BioNanoScience, Journal Year: 2025, Volume and Issue: 15(2)
Published: March 19, 2025
Language: Английский
BioNanoScience, Journal Year: 2025, Volume and Issue: 15(2)
Published: March 19, 2025
Language: Английский
Journal of Water Process Engineering, Journal Year: 2023, Volume and Issue: 54, P. 103980 - 103980
Published: July 1, 2023
Language: Английский
Citations
70Pharmaceutics, Journal Year: 2024, Volume and Issue: 16(3), P. 370 - 370
Published: March 6, 2024
Alginate is a natural biopolymer widely studied for pharmaceutical applications due to its biocompatibility, low toxicity, and mild gelation abilities. This review summarizes recent advances in alginate-based encapsulation systems targeted drug delivery. formulations like microparticles, nanoparticles, microgels, composites fabricated by methods including ionic gelation, emulsification, spray drying, freeze drying enable tailored loading, enhanced stability, sustained release kinetics. microspheres prepared or provide gastric protection colon-targeted of orally delivered drugs. nanoparticles exhibit cellular uptake tumor-targeting capabilities through the permeation retention effect. Crosslinked alginate microgels allow high loading controlled profiles. Composite gels with cellulose, chitosan, inorganic nanomaterials display improved mechanical properties, mucoadhesion, tunable Alginate-based wound dressings containing antimicrobial promote healing burns chronic wounds topical Although well-established as excipient, more extensive vivo testing needed assess clinical safety efficacy emerging prior human trials. Future opportunities include engineered combining stimuli-responsiveness, active targeting, diagnostic capabilities. In summary, this discusses techniques oral, transdermal, intravenous delivery, an emphasis on approaches enabling therapeutic outcomes.
Language: Английский
Citations
30International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 259, P. 129129 - 129129
Published: Jan. 3, 2024
Language: Английский
Citations
27International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 263, P. 130296 - 130296
Published: Feb. 19, 2024
Language: Английский
Citations
25Waste and Biomass Valorization, Journal Year: 2024, Volume and Issue: 15(10), P. 5607 - 5637
Published: March 12, 2024
Language: Английский
Citations
17Biomaterials, Journal Year: 2025, Volume and Issue: unknown, P. 123134 - 123134
Published: Jan. 1, 2025
Language: Английский
Citations
4Carbohydrate Polymers, Journal Year: 2025, Volume and Issue: unknown, P. 123563 - 123563
Published: March 1, 2025
Language: Английский
Citations
2Materials Today Communications, Journal Year: 2022, Volume and Issue: 33, P. 104813 - 104813
Published: Oct. 31, 2022
Language: Английский
Citations
69Chemosphere, Journal Year: 2022, Volume and Issue: 307, P. 136008 - 136008
Published: Aug. 16, 2022
Language: Английский
Citations
48Gels, Journal Year: 2023, Volume and Issue: 9(5), P. 430 - 430
Published: May 22, 2023
Alginates are polysaccharides that produced naturally and can be isolated from brown sea algae bacteria. Sodium alginate (SA) is utilized extensively in the field of biological soft tissue repair regeneration owing to its low cost, high compatibility, quick moderate crosslinking. In addition their printability, SA hydrogels have found growing popularity engineering, particularly due advent 3D bioprinting. There a developing curiosity engineering with SA-based composite potential for further improvement terms material modification, molding process, application. This has resulted numerous productive outcomes. The use scaffolds cells tissues cell culture an innovative technique vitro models mimic vivo environment. Especially compared models, were more ethical cost-effective, they stimulate growth. article discusses sodium focusing on modification techniques providing comparative examination properties several hydrogels. review also covers hydrogel preparation techniques, catalogue patents covering different formulations discussed. Finally, applications future research areas concerning examined.
Language: Английский
Citations
38