Omega-3
polyunsaturated
fatty
acids
(ɷ-3
PUFAs)
offer
diverse
health
benefits,
such
as
supporting
cardiovascular
health,
improving
cognitive
function,
promoting
joint
and
musculoskeletal
contributing
to
healthy
aging.
Despite
their
advantages,
challenges
like
oxidation
susceptibility,
low
bioavailability,
potential
adverse
effects
at
high
doses
persist.
Nanoparticle
encapsulation
emerges
a
promising
avenue
address
these
limitations
while
preserving
stability,
enhanced
controlled
release.
This
comprehensive
review
explores
the
therapeutic
roles
of
omega-3
acids,
critically
appraising
shortcomings
delving
into
modern
strategies.
Furthermore,
it
advantages
Metal-organic
framework
nanoparticles
(MOF
NPs)
compared
other
commonly
utilized
in
effectiveness
within
drug
delivery
systems
(DDS).
Additionally,
outlines
future
research
directions
fully
exploit
benefits
encapsulated
formulations
for
disease
treatment.
Advances in Colloid and Interface Science,
Journal Year:
2024,
Volume and Issue:
332, P. 103263 - 103263
Published: July 31, 2024
The
growing
field
of
nanotechnology
has
witnessed
numerous
advancements
over
the
past
few
years,
particularly
in
development
engineered
nanoparticles.
Compared
with
bulk
materials,
metal
nanoparticles
possess
more
favorable
properties,
such
as
increased
chemical
activity
and
toxicity,
owing
to
their
smaller
size
larger
surface
area.
Metal
exhibit
exceptional
stability,
specificity,
sensitivity,
effectiveness,
making
them
highly
useful
biomedical
field.
are
high
demand
nanotechnology,
including
Au,
Ag,
Pt,
Cu,
Zn,
Co,
Gd,
Eu,
Er.
These
particles
excellent
physicochemical
amenable
functionalization,
non-corrosiveness,
varying
optical
electronic
properties
based
on
shape.
can
be
modified
different
targeting
agents
antibodies,
liposomes,
transferrin,
folic
acid,
carbohydrates.
Thus,
hold
great
promise
for
various
applications
photoacoustic
imaging,
magnetic
resonance
computed
tomography
(CT),
photothermal,
photodynamic
therapy
(PDT).
Despite
potential,
safety
considerations,
regulatory
hurdles
must
addressed
safe
clinical
applications.
This
review
highlights
nanoparticle
engineering
explores
integration
emerging
technologies
bioimaging,
cancer
therapeutics
nanomedicine.
By
offering
valuable
insights,
this
comprehensive
offers
a
deep
understanding
potential
research.
Molecules,
Journal Year:
2024,
Volume and Issue:
29(11), P. 2534 - 2534
Published: May 28, 2024
The
symbiotic
relationship
between
nitrogen-fixing
cyanobacteria
and
plants
offers
a
promising
avenue
for
sustainable
agricultural
practices
environmental
remediation.
This
review
paper
explores
the
molecular
interactions
nanoparticles,
shedding
light
on
their
potential
synergies
in
nanotechnology.
Delving
into
evolutionary
history
specialized
adaptations
of
cyanobacteria,
this
highlights
pivotal
role
fixing
atmospheric
nitrogen,
which
is
crucial
ecosystem
productivity.
discusses
unique
characteristics
metal
nanoparticles
emerging
applications
agriculture,
including
improved
nutrient
delivery,
stress
tolerance,
disease
resistance.
It
delves
complex
mechanisms
nanoparticle
entry
plant
cells,
intracellular
transport,
localization,
uncovering
impact
root-shoot
translocation
systemic
distribution.
Furthermore,
elucidates
cellular
responses
to
exposure,
emphasizing
oxidative
stress,
signaling
pathways,
enhanced
uptake.
as
carriers
essential
nutrients
implications
nutrient-use
efficiency
crop
yield
are
also
explored.
Insights
modulation
responses,
resistance,
phytoremediation
strategies
demonstrate
multifaceted
benefits
agriculture.
Current
trends,
prospects,
challenges
nanotechnology
discussed,
underscoring
need
responsible
safe
utilization.
By
harnessing
power
leveraging
attributes
paves
way
innovative,
sustainable,
efficient
practices.
Journal of Nanobiotechnology,
Journal Year:
2024,
Volume and Issue:
22(1)
Published: May 15, 2024
With
increasing
proportion
of
the
elderly
in
population,
age-related
diseases
(ARD)
lead
to
a
considerable
healthcare
burden
society.
Prevention
and
treatment
ARD
can
decrease
negative
impact
aging
disease.
The
rate
is
closely
associated
with
production
high
levels
reactive
oxygen
species
(ROS).
ROS-mediated
oxidative
stress
triggers
aging-related
changes
through
lipid
peroxidation,
protein
oxidation,
DNA
oxidation.
Antioxidants
control
autoxidation
by
scavenging
free
radicals
or
inhibiting
their
formation,
thereby
reducing
stress.
Benefiting
from
significant
advances
nanotechnology,
large
number
nanomaterials
ROS-scavenging
capabilities
have
been
developed.
be
divided
into
two
categories:
as
carriers
for
delivering
drugs,
themselves
activity.
This
study
summarizes
current
prevention
ARD,
highlights
potential
mechanisms
used
discusses
challenges
prospects
applications.
