Current data regarding homeostasis of tissues oxygenation in pathophysiological and therapeutic circumstances DOI Creative Commons
Constantin Munteanu, Mihaela Antonina Călin, Dragoș Manea

et al.

Balneo and PRM Research Journal, Journal Year: 2023, Volume and Issue: 14(Vol.14, no.2), P. 565 - 565

Published: June 23, 2023

Oxygen is essential for cellular respiration and energy production. Tissue oxygenation refers to delivering oxygen cells throughout the body. Microcirculation brings blood through small sanguine vessels maintain cells' supply of nutrients oxygen. Optimal tissue microcirculation are maintaining healthy tissue. Conversely, poor can cause damage, impair wound healing, increase infection risk. Several factors affect microcirculation, including age, lifestyle (such as smoking stress), underlying medical conditions diabetes high pressure). To improve individuals engage in habits such regular exercise, eating, stress management, avoiding smoking. also be looked therapeutic, given that topical cosmetic treatments massage, pelotherapy, hydrotherapy, moisturizers, certain skin care products help pro-mote at somatic level. In scientific literature, focus on hypoxia rather than oxygenation. This article proposes a paradigm shift emphasizes homeostatic importance pathophysiological therapeutic circumstances. The systematic review data from last 2 years (2021-2022) meta-analysis performed will contribute practical approach pathology circumscribed Keywords: oxygenation; Hypoxia; Microcirculation; Homeostasis; Microenvironment

Language: Английский

First-mile walking, neighbourhood walkability and physical activity in Bangkok, Thailand DOI Creative Commons

Panitat Ratanawichit,

Sigit D. Arifwidodo,

Rujiroj Anambutr

et al.

Frontiers in Built Environment, Journal Year: 2025, Volume and Issue: 11

Published: April 7, 2025

Introduction First-mile walking (FMW) supports sustainable mobility and public health by enabling utilitarian recreational walking. However, its relationship with neighbourhood walkability physical activity remains underexplored in tropical, high-density cities like Bangkok. This study examines these associations. Methods A cross-sectional survey of 881 Bangkok residents from 50 districts assessed (NEWS-A) (GPAQ). Multivariable logistic regression models examined associations between walkability, FMW, sufficient (≥150 min/week). Results Higher significantly increased both FMW. High-rise were more likely to engage walking, while planned high-rise neighbourhoods supported Utilitarian strongly correlated achieving activity. Conclusion Neighbourhood design plays a critical role promoting Policy efforts should prioritise pedestrian infrastructure, green spaces, transport connectivity encourage active lifestyles.

Language: Английский

Citations

0
From gut to bone: deciphering the impact of gut microbiota on osteoporosis pathogenesis and management DOI Creative Commons

Linjie Hao,

Yuzhu Yan, Guilin Huang

et al.

Frontiers in Cellular and Infection Microbiology, Journal Year: 2024, Volume and Issue: 14

Published: Sept. 25, 2024

Osteoporosis (OP) is characterized by decreased bone mineral density (BMD) and increased fracture risk, poses a significant global health burden. Recent research has shed light on the bidirectional relationship between gut microbiota (GM) health, presenting novel avenue for understanding OP pathogenesis developing targeted therapeutic interventions. This review provides comprehensive overview of GM-bone axis, exploring impact GM development management. We elucidate established risk factors OP, delve into diversity functional changes in OP. Furthermore, we examine experimental evidence clinical observations linking alterations composition or function with variations BMD risk. Mechanistic insights microbial mediators such as metabolites products, are discussed. Therapeutic implications, including GM-targeted interventions dietary strategies, also explored. Finally, identify future directions challenges translating these findings practice.

Language: Английский

Citations

2
Current data regarding homeostasis of tissues oxygenation in pathophysiological and therapeutic circumstances DOI Creative Commons
Constantin Munteanu, Mihaela Antonina Călin, Dragoș Manea

et al.

Balneo and PRM Research Journal, Journal Year: 2023, Volume and Issue: 14(Vol.14, no.2), P. 565 - 565

Published: June 23, 2023

Abstract: Oxygen is essential for cellular respiration and energy production. Tissue oxygenation refers to delivering oxygen cells throughout the body. Microcirculation brings blood through small sanguine vessels maintain cells' supply of nutrients oxygen. Optimal tissue ox-ygenation microcirculation are maintaining healthy tissue. Conversely, poor can cause damage, impair wound healing, increase infection risk. Several factors affect microcirculation, including age, lifestyle (such as smoking stress), underlying medical conditions diabetes high pres-sure). To improve individuals engage in habits such regular exercise, eating, stress management, avoiding smoking. also be looked therapeutic, given that topical cosmetic treatments massage, pelotherapy, hydrotherapy, moisturizers, certain skin care products help promote at somatic level. In scientific literature, focus on hypoxia rather than oxygenation. This article proposes a paradigm shift emphasizes homeostatic importance pathophysiological therapeutic circumstances. The systematic review data from last 2 years (2021-2022) meta-analysis performed will contribute practical approach pathology circumscribed Keywords: oxygenation; Hypoxia; Microcirculation; Homeostasis; Microenvironment

