Bio-Based Electrospun Fibers for Wound Healing

Journal of Functional Biomaterials, Journal Year: 2020, Volume and Issue: 11(3), P. 67 - 67

Published: Sept. 22, 2020

Being designated to protect other tissues, skin is the first and largest human body organ be injured for this reason, it accredited with a high capacity self-repairing. However, in case of profound lesions or large surface loss, natural wound healing process may ineffective insufficient, leading detrimental painful conditions that require repair adjuvants tissue substitutes. In addition conventional care options, biodegradable polymers, both synthetic biologic origin, are gaining increased importance their biocompatibility, biodegradation, bioactive properties, such as antimicrobial, immunomodulatory, cell proliferative, angiogenic. To create microenvironment suitable process, key property ability polymer spun into submicrometric fibers (e.g., via electrospinning), since they mimic fibrous extracellular matrix can support neo- growth. A number polymers used biomedical sector comply definition bio-based (known also biopolymers), which recently being industrial sectors reducing material energy impact on environment, derived from renewable biological resources. review, after description fundamental concepts healing, emphasis advanced dressings, recent developments electrospun structures efficient applications highlighted discussed. This review aims improve awareness use medical devices.

Language: Английский

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Material Function of Mycelium-Based Bio-Composite: A Review

Frontiers in Materials, Journal Year: 2021, Volume and Issue: 8

Published: Sept. 30, 2021

Mycelium-based bio-composite materials have been invented and widely applied to different areas, including construction, manufacturing, agriculture, biomedical. As the vegetative part of a fungus, mycelium has unique capability utilize agricultural crop waste (e.g., sugarcane bagasse, rice husks, cotton stalks, straw, stover) as substrates for growth its network, which integrates wastes from pieces continuous composites without energy input or generating extra waste. Their low-cost environmentally friendly features attract interest in their research commercialization. For example, mycelium-based foam sandwich actively developed construction structures. It can be used synthetic planar plastic films sheets), larger low-density objects foams plastics), semi-structural paneling, flooring, furniture, decking). is shown that material function these further tuned by controlling species growing conditions, post-growth processing method meet specific mechanical requirement applications structural support, acoustic thermal insulation). Moreover, produce chitin chitosan, clinical trials wound healing, showing potential biomedical applications. Given strong multiple advantages such material, we are interested studying it in-depth reviewing current progress related study this review paper.

Language: Английский

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Lignins as Promising Renewable Biopolymers and Bioactive Compounds for High-Performance Materials

Polymers, Journal Year: 2023, Volume and Issue: 15(15), P. 3177 - 3177

Published: July 26, 2023

The recycling of biomass into high-value-added materials requires important developments in research and technology to create a sustainable circular economy. Lignin, as component biomass, is multipurpose aromatic polymer with significant potential be used renewable bioresource many fields which it acts both promising biopolymer bioactive compound. This comprehensive review gives brief insights the recent technological trends on lignin development utilization. It divided ten main sections, starting an outlook its diversity; properties possibilities raw material for fuels, chemicals, plastics, or thermoset substitutes; new use compound nanoparticles, hydrogels, 3D-printing-based biomaterials, energy production storage. In each section are presented preparation lignin-based especially green approaches obtaining multifunctional blends bio(nano)composites; most suitable type category envisaged products; obtained materials, etc. Different application categories within various sectors, could provide completely conversion, such agriculture environment protection, food packaging, biomedicine, cosmetics, also described. medical therapeutic lignin-derived evidenced applications antimicrobial, antiviral, antitumor agents; carriers drug delivery systems controlled/targeting release; tissue engineering wound healing; coatings, natural sunscreen, surfactants. Lignin mainly fuel, and, recently, studies highlighted more bioenergy technologies, supercapacitor electrode, photocatalysts, photovoltaics.

Language: Английский

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Pullulan in pharmaceutical and cosmeceutical formulations: A review

International Journal of Biological Macromolecules, Journal Year: 2023, Volume and Issue: 231, P. 123353 - 123353

Published: Jan. 18, 2023

Language: Английский

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Nanotheranostics to target antibiotic-resistant bacteria: Strategies and applications

OpenNano, Journal Year: 2023, Volume and Issue: 11, P. 100138 - 100138

Published: March 5, 2023

Various health agencies, such as the European Medical Agency (EMA), Centers for Disease Control and Prevention (CDC), World Health Organization (WHO), timely cited upsurge of antibiotic resistance a severe threat to public global economy. Importantly, there is rise in nosocomial infections among covid-19 patients in-hospitalized with delineating disorder. Most are related bacteria residing biofilm, which commonly formed on material surfaces. In biofilms, microcolonies various live syntropy; therefore, their require higher dosage or cocktail broad-spectrum antibiotics, aggravating severity resistance. Notably, lack intrinsic antibacterial properties commercial-grade materials desires develop newer functionalized prevent biofilm formation To devise strategies, prepared at nanoscale demonstrated reasonable enhanced activity antimicrobial agents (that encapsulated/chemically onto surface). this manuscript, we compiled nanosized materials, specifying role targeting specific strains bacteria. We also enlisted examples nanomaterials, nanodevice, nanomachines, nano-camouflaging, nano-antibiotics bactericidal possible clinical implications.

