Infectious Diseases Associated with Exposure to Pollutants in a Local Population from Mexico DOI Creative Commons
Amparo Mauricio-Gutiérrez, Omar Romero‐Arenas, José Víctor Tamariz-Flores

et al.

Applied Sciences, Journal Year: 2023, Volume and Issue: 13(23), P. 12754 - 12754

Published: Nov. 28, 2023

Agriculture is one of the primary activities in municipality Acatzingo, Puebla, Mexico. Agricultural fields are affected by indiscriminate use pesticides and hydrocarbon spills, which expose inhabitants to development infectious diseases. In present study, we assessed likelihood developing diseases associated with environmental contamination (pesticides hydrocarbons) various areas A questionnaire was applied 425 people four two locations divided according exposure hydrocarbons pesticides. We conducted a binomial analysis using binary logistic regression model, odds ratio (OR) calculated at p ≤ 0.05. The significantly geographical zone (p = 0.001). population Acatzingo de Hidalgo had higher predicted probability (54.8%) infections. Zone 3, exposed hydrocarbons, twice contracting infections (OR 1.833, 0.093). Factors such as tobacco or alcohol consumption, gender, age did not influence However, minors, businesspeople, individuals chronic degenerative were more likely contract Therefore, it crucial implement control regulation managing spills mitigate risks human health.

Language: Английский

Ecological impacts and management strategies of pesticide pollution on aquatic life and human beings DOI
Synan F. AbuQamar, Mohamed T. El‐Saadony, Samar Sami Alkafaas

et al.

Marine Pollution Bulletin, Journal Year: 2024, Volume and Issue: 206, P. 116613 - 116613

Published: July 24, 2024

Language: Английский

Citations

26

Strategies for mitigation of pesticides from the environment through alternative approaches: A review of recent developments and future prospects DOI
Veena Chaudhary, Mukesh Kumar, Chetan Chauhan

et al.

Journal of Environmental Management, Journal Year: 2024, Volume and Issue: 354, P. 120326 - 120326

Published: Feb. 21, 2024

Language: Английский

Citations

17

Mechanisms of Neurotoxicity of Organophosphate Pesticides and Their Relation to Neurological Disorders DOI Creative Commons
Yixin Chen, Zhuo Yang,

Bin Nian

et al.

Neuropsychiatric Disease and Treatment, Journal Year: 2024, Volume and Issue: Volume 20, P. 2237 - 2254

Published: Nov. 1, 2024

Organophosphates (OPs) refers to a diverse group of phosphorus-containing organic compounds; they are widely used all over the world and have had an important beneficial impact on industrial agricultural production control vector transmission. Exposure OPs different toxicities (high, moderate, slight, low toxicity) can negative consequences nervous system, such as nausea, vomiting, muscle tremors, convulsions. In severe cases, it lead respiratory failure or even death. Notably, induce neuropathy in system through specific interactions with nicotinic muscarinic receptors, phosphorylating acetylcholinesterase, neuropathic target esterases. This review summarizes possible toxicological mechanisms their interplay underlying OP pesticide poisoning, including cholinesterase inhibition non-cholinesterase mechanisms. It outlines links between poisoning neurological disorders, dementia, neurodevelopmental diseases, Parkinson's disease. Additionally, explores interactions' potential therapeutic implications that may help mitigate deleterious system.

Language: Английский

Citations

7

Organic Food Consumption Might Protect Against Sensitisation to Inhalant Allergens at School Age: The PARIS Cohort DOI Creative Commons
Maëlys Pernin‐Schneider, Hélène Amazouz, Guillaume Lezmi

et al.

Allergy, Journal Year: 2025, Volume and Issue: 80(1), P. 258 - 270

Published: Jan. 1, 2025

Interest has grown recently in childhood diet's role allergy development. However, the studies focusing on organic food consumption are scarce. We address relationships between such and respiratory/allergic morbidity at school age PARIS (Pollution asthma risk: An infant study) cohort. Diet was assessed using a frequency questionnaire completed by parents 8 years. Dietary patterns were identified cluster analysis based of 30 foods (either or conventional) 19 foods. Associations dietary (asthma, rhinitis, eczema sensitisation) studied multivariable logistic regression models adjusted for potential confounders, including family socioeconomic status adherence to Mediterranean diet as proxy balance. Among 1258 children, three identified, which differed significantly terms frequency: low G0 (51% children), moderate G1 (28%) high G2 (21%). No association found asthma, eczema, rhinitis sensitisation allergens. Children had lower likelihood any allergen than those (adjusted odds ratio [aOR] = 0.60; 95% confidence interval [CI]: 0.40-0.91), particularly inhalant allergens (aOR 0.64; CI: 0.42-0.99). Our findings suggest that frequent may be protective against allergic age, assumption eight reflects earlier ages. Further research is warranted explore underlying mechanisms this association, nutritional environmental exposures.

Language: Английский

Citations

0

In vitro immunotoxic evaluation of herbicides in RAW 264.7 cells DOI
Larissa Vivan Cestonaro, A Conte, Fernanda Capitânio Goldoni

et al.

