Investigating Frailty, Polypharmacy, Malnutrition, Chronic Conditions, and Quality of Life in Older Adults: Large Population-Based Study (Preprint) DOI
Yunmei Liu, Lei Huang,

Fei Hu

et al.

Published: July 6, 2023

BACKGROUND Aging, a significant public health issue, is associated with multiple concurrent chronic diseases and aging-related conditions (geriatric syndromes). OBJECTIVE This study aims to investigate the impact of age on geriatric syndromes intercorrelations between quality life (QoL) in older adults (aged ≥65 years) at population level. METHODS A large representative sample was randomly selected from county China, Feidong, 17 towns 811,867 residents. Multiple conditions, (frailty, polypharmacy, malnutrition), QoL were assessed compared. Associations demographic information using multivariable-adjusted logistic regression. Intercorrelations age, syndromes, investigated both correlation analysis restricted cubic splines–based dose-response analysis. RESULTS Older comprised 43.42% (3668/8447) entire population. The prevalence frailty, premalnutrition or malnutrition, impaired (median 73, IQR 69-78 years; 1871/3668, 51% men) 8.26% (303/3668), 15.59% (572/3668), 3.22% (118/3668), 10.8% (396/3668), respectively. Different sex subgroups mostly had similar (except that frailty occurred more often age). Premalnutrition malnutrition lower frequency obesity higher constipation, polypharmacy diabetes constipation hernia, hypertension, diabetes, physical disability, constipation. Mini Nutritional Assessment–Short Form, Groningen Frailty Indicator, EQ-5D-5L scores, as well number medications used, predicted each other QoL. Impaired polypharmacy. At 1.5-year follow-up, linked baseline, baseline. Causal mediation analyses showed mediated link worse CONCLUSIONS In this population-based adults, ≥1 syndromes. Geriatric intercorrelated with, predictive of, QoL; causal relationships existed QoL, being mediators. findings might be biased by residual confounding factors. It important perform personalized syndrome assessments stratified condition; active prevention intervention for, any help reduce others improve

Language: Английский

One-Year Changes in Depressive Symptoms and Cognitive Function Among Brazilian Older Adults Attending Primary Care DOI Open Access

Fernanda Maria Silva Rivoli,

Antonio Pedro Gabriel Monteiro Galhardo,

Giancarlo Lucchetti

et al.

Healthcare, Journal Year: 2025, Volume and Issue: 13(7), P. 807 - 807

Published: April 3, 2025

Background: Aging is a global phenomenon closely associated with changes in cognitive function and mental health. These conditions substantially burden public health systems adversely affect the quality of life older adults. This study aimed to examine depressive symptoms over 12-month follow-up period cohort Brazilian adults attending primary care. Methods: observational longitudinal included randomized sample individuals aged ≥60 years residing São Paulo, Brazil, registered at Primary Healthcare Unit (PHU). Data collection involved administering sociodemographic questionnaire along two validated instruments: Geriatric Depression Scale-15 (GDS-15) Mini-Mental State Examination (MMSE). Linear regression models were used for analyses. Results: A total 368 included, 63% being men mean age 74.65 years. After one year, showed notable increase, GDS-15 score rising from 5.97 7.48 (Cohen-d = 0.542). Likewise, there was decrease MMSE ranging 19.11 18.88 0.216). Adjusted analyses revealed that baseline (B 0.696; p 0.048; R2 0.19) 0.444; < 0.001; 0.26) predictive their respective deteriorations period. Conclusions: Depressive decline place significant on aging societies. findings underscore importance continuous monitoring early intervention strategies mitigate impact enhance

Language: Английский

Citations

0
Frailty, polypharmacy, malnutrition, chronic conditions, and quality of life in the elderly: Large population-based study (Preprint) DOI Creative Commons
Yunmei Liu, Lei Huang,

Fei Hu

et al.