Language: Английский

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Nanomaterials for Skin Delivery of Cosmeceuticals and Pharmaceuticals

Applied Sciences, Journal Year: 2020, Volume and Issue: 10(5), P. 1594 - 1594

Published: Feb. 27, 2020

Skin aging is described as dermatologic changes either naturally occurring over the course of years or result exposure to environmental factors (e.g., chemical products, pollution, infrared and ultraviolet radiations). The production collagen elastin, main structural proteins responsible for skin strength elasticity, reduced during aging, while their role in rejuvenation can trigger a wrinkle reversing effect. Elasticity loss, wrinkles, dry skin, thinning are some signs that be associated with aging. To overcome many strategies using natural synthetic ingredients being developed aiming reduce and/or treat age-related problems spots, hyper- hypopigmentation). Among different approaches tissue regeneration, use nanomaterials loaded cosmeceuticals phytochemicals, vitamins, hyaluronic acid, growth factors) has become an interesting alternative. Based on bioactivities nanoformulations efficient delivery systems, several cosmeceutical pharmaceutical products now available market mitigate aged skin. This manuscript discusses state art commonly used topical administration active formulated nanopharmaceuticals nanocosmeceuticals anti-aging.

Language: Английский

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Chitin and Chitosan Derivatives as Biomaterial Resources for Biological and Biomedical Applications

Molecules, Journal Year: 2020, Volume and Issue: 25(24), P. 5961 - 5961

Published: Dec. 16, 2020

Chitin is a long-chain polymer of N-acetyl-glucosamine, which regularly found in the exoskeleton arthropods including insects, shellfish and cell wall fungi. It has been known that chitin can be used for biological biomedical applications, especially as biomaterial tissue repairing, encapsulating drug delivery. However, postulated an inducer proinflammatory cytokines certain diseases asthma. Likewise, chitosan, N-acetyl-glucosamine d-glucosamine derived from deacetylation, chitosan oligosaccharide, short chain polymer, have their potential therapeutic effects, anti-inflammatory, antioxidant, antidiarrheal, anti-Alzheimer effects. This review summarizes utilization limitation chitin, oligosaccharide variety diseases. Furthermore, future direction research development applications discussed.

Language: Английский

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Pullulan for Advanced Sustainable Body- and Skin-Contact Applications

Journal of Functional Biomaterials, Journal Year: 2020, Volume and Issue: 11(1), P. 20 - 20

Published: March 18, 2020

The present review had the aim of describing methodologies synthesis and properties biobased pullulan, a microbial polysaccharide investigated in last decade because its interesting potentialities several applications. After implications pullulan nano-technology, biodegradation, compatibility with body skin, sustainability, current applications are described, assessing this biopolymer biomedical, personal care, cosmetic sector, especially contact skin.

Language: Английский

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Insect Chitin-Based Nanomaterials for Innovative Cosmetics and Cosmeceuticals

Cosmetics, Journal Year: 2021, Volume and Issue: 8(2), P. 40 - 40

Published: May 24, 2021

Chitin and its derivatives are attracting great interest in cosmetic cosmeceutical fields, thanks to their antioxidant antimicrobial properties, as well biocompatibility biodegradability. The classical source of chitin, crustacean waste, is no longer sustainable fungi, a possible alternative, have not been exploited at an industrial scale yet. On the contrary, breeding bioconverting insects, especially Diptera Hermetia illucens, becoming increasingly popular worldwide. Therefore, exoskeletons, consisting chitin major component, represent waste stream facilities that could be for many applications. Insect indeed, suggests application same fields biopolymer, because comparable commercial characteristics. This review reports several applications based on derivatives. In this context, nanofibers nanofibrils, produced from proved excellent active compounds carriers ingredients personal care. Consequently, insect-based complexes with hyaluronic acid lignin, other chitin-derived compounds, may considered new appropriate potential polymer used fields.

Language: Английский

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Valorization of Marine Waste: Use of Industrial By-Products and Beach Wrack Towards the Production of High Added-Value Products

Frontiers in Marine Science, Journal Year: 2021, Volume and Issue: 8

Published: Oct. 20, 2021

Biomass is defined as organic matter from living organisms represented in all kingdoms. It recognized to be an excellent source of proteins, polysaccharides and lipids and, such, embodies a tailored feedstock for new products processes apply green industries. The industrial focused on the valorization terrestrial biomass are well established, but marine sources still represent untapped resource. Oceans seas occupy over 70% Earth’s surface used intensively worldwide economies through fishery industry, logistical routes, mining ores exploitation fossil fuels, among others. All these activities produce waste. other unused derives beach wrack or washed-ashore material, especially highly eutrophicated ecosystems. development high-added-value side streams has been given priority recent years due detection broad range biopolymers, multiple nutrients functional compounds that could find applications human consumption use livestock/pet food, pharmaceutical This review comprises thematic approach waste valorization, addressing main achievements biotechnology advancing circular economy, ranging bioremediation pollution treatment energy biomedical applications. also includes overview three selected case study areas: Norway, Scotland, Baltic Sea.

Language: Английский

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