Medicina, Journal Year: 2024, Volume and Issue: 60(11), P. 1745 - 1745
Published: Oct. 24, 2024
: The inappropriate use of antibiotics can lead to antimicrobial resistance. Overprescribing in dental practice has been reported. This study aimed describe patterns antibiotic prescription for treating and preventing odontogenic infections based on reports from Lithuanian dentists.
Language: Английский
Russian Chemical Reviews, Journal Year: 2024, Volume and Issue: 93(3), P. RCR5108 - RCR5108
Published: March 1, 2024
The existing additives for dental restorative materials used in therapeutic dentistry, dentures, orthodontic appliances and adhesives (for example, metal oxide nanoparticles) also to root canal irrigants endodontics mouthwashes can be toxic humans, cause allergic reactions accumulate organs tissues. Today, a relevant trend is development of that have an antimicrobial effect are non-toxic humans. A promising alternative the above-mentioned phyto-components, including plant propolis extracts, since they cheap non-toxic. This review devoted natural orthodontics, dentistry endodontics. makes recommendations regarding additional research required practical implementation considered (filling materials, mouthwashes, orthopaedic products), examines influence on physicochemical physicomechanical properties polymer outlines advantages disadvantages compared synthetic ones. main challenges this area narrow range microorganisms which was studied (which mainly <i>S. mutans, E. faecalis, C. albicans</i>) predominance <i>in vitro</i> studies over clinical studies. covers published data past five years.<br> bibliography includes 123 references.
Language: Английский
Citations
23
Antibiotics, Journal Year: 2024, Volume and Issue: 13(5), P. 460 - 460
Published: May 17, 2024
Background: Dentists bear the burden of responsibility for antimicrobial resistance since antibiotics are drugs most prescribed by dentists. Often, “inappropriate” antibiotic use is considered as a “gray area” dentists mainly due to ethical challenges associated with clinical judgement depending on patients and/or prescribers. Aim: The study aimed assess whether and in what way dental principles underpin rational investigating perceptions postgraduate undergraduate students without formal knowledge ethics. Method: A cross-sectional anonymous survey comprised nine close-ended questions was conducted among (n = 125). investigated practice appropriate prescribing relied respect three basic ethics: autonomy, non-maleficence, beneficence. Results: Results show that exhibit lack ethics results an inappropriate antibiotic-prescribing practice: when it not necessary, examination, or indications within competence dentist. Multivariate regression analysis revealed there significant difference between under- postgraduates. Conclusions: Within pharmacology course, review scenarios which cover both complexities regarding should be introduced educational approach.
Language: Английский
Citations
5
Antibiotics, Journal Year: 2024, Volume and Issue: 13(7), P. 645 - 645
Published: July 12, 2024
In response to the global trend of decreasing antibiotic usage, this study aimed evaluate nature and frequency prescriptions in conjunction with endodontic therapy Croatia assess attitudes Croatian dental practitioners towards treatment patients susceptible bacterial endocarditis. A survey questionnaire was sent all Croatia, achieving a rate 27%. The most frequently prescribed penicillin clavulanic acid (63.4%), while standalone less prevalent (18.6%). For exhibiting allergies, 90% respondents indicated clindamycin as their preferred alternative. Antibiotics were mostly for localized acute apical abscesses without fever, followed by prophylaxis infectious endocarditis cellulitis. Only 1.3% reported frequent accompanying local treatment. While substantial proportion surveyed professed familiarity latest guidelines prophylaxis, choice antibiotics did not consistently reflect claim. Most conducted procedures on at risk findings highlight need targeted continuing education Republic ensuring practices align current trends prescription.
Language: Английский
Citations
5
Journal of Conservative Dentistry and Endodontics, Journal Year: 2024, Volume and Issue: 27(5), P. 458 - 484
Published: May 1, 2024
Background and Objectives: The present systematic review aims to assess the success rate of pulp regeneration treatment, according American Association Endodontists (AAE) criteria, using different bioactive materials in permanent teeth pediatric subjects (6–17 years age). Materials Methods: study protocol was registered on PROSPERO adhered Preferred Reporting Items for Systematic Reviews Meta-analyses statement. question formulation accomplished PICO model, an electronic search carried out Scopus, MEDLINE/PubMed, Web Science, Cochrane databases till April 1, 2023. A total 30 studies were established fulfill inclusion criteria this review. Results: 273 have been treated with treatment. By comparing biomaterials defined by AAE, material associated a higher found be white mineral trioxide aggregate. However, overall treatment reported 248 (91.20%). Conclusions: Data obtained support potential that regenerative endodontics aids continuing root development immature teeth. Further are needed more extensive evaluation use endodontics.