Frontiers in Cellular and Infection Microbiology,
Journal Year:
2022,
Volume and Issue:
12
Published: June 21, 2022
The
biofilm
community
of
microorganisms
has
been
identified
as
the
dominant
mode
microbial
growth
in
nature
and
a
common
characteristic
different
such
Pseudomonas
aeruginosa,
Staphylococcus
aureus,
epidermidis.
structure
helps
protection
from
environmental
threats
including
host
immune
system
antimicrobial
agents.
Thus,
led
to
higher
prevalence
multidrug-resistant
(MDR)
strains
recent
years.
In
this
regard,
use
new
class
antibiotics,
natural
compounds,
anti-biofilm
enzymes
considered
for
destruction
biofilm.
However,
drawbacks
low
penetration,
high
susceptibility
degradation,
instability,
poor
solubility
aqueous
solutions
limit
agents
(ABAs)
clinical
setting.
As
such,
studies
have
using
poly
lactic-
co
-glycolic
acid
(PLGA)-based
nanoplatforms
(PLGA
NPFs)
delivery
ABAs
that
reported
promising
results.
These
particles,
due
proper
drug
loading
release
kinetics,
could
suppress
attachment,
colonization,
formation
long
time.
Additionally,
PLGA
NPFs,
because
drug-loading
efficiencies,
hydrophilic
surface,
negative
charge,
electrostatic
interaction,
lead
effective
penetration
antibiotics
deeper
layer
biofilm,
thereby
eliminating
NPFs
be
potential
candidate
coating
catheters
other
medical
material
surfaces
inhibition
exact
interaction
should
evaluated
animal
studies.
future
goal
will
develop
formulations
systems
can
used
treatment
MDR
since
interactions
these
structures
are
not
elucidated.
present
review
article,
we
discussed
various
aspects
usage
along
with
methods
procedures
improving
NPF
efficacy
against
Advanced Functional Materials,
Journal Year:
2023,
Volume and Issue:
33(26)
Published: March 31, 2023
Abstract
Cardiovascular
disease
(CVD)
is
the
number
one
cause
of
death
worldwide,
which
propels
development
advanced
technologies
for
CVD
diagnosis
and
treatment.
Biomarker‐responsive
nanomaterials
are
appealing
therapeutic
platforms
that
provide
new
horizons
theranostics.
In
this
review,
recent
advances
in
with
endogenous
biomarkers
as
stimuli
or
targets
theranostics
presented.
First,
categories
involved
comprehensively
itemized
based
on
pathological
mechanisms
including
pH,
reactive
oxygen
species,
lipids,
enzymes,
macrophage
receptors,
subendothelium
components,
platelet
inflammation,
osteopontin.
The
role
these
bridge‐building
between
then
Next,
biomedical
applications
responsive
to
treatment
elaborated.
Finally,
challenges
future
research
directions
biomarker‐responsive
also
discussed.
This
review
will
scientific
guidance
facilitate
clinical
nanomaterials.
Polymers,
Journal Year:
2023,
Volume and Issue:
15(5), P. 1177 - 1177
Published: Feb. 26, 2023
Cardiovascular
diseases
are
one
of
the
leading
global
causes
morbidity
and
mortality,
posing
considerable
health
economic
burden
on
patients
medical
systems
worldwide.
This
phenomenon
is
attributed
to
two
main
motives:
poor
regeneration
capacity
adult
cardiac
tissues
insufficient
therapeutic
options.
Thus,
context
calls
for
upgrading
treatments
deliver
better
outcomes.
In
this
respect,
recent
research
has
approached
topic
from
an
interdisciplinary
perspective.
Combining
advances
encountered
in
chemistry,
biology,
material
science,
medicine,
nanotechnology,
performant
biomaterial-based
structures
have
been
created
carry
different
cells
bioactive
molecules
repairing
restoring
heart
tissues.
regard,
paper
aims
present
advantages
approaches
tissue
engineering
regeneration,
focusing
four
strategies:
patches,
injectable
hydrogels,
extracellular
vesicles,
scaffolds
reviewing
most
developments
these
fields.
Chinese Medicine,
Journal Year:
2024,
Volume and Issue:
19(1)
Published: July 2, 2024
Abstract
Cardiovascular
disease
(CVD)
remains
the
predominant
cause
of
mortality
and
disability
worldwide.
Against
this
backdrop,
finding
effective
drugs
for
pharmacological
treatment
CVD
has
become
one
most
urgent
challenging
issues
in
medical
research.
Garlic
(
Allium
sativum
L.)
is
oldest
plants
world-renowned
its
dietary
medicinal
values.
Allicin
diallyl
thiosulfinate
)
primary
natural
active
ingredients
garlic,
which
been
proven
to
have
powerful
cardioprotective
effects
mediate
various
pathological
processes
related
CVD,
such
as
inflammatory
factor
secretion,
myocardial
cell
apoptosis,
oxidative
stress,
more.
Therefore,
allicin
holds
a
promising
application
prospect
CVD.
This
review
summarized
biological
functions
potential
mechanisms
including
antioxidation,
anti-inflammation,
anti-apoptosis
effects.
Reckoning
with
these,
we
delved
into
recent
studies
on
allicin’s
concerning
CVDs,
atherosclerosis,
hypertension,
infarction,
arrhythmia,
cardiac
hypertrophy,
heart
failure,
cardiotoxicity.
Further,
considering
tremendous
advancement
nanomedicine,
nanotechnology-based
drug
delivery
systems
show
promise
addressing
limitations
clinical
applications,
improving
solubility,
stability,
bioavailability.
Through
review,
hope
provide
reference
further
research
cardioprotection
development.
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