DINP), diisodecyl (DIDP) fruits vegetables, milk dairy products, cereals, meat, fish, fat oils, snacks, condiments sauces, miscellaneous, baby Fifty-seven values above legal limits countries. DEHP is PAE with highest incidence, maximum concentrations specific limit (SML) for oils fats, vegetables. The risk exceeding tolerable daily intake (TDI) was high DBP products children adults. Fat are most critical DEHP, DBP, BBP, DINP. Comparing estimated (EDI) TDI, there a "milk products" adults "cereal cereal concerning DEHP. "Cereal presented DBP. "fat oils" category about Temperature, time between FCM, percent, acidity positively correlate PAE's migration. contamination occurs many steps production chain.

Language: Английский

Citations

45

Global environmental and toxicological data of emerging plasticizers: current knowledge, regrettable substitution dilemma, green solution and future perspectives DOI
Abdul Qadeer, Muhammad Yunus Anis, Genoa R. Warner

et al.

Green Chemistry, Journal Year: 2024, Volume and Issue: 26(10), P. 5635 - 5683

Published: Jan. 1, 2024

The global plasticizer market is projected to increase from $17 billion in 2022 $22.5 2027.

Language: Английский

Citations

32

Recent applications of chromatography for determining microplastics and related compounds (bisphenols and phthalate esters) in food DOI Creative Commons
Beatriz Martín-Gómez, J. Stephen Elmore, Silvia Valverde

et al.

Microchemical Journal, Journal Year: 2024, Volume and Issue: 197, P. 109903 - 109903

Published: Jan. 4, 2024

The presence of microplastics in food poses a significant concern due to its potential impact on human health. Numerous studies have focused spectroscopic techniques identify and confirm those contaminants food, but less attention has been paid chromatographic techniques. Thus, this article provides comprehensive review the recent applications analysis related compounds such as bisphenols phthalate esters from 2018 2022. study covers discusses range different (gas liquid chromatography). Furthermore, also explores sample treatments employed for extracting these matrices, while offering detailed their principles, advantages, disadvantages. This readers with an overview valuable insights into analytical performance food.

Language: Английский

Citations

29

Decrease in Sperm Parameters in the 21st Century: Obesity, Lifestyle, or Environmental Factors? An Updated Narrative Review DOI Open Access
Romualdo Sciorio, Luca Tramontano,

Mohammed Adel

et al.

Journal of Personalized Medicine, Journal Year: 2024, Volume and Issue: 14(2), P. 198 - 198

Published: Feb. 11, 2024

Semen quality represents a compelling factor for fertility, and delineating the normal values has proven difficult. In last four decades, several authors have reported noticeable decline in sperm parameters. Also, studies investigating ‘time to pregnancy’ shown that fecundity begins be reduced when numbers decrease below 30 million, even though according 6th edition of WHO manual, value is currently 16 million/mL or 39 million per ejaculate. There exists sufficient data suggest counts over time, clear reason this adverse trend not well established, but some associations been hypothesised, such as maternal smoking during pregnancy. Additional potential factors yet fully illustrated involve poor diet, increased obesity, exposure environmental toxins. Moreover, change conditions more common endocrine-disrupting chemicals (EDCs), pesticides herbicides, bisphenol A, phthalates, polychlorinated biphenyls, heavy metals, starting from prenatal life continuing into adulthood, may exhibit probable features explaining reduction Therefore, main goal narrative review furnish an overview possible effects EDCs on testicular function spermatogenesis and, also, summarise evidence regarding examine its consequences.

Language: Английский

Citations

24

Environmental and Food Contamination by Phthalic Acid Esters (PAEs): Overview DOI Creative Commons
Artur Sokołowski, Magdalena Kończak, Patryk Oleszczuk

et al.

Water Air & Soil Pollution, Journal Year: 2024, Volume and Issue: 235(5)

Published: May 1, 2024

Abstract Phthalic acid esters (PAEs) are dialkyl or alkyl/aryl ester derivatives of phthalic acid. PAEs colorless, odorless, and flavorless oily liquids. the main plasticizers used in industry households. DEHP (di-(2-ethyl hexyl) phthalate) is plasticizer polymer industry, whereas DMP (dimethyl DEP (diethyl mainly as solvents fixatives cosmetics personal care products. synthetic organic compounds poorly soluble water but solvents. Into environment, they introduced during production, use degradation, packaging, transportation plastic In degraded three ways: by hydrolysis, photodegradation, microbial biodegradation hydrolysis environment very slow. pollutants soil, water, groundwater, river marine air, sediments, vegetables, biota. Due to great interest subject environmental pollution emergence new information this area, it extremely important systematically review current knowledge. presented paper, occurrence different matrices was reviewed. The toxicity plants, animals, humans also described.

Language: Английский

Citations

17

Profiles of phthalic acid esters (PAEs) in bottled water, tap water, lake water, and wastewater samples collected from Hanoi, Vietnam DOI

Thuy Minh Le,

Ha My Nu Nguyen,

Vy Khanh Nguyen

et al.

The Science of The Total Environment, Journal Year: 2021, Volume and Issue: 788, P. 147831 - 147831

Published: May 19, 2021

Language: Английский

Citations

75

Insights Into the Prevalence and Impacts of Phthalate Esters in Aquatic Ecosystems DOI Creative Commons
Ntsako Dellas Baloyi, Memory Tekere, Khumbudzo Walter Maphangwa

et al.

Frontiers in Environmental Science, Journal Year: 2021, Volume and Issue: 9

Published: July 15, 2021

Phthalate esters (PEs) are by far the most produced and extensively used synthetic organic chemicals with notable applications in many industrial products such as vinyl upholstery, adhesives, food containers, packaging materials, printing inks, cosmetics, paints, pharmaceuticals munitions, insecticides among other. PEs have long been recognised ubiquitous pollutants of prime environmental concern, urbanisation amongst main cause source these compounds. Due to their notoriety, compounds known pose devastating effects living organisms including humans. The presence metabolites aquatic ecosystems is concern primarily due endocrine disrupting carcinogenicity properties. Several research studies reported prevalence, exposure pathways, toxicity, impacts Their principal routes could be direct or indirect, which route include contact, eating, drinking contaminated foods, indirect constitute aerosols, leaching other forms contamination. find way into water systems through means effluent discharges, urban agricultural land runoff, from waste dumps diffuse sources. High-end instrumentation improved methodologies on hand resulted increased ability measure trace levels (μg/L) different matrices ecological compartments lakes, oceans, rivers, sediments, wetlands samples. In light above, this article provides an informed focused information prevalence phthalate related Furthermore, techniques that enabled extraction analysis samples also explained. Future outlooks needs highlighted manuscript. This will better understand temporal spatial distributions aid devising prudent curtail footprints.

Language: Английский

Citations

65

Composting and green technologies for remediation of phthalate (PAE)-contaminated soil: Current status and future perspectives DOI
‬Huu-Tuan Tran, Minh‐Ky Nguyen, Hong-Giang Hoang

et al.

Chemosphere, Journal Year: 2022, Volume and Issue: 307, P. 135989 - 135989

Published: Aug. 18, 2022

Language: Английский

Citations

48