Language: Английский
Citations
4
Journal of Clinical Medicine, Journal Year: 2024, Volume and Issue: 13(18), P. 5402 - 5402
Published: Sept. 12, 2024
This study addresses the limited body of literature concerning impact photobiomodulation on complications following mandibular third molar extractions.
Language: Английский
Citations
4
Materials, Journal Year: 2025, Volume and Issue: 18(3), P. 570 - 570
Published: Jan. 27, 2025
Autologous blood centrifugation produces various forms of platelet concentrates widely used in tissue regenerative therapies due to their high concentrations growth factors and abundance autologous cells. Advanced Platelet-Rich Fibrin (A-PRF), introduced as a low-speed product, contains an even higher concentration factors, greater number cells, looser fibrin clot structure compared previous Leukocyte (L-PRF). This study aims assess the potential A-PRF local delivery system for antibiotics. Different (0.5 mg/mL, 0.25 0.125 mg/mL) injectable amoxicillin (AMX) metronidazole (MTZ) were preliminarily tested impact on formation, with 0.5 mg/mL selected subsequent experiments. Blood samples from healthy volunteers supplemented antibiotics centrifuged form clots. Antibiotic-enriched clots immersed phosphate-buffered saline (1x PBS) analyzed at 24 h, 72 7 days, 14 days. AMX showed consistent release (mean: 19.9 ± 4.8 ng/mL h) over while MTZ demonstrated variability 12.8 4.5 h). remained constant 14-day period, no significant variations among patients. In contrast, displayed progressively lower time. Microbiological analysis revealed bacterial inhibition zones Fusobacterium nucleatum (AMX: 23 mm, MTZ: 28 mm) Prevotella intermedia 34 30 h. These findings suggest that can act effective antibiotic system, maintaining sustained antimicrobial activity potentially reducing need systemic
Language: Английский
Citations
0
The Journal of the American Dental Association, Journal Year: 2025, Volume and Issue: unknown
Published: March 1, 2025
Language: Английский
Citations
0
European Journal Of Dental Education, Journal Year: 2025, Volume and Issue: unknown
Published: April 2, 2025
Several studies highlighted a lack of knowledge dentists concerning antibiotic stewardship. The objectives this study were to evaluate dental students' level in infectiology and stewardship, identify factors associated with high knowledge. A cross-sectional national multicentre survey was conducted 2022-2023 through self-administered internet-based questionnaire. score (out 34) calculated for each included student based on their questionnaire results. Hierarchical clustering methods used clusters students according score. This approach distinct levels. logistic regression model then applied associate specific these association between the cluster highest characteristics faculties assessed using regressions. total 415 included. Two identified: 'average knowledge' 290 (70%) (median score: 26/34, IQR: 24; 27), while 'high grouped 125 (30%) 30/34, 29; 32). Mandatory courses multiple learning modalities higher French seem have as evidenced by median cluster, which are objectively compared maximum 34. We identified several that might help conceive standardised recommendations.
Language: Английский
Citations
0
Antibiotics, Journal Year: 2024, Volume and Issue: 13(9), P. 876 - 876
Published: Sept. 12, 2024
Antibiotics are used in endodontic treatment to control acute odontogenic infection and for prophylactic purposes. This study aimed investigate the knowledge of dentists from Federation Bosnia Herzegovina about choice routes antibiotic administration endodontics.
Language: Английский
Citations
2
Antibiotics, Journal Year: 2024, Volume and Issue: 13(9), P. 899 - 899
Published: Sept. 20, 2024
Background: Streptococcus mutans is a leading causative agent of dental caries and exerts pathogenicity by forming biofilms. Dental continues to be significant public health issue worldwide, affecting an estimated 2.5 billion people, showing 14.6% increase over the past decade. Herein, antibacterial potential Chlorophyllin extracted from Spinacia oleracea was evaluated against biofilm-forming S. via in vitro silico studies. Methodology: The antimicrobial activity chlorophyllin extract isolates tested using agar well diffusion method. also mutans. docked with antigen I/II (AgI/II) protein evaluate its mechanism. chemical structure canonical SMILES format were obtained PubChem. Additionally, adsorption, distribution, metabolism, excretion, toxicity (ADMET) analyses performed ADMETlab 2.0 assess pharmacokinetic properties. Results: An assay revealed that all susceptible showed variety inhibition zones ranging 32 41 mm. reduces biofilm strength four strong moderate six weak. antibiofilm measured reduction number functional groups observed Fourier Transform Infrared Spectrometer (FTIR) spectra extracellular polymeric substance (EPS) samples. binding AgI/II proteins mutans, which are involved adherence tooth surface initiating formation. ADMET analysis safety exhibited favorable Conclusions: stands out as promising profile highlights suitability for further investigation therapeutic agent.
Language: Английский
Citations
2