JMIR Public Health and Surveillance, Journal Year: 2024, Volume and Issue: 10, P. e50617 - e50617

Published: Aug. 15, 2024

Background Aging, a significant public health issue, is associated with multiple concurrent chronic diseases and aging-related conditions (geriatric syndromes). Objective This study aims to investigate the impact of age on geriatric syndromes intercorrelations between quality life (QoL) in older adults (aged ≥65 years) at population level. Methods A large representative sample was randomly selected from county China, Feidong, 17 towns 811,867 residents. Multiple conditions, (frailty, polypharmacy, malnutrition), QoL were assessed compared. Associations demographic information using multivariable-adjusted logistic regression. Intercorrelations age, syndromes, investigated both correlation analysis restricted cubic splines–based dose-response analysis. Results Older comprised 43.42% (3668/8447) entire population. The prevalence frailty, premalnutrition or malnutrition, impaired (median 73, IQR 69-78 years; 1871/3668, 51% men) 8.26% (303/3668), 15.59% (572/3668), 3.22% (118/3668), 10.8% (396/3668), respectively. Different sex subgroups mostly had similar (except that frailty occurred more often age). Premalnutrition malnutrition lower frequency obesity higher constipation, polypharmacy diabetes constipation hernia, hypertension, diabetes, physical disability, constipation. Mini Nutritional Assessment–Short Form, Groningen Frailty Indicator, EQ-5D-5L scores, as well number medications used, predicted each other QoL. Impaired polypharmacy. At 1.5-year follow-up, linked baseline, baseline. Causal mediation analyses showed mediated link worse Conclusions In this population-based adults, ≥1 syndromes. Geriatric intercorrelated with, predictive of, QoL; causal relationships existed QoL, being mediators. findings might be biased by residual confounding factors. It important perform personalized syndrome assessments stratified condition; active prevention intervention for, any help reduce others improve

Language: Английский

Citations

3
Obesity in European nursing homes participating in nutritionDay 2016–2021—Prevalence and resident characteristics DOI Creative Commons
I. Galicia Ernst,

Isabella Worf,

S. Tarantino

et al.

Clinical Obesity, Journal Year: 2024, Volume and Issue: 14(6)

Published: Aug. 4, 2024

The objective of this study is to assess obesity prevalence and characterize European nursing home (NH) residents with comprehensively. Cross-sectional nutritionDay data from 2016 2021. Descriptive characterization NH ≥65 years without obesity. Binomial logistic regression identify factors associated A total 11 327 (73.8% female, 86.4 ± 7.9 years, mean body mass index 25.3 5.4 kg/m

Language: Английский

Citations

1
Polifarmácia em indivíduos com doenças crônicas não transmissíveis: idade, sexo, frequência e agravos recorrentes DOI
Milena Nunes Alves de Sousa, Laura Mourão Aragão, Eduarda Feitosa Bezerra

et al.

Cuadernos de Educación y Desarrollo, Journal Year: 2024, Volume and Issue: 16(6), P. e4658 - e4658

Published: June 26, 2024

Introdução: A polifarmácia associa-se ao uso de cinco ou mais medicações diárias, enquanto o dez é considerado hiperpolifarmácia. Tal prática tem forte relação com desfechos negativos, como menor adesão tratamento e aumento da ocorrência reações adversas. Essa observada, sobretudo, em idosos doenças crônicas não transmissíveis (DCNT), que constituem conjunto enfermidades infecciosas períodos prolongados latência curso. situação, atrelada à polimorbidade típica dessa faixa etária, aumenta a necessidade do vários medicamentos forma simultânea. Objetivo: Avaliar pacientes transmissíveis. Método: Trata-se uma Revisão Integrativa Literatura, utilizando estratégia busca << Polypharmacy AND “Noncommunicable Diseases” >> quatro bases dados inclusão trabalhos no recorte tempo 2014-2024, inglês texto completo. Dos 139 artigos analisados, amostra final ficou constituída por doze pesquisas. Resultados: Observou-se as relacionadas quadro foram hipertensão arterial (91,7%) diabetes (91,7%). Além disso, perfil dos indivíduos predominantemente feminino (83,3%) idade acima igual 65 anos Em frequência polifarmácia, metade apresentou incidência inferior 50.0%, outra foi ≥ 50.0%. Conclusão: prevalente mulheres idosas (≥ anos) acometidas e/ou diabetes. No entanto, essencial dar visibilidade essa questão para garantir um melhor reconhecimento problemática meio científico.