Language: Английский

Citations

6
Associations between Liver Enzymes, Lifestyle Risk Factors and Pre-Existing Medical Conditions in a Population-Based Cross-Sectional Sample DOI Open Access
Onni Niemelä,

Aini Bloigu,

Risto Bloigu

et al.

Journal of Clinical Medicine, Journal Year: 2023, Volume and Issue: 12(13), P. 4276 - 4276

Published: June 26, 2023

While alanine aminotransferase (ALT) and gamma-glutamyltransferase (GGT) enzymes are commonly used indicators of liver dysfunction recent studies have suggested that these may also serve as predictive biomarkers in the assessment extrahepatic morbidity. In order to shed further light on interactions between serum enzyme abnormalities, factors lifestyle health status we examined ALT GGT activities a population-based sample 8743 adult individuals (4048 men, 4695 women from National FINRISK 2002 Study, mean age 48.1 ± 13.1 years) with different levels alcohol drinking, smoking, physical activity, body weight presence or absence various pre-existing medical conditions. The assessments included laboratory tests for inflammation, lipid fatty index (FLI), proxy liver. prevalence abnormalities were significantly influenced by use (ALT: p < 0.0005 men; GGT: <0.0005 both genders), smoking (GGT: =0.002 women), adiposity (p all comparisons), inactivity <0.0005; ALT: <0.05 women) coffee consumption genders; <0.001 men). total sum risk factor scores (LRFS) occurrence rather linear manner. Significantly higher LRFS observed subgroups conditions when compared those having no morbidities <0.0005). logistic regression analyses adjusted factors, associated liver, diabetes hypertension. coronary heart disease, angina pectoris, cardiac insufficiency, cerebrovascular asthma depression. Combinations abnormal increased odds hypertension coinciding FLI. data indicates readily respond unfavorable associating wide array supports close links hepatic open new insights more comprehensive algorithms assessing mechanistically anchored disease

Language: Английский

Citations

4
Predictive risk markers in alcoholism DOI
Onni Niemelä

Advances in clinical chemistry, Journal Year: 2023, Volume and Issue: unknown, P. 113 - 181

Published: Jan. 1, 2023

Language: Английский

Citations

2
Letter: Low to moderate alcohol intake and progression of non‐alcoholic fatty liver disease DOI Open Access

Panyao Gu,

Yuanbin Liu, Shu‐Jun Wei

et al.

Alimentary Pharmacology & Therapeutics, Journal Year: 2023, Volume and Issue: 57(8), P. 924 - 925

Published: March 23, 2023

LINKED CONTENT This article is linked to Magherman et al paper. To view this article, visit https://doi.org/10.1111/apt.17388

Language: Английский

Citations

0
Current data regarding homeostasis of tissues oxygenation in pathophysiological and therapeutic circumstances DOI Creative Commons
Constantin Munteanu, Mihaela Antonina Călin, Dragoș Manea

et al.

Balneo and PRM Research Journal, Journal Year: 2023, Volume and Issue: 14(Vol.14, no.2), P. 565 - 565

Published: June 23, 2023

Oxygen is essential for cellular respiration and energy production. Tissue oxygenation refers to delivering oxygen cells throughout the body. Microcirculation brings blood through small sanguine vessels maintain cells' supply of nutrients oxygen. Optimal tissue microcirculation are maintaining healthy tissue. Conversely, poor can cause damage, impair wound healing, increase infection risk. Several factors affect microcirculation, including age, lifestyle (such as smoking stress), underlying medical conditions diabetes high pressure). To improve individuals engage in habits such regular exercise, eating, stress management, avoiding smoking. also be looked therapeutic, given that topical cosmetic treatments massage, pelotherapy, hydrotherapy, moisturizers, certain skin care products help pro-mote at somatic level. In scientific literature, focus on hypoxia rather than oxygenation. This article proposes a paradigm shift emphasizes homeostatic importance pathophysiological therapeutic circumstances. The systematic review data from last 2 years (2021-2022) meta-analysis performed will contribute practical approach pathology circumscribed Keywords: oxygenation; Hypoxia; Microcirculation; Homeostasis; Microenvironment

Language: Английский

Citations

0