Recent Developments in Monitoring of Organophosphorus Pesticides in Food Samples

Journal of Agriculture and Food Research, Journal Year: 2025, Volume and Issue: 19, P. 101709 - 101709

Published: Feb. 7, 2025

Language: Английский

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Multiple neurological effects associated with exposure to organophosphorus pesticides in man

Toxicology, Journal Year: 2022, Volume and Issue: 484, P. 153407 - 153407

Published: Dec. 18, 2022

Language: Английский

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Organophosphate-Pesticide-Mediated Immune Response Modulation in Invertebrates and Vertebrates

International Journal of Molecular Sciences, Journal Year: 2023, Volume and Issue: 24(6), P. 5360 - 5360

Published: March 10, 2023

Organophosphate pesticides (OPs) have greatly facilitated food production worldwide, and their use is not limited to agriculture the control of pests disease vectors. However, these substances can directly affect immune response non-target organisms. In this sense, exposure OPs negative effects on innate adaptive immunity, promoting deregulation in humoral cellular processes such as phagocytosis, cytokine expression, antibody production, cell proliferation, differentiation, which are crucial mechanisms for host defense against external agents. This review focuses scientific evidence toxic system organisms (invertebrates vertebrates) from a descriptive perspective immuno-toxic associated with susceptibility development bacterial, viral, fungal infectious diseases. During exhaustive review, we found that there an important gap study organisms, examples echinoderms chondrichthyans. It therefore increase number studies other species or indirectly affected by Ops, assess degree impact at individual level how affects higher levels, populations ecosystems.

Language: Английский

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Spent coffee grounds-derived carbon material as an effective adsorbent for removing multiple contaminants from wastewater: A comprehensive kinetic, isotherm, and thermodynamic study

Journal of Water Process Engineering, Journal Year: 2024, Volume and Issue: 63, P. 105507 - 105507

Published: May 17, 2024

Language: Английский

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In Silico Prediction of Chemical Acute Dermal Toxicity Using Explainable Machine Learning Methods

Chemical Research in Toxicology, Journal Year: 2024, Volume and Issue: 37(3), P. 513 - 524

Published: Feb. 21, 2024

The research on acute dermal toxicity has consistently been a crucial component in assessing the potential risks of human exposure to active ingredients pesticides and related plant protection products. However, it is difficult directly identify compounds through animal experiments alone. In our study, we separately integrated 1735 experimental data based rabbits 1679 rats construct prediction models using machine learning deep algorithms. best for two species achieved AUC values 78.0 82.0%, respectively, 10-fold cross-validation. Additionally, employed SARpy extract structural alerts, conjunction with Shapley additive explanation attentive FP heatmap, identified important features fragments associated toxicity. This approach offers valuable insights detection positive compounds. Moreover, standalone software tool was developed make easier. summary, would provide an effective evaluation pesticides, cosmetics, drug safety assessment.

Language: Английский

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The looming threat of profenofos organophosphate and microbes in action for their sustainable degradation

Environmental Science and Pollution Research, Journal Year: 2024, Volume and Issue: 31(10), P. 14367 - 14387

Published: Jan. 30, 2024

Language: Английский

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From Cell to Organ: Exploring the Toxicological Correlation of Organophosphorus Compounds in Living System

Toxicology, Journal Year: 2025, Volume and Issue: unknown, P. 154049 - 154049

Published: Jan. 1, 2025

Language: Английский

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EAACI Guidelines on Environmental Science for Allergy and Asthma—Recommendations on the Impact of Indoor Air Pollutants on the Risk of New‐Onset Asthma and on Asthma‐Related Outcomes

Allergy, Journal Year: 2025, Volume and Issue: 80(3), P. 651 - 676

Published: Feb. 28, 2025

ABSTRACT The EAACI Guidelines used the GRADE approach to evaluate impact of major indoor air pollutants (dampness and mould, cleaning agents, volatile organic compounds pesticides) on risk new‐onset asthma asthma‐related outcomes. guideline also acknowledges synergies among other components exposome (allergens, viruses, endotoxins). Very low certainty evidence was found for association between exposure increased worsening. Only mould there moderate asthma. Due quality evidence, conditional recommendations were formulated all pollutants. Recommendations are provided prevention, patient care mitigation in a framework supporting rational decisions healthcare professionals patients individualize improve management. For policymakers regulators this evidence‐informed supports setting legally binding standards goals at international, national local levels. Asthma management counselled by current guidelines can outcomes but community governmental measures improved needed achieve significant impact.

Language: Английский

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Pesticide Pollution: Detrimental Outcomes and Possible Mechanisms of Fish Exposure to Common Organophosphates and Triazines

Journal of Xenobiotics, Journal Year: 2022, Volume and Issue: 12(3), P. 236 - 265

Published: Sept. 2, 2022

Pesticides are well known for their high levels of persistence and ubiquity in the environment, because capacity to bioaccumulate disrupt food chain, they pose a risk animals humans. With focus on organophosphate triazine pesticides, present review aims describe current state knowledge regarding spatial distribution, bioaccumulation, mode action frequently used pesticides. We discuss processes by which pesticides active residues accumulated bioconcentrated fish, as toxic mechanisms involved, including biological redox activity, immunotoxicity, neuroendocrine disorders, cytotoxicity, is manifested oxidative stress, lysosomal mitochondrial damage, inflammation, apoptosis/autophagy. also explore potential research strategies close gaps our understanding toxicity environmental assessment

Language: Английский

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Deep eutectic solvents incorporated in a polymeric film for organophosphorus pesticide microextraction from water samples

Analytica Chimica Acta, Journal Year: 2024, Volume and Issue: 1318, P. 342940 - 342940

Published: July 2, 2024

Organophosphorus pesticides (OPPs) were extensively used in agriculture. Due to their adverse effect, there is a need for sensitive and reliable methods determine these agrochemicals. Microextraction techniques (ME) afford the opportunity substantially reduce amount of organic solvent classical extraction pesticide analysis. Moreover, deep eutectic solvents (DES) made components natural origin, have been applied microextraction as green alternative solvents. The combination thin film DES can be seen an OPPs from water samples. We describe microextraction-GC-MS method determination was prepared by casting using cellulose triacetate (CTA) polymer extracting phase. Lidocaine, menthol, dodecanoic acid, camphor tested DES-based film. With containing 70 % (w) CTA 30 acid:lidocaine, quantitative results mix achieved. Then, elution performed with 2 mL ethyl acetate. validation TFME piece suspended 20 sample solution contact time 1 h. Limits detection low μg L−1 range obtained single quadrupole mass analyser. pipette tip configuration preliminary chlorpyrifos satisfactory. This represents first approach use polymeric films OPPs, two tip.

Language: Английский

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