Citations

0
ATENÇÃO FARMACÊUTICA NA POLIFARMÁCIA EM IDOSOS COM DOENÇAS METABÓLICAS: UMA REVISÃO INTEGRATIVA DA LITERATURA DOI Open Access

Izabela Sales Cazuza,

Thiago Serrão Pinto

Revista Foco, Journal Year: 2024, Volume and Issue: 17(11), P. e6704 - e6704

Published: Nov. 18, 2024

É evidente um aumento expressivo da população idosa em todo o mundo assim como as Doenças Crônicas Não Transmissíveis Hipertensão, diabetes, muito comum idosos. Acompanhado disso a necessidade de uso medicamentos diversos chamada polifarmácia. O objetivo deste estudo é sintetizar e analisar criticamente evidências disponíveis sobre atenção farmacêutica na polifarmácia idosos com doenças metabólicas, por meio análise abrangente literatura existente. Trata-se uma Revisão integrativa delineada seis importantes etapas. As bases dados selecionadas para este foram: Medline, Lilacs, Scielo Pubmed. Para elaboração do foram considerados artigos publicados linha temporal estabecido entre ano 2020 2024. Foi feito relação nos Descritores Ciências Saúde (DeCS) Medical Subject Headings (MeSH) seguido sprint busca obedecendo estratégia PICo. refinamento dos utilizou-se software Rayyan. Este seguiu rigorosamente os critérios inclusão estabelecidos. Foram incluidos sete (7) nesta pesquisa que abordaram temática. encontrado evidencias demanda idosos, principais achados patológicos, destaque hipertensão, diabete dislipidemia, além maior publico idoso feminino. Por fim, merece apresentar impacto saúde e, dessa forma, especializada atuação profissional farmacêutico.

Citations

0
Effects of yogic practices on polypharmacy DOI Open Access

Balaji Pa,

Smitha R Varne

Indian Journal of YOGA Exercise & Sport Science and Physical Education, Journal Year: 2023, Volume and Issue: unknown, P. 1 - 10

Published: Dec. 19, 2023

The occurrence and concurrency of Noncommunicable chronic diseases increase with age, therefore, the number medications used increases correspondingly. Polypharmacy is a scenario in which five or more are consumed concurrently (regardless dose duration consumption), leads to reduced quality life, physical problems, increased drug interactions, adverse effects, medical complications cost treatment. Moreover, polypharmacy incidence falls, frequency hospital admission, length stay, death rate among patients, especially elderly population. This would allow therapies like Yoga, pranayama, meditation act as an effective mainstay adjunctive alternative therapy for many disorders, it can be cost-effective, patient-compliant, clinically efficacious most negligible side effects. However, very few studies have focused on impact yogic practices reducing dosage patients. Hence, Medline English literature search was planned review all demonstrating dose-response effect between number/dosage medication reduction different disorders. Data extracted analyzed depicted that practice result not only but also dosages hypertension, type 2 diabetes mellitus, bronchial asthma, arthritis, sleep obsessive-compulsive disorder (OCD), gastrointestinal disorders constipation irritable bowel syndrome.

Language: Английский

Citations

0
Investigating Frailty, Polypharmacy, Malnutrition, Chronic Conditions, and Quality of Life in Older Adults: Large Population-Based Study (Preprint) DOI
Yunmei Liu, Lei Huang,

Fei Hu

et al.

Published: July 6, 2023

BACKGROUND Aging, a significant public health issue, is associated with multiple concurrent chronic diseases and aging-related conditions (geriatric syndromes). OBJECTIVE This study aims to investigate the impact of age on geriatric syndromes intercorrelations between quality life (QoL) in older adults (aged ≥65 years) at population level. METHODS A large representative sample was randomly selected from county China, Feidong, 17 towns 811,867 residents. Multiple conditions, (frailty, polypharmacy, malnutrition), QoL were assessed compared. Associations demographic information using multivariable-adjusted logistic regression. Intercorrelations age, syndromes, investigated both correlation analysis restricted cubic splines–based dose-response analysis. RESULTS Older comprised 43.42% (3668/8447) entire population. The prevalence frailty, premalnutrition or malnutrition, impaired (median 73, IQR 69-78 years; 1871/3668, 51% men) 8.26% (303/3668), 15.59% (572/3668), 3.22% (118/3668), 10.8% (396/3668), respectively. Different sex subgroups mostly had similar (except that frailty occurred more often age). Premalnutrition malnutrition lower frequency obesity higher constipation, polypharmacy diabetes constipation hernia, hypertension, diabetes, physical disability, constipation. Mini Nutritional Assessment–Short Form, Groningen Frailty Indicator, EQ-5D-5L scores, as well number medications used, predicted each other QoL. Impaired polypharmacy. At 1.5-year follow-up, linked baseline, baseline. Causal mediation analyses showed mediated link worse CONCLUSIONS In this population-based adults, ≥1 syndromes. Geriatric intercorrelated with, predictive of, QoL; causal relationships existed QoL, being mediators. findings might be biased by residual confounding factors. It important perform personalized syndrome assessments stratified condition; active prevention intervention for, any help reduce others improve

Language: Английский

Citations

0