Journal of Toxicology and Environmental Health, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 14

Published: Jan. 15, 2025

Weeds are a concern in agriculture and the use of herbicides constitutes an effective, efficient, economical way to control their growth. Recent discoveries promising for management resistant weeds. However, there is gap knowledge toxic effects some previously reported on immune cells. The present study aimed examine cellular immunotoxicity three (clomazone, glyphosate, sulfentrazone) after 96 hr incubation utilizing RAW 264.7 BALB/c mouse monocyte/macrophage-like cell line elucidate role toxicological pathways. Data demonstrated clomazone, sulfentrazone initiated cytotoxic effect as evidenced by EC50 values 429.2; 53.7; 866.6 mg/L, respectively. Clomazone sulfentrazone, at all concentrations, induced excess production reactive oxygen (ROS) nitrogen (RNS) free radicals. An immunosuppression was observed cells with 50 or 100 mg/L glyphosate 500 1000 sulfentrazone. In addition, produced mitochondrial depolarization decreased tumor necrosis factor-α (TNF-α) levels. This first report clomazone cells, including reduced TNF-α levels, indicating adverse influence system.

Language: Английский

Citations

0

Fipronil in sub-lethal doses leads to immuno-toxicological effects in broiler birds DOI Creative Commons
Shafia Tehseen Gul, Muhammad Nawaz Tahir, Latif Ahmad

et al.

PLoS ONE, Journal Year: 2025, Volume and Issue: 20(1), P. e0315915 - e0315915

Published: Jan. 28, 2025

Pesticides, including fipronil, are used mainly in agriculture; however, veterinary and animal husbandry, their potential use is to control the pests responsible for vector-borne diseases. Their residues agriculture products direct on farms potentially harming livestock poultry. So, this study was designed evaluate toxico-pathological effects of fipronil immune system poultry birds. One hundred a-day-old chicks were purchased from a local hatchery, standard housing conditions provided brooding till end trail. The temperature at kept 33°C; later on, it maintained 26–28°C, humidity 60–70%. Clean water basal diet ad libitum . After three days acclimatization, birds divided into five experimental groups (A E), each containing 20 Group A as group. Fipronil administered orally through crop tubing @ 1.5, 2.5, 3.5, 4.5 mg/kg B-E, respectively. Birds euthanized humanely 15 th , 30 45 experiment. Immunological parameters evaluated, i.e., antibody titers against NDV SRBCs, phagocytic activity clear carbon particles, avian incompetence tuberculin, histopathological alterations lymphoid organs. SAS ® University Edition software data analysis. results indicated decreased treatment compared control. Similarly, response clearing sensitivity tuberculin also decreased. Results revealed that bursa Fabricius thymus spleen affected due toxic effect even sub-lethal doses.

Language: Английский

Citations

0

Repeated exposure to trichlorphone caused death in a young cat DOI Open Access

Zulfa Aisyah Nur'aeni,

Rina Juwita,

Sarasati Windria

et al.

ARSHI Veterinary Letters, Journal Year: 2025, Volume and Issue: 9(1), P. 7 - 8

Published: Feb. 12, 2025

A 4-month-old Persian cat was brought to the Zoom Veterinary Clinic because it had seizures after using insecticide containing trichlorfon. After a physical examination, found that seizures, hypersalivation, and cyanosis of gums ears. Hematology blood biochemistry tests were performed. The hematology results showed an increase in white cells, while glucose, SGPT, calcium, amylase decrease creatinine. first treatment given atropine sulfate, ornipural, Ringer lactate infusion. that, cat's condition improved, but again. hospitalized at received therapy form diazepam, cefotaxime, infusion, furosemide, Novifit®. On 2nd day hospitalization, died.

Language: Английский

Citations

0

Association between organophosphate pesticide exposure and atopic dermatitis: a cross-sectional study based on NHANES 1999–2007 DOI Creative Commons

YueHua Men,

Y. C. Wang,

Wen‐Chih Wu

et al.

Frontiers in Public Health, Journal Year: 2025, Volume and Issue: 13

Published: March 6, 2025

Organophosphate pesticides (OPPs) are widely used environmental chemicals with potential health impacts, but their relationship atopic dermatitis (AD) remains unclear. Using data from the National Health and Nutrition Examination Survey (NHANES) 1999-2007, we investigated associations between urinary OPP metabolites AD in 4,258 adults. Six dialkyl phosphate (DAP) were measured, weighted quantile sum (WQS) regression was to assess mixture effects. Both DMP (odds ratio [OR] = 1.17, 95% confidence interval [CI]: 1.05-1.31) DMDTP (OR 2.23, 95%CI: 1.08-4.60) showed significant positive fully adjusted models. WQS revealed mixed exposure 1.25, 1.04-1.50), contributing most (45.8%) effect. Stratified analyses indicated stronger males, younger adults (<60 years), smokers. Our findings suggest that exposure, particularly DMP, may be associated increased risk These results provide new insights into factors for AD.

Language: Английский

Citations

0

Assessment of organophosphate pesticides in soils and vegetables from agricultural areas of Delta Central District, Nigeria DOI Creative Commons
Godswill O. Tesi, Kingsley Ezechukwu Okpara,

Juliet Ngozi Tesi

et al.

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: March 10, 2025

The application of agrochemicals such as organophosphate pesticides (OPPs) has several benefits in agriculture but also poses great risks to the environment and human well-being. Thus, this study was conducted determine concentrations, distribution pattern, relationships, potential sources OPPs agricultural soils vegetables from Delta Central District (DCD) Nigeria provide useful information for pollution history, establishment control measures risk management. Fourteen were determined soil using a gas chromatograph-mass selective detector (GC-MSD). ∑14 concentrations varied 5.29 419 ng g−1 0.69 130 vegetables. On average, pirimiphos methyl (23.8 g−1) diazinone (4.74 dominant respectively. cumulative ecological assessed toxicity-exposure-ratio (TER) quotient (RQ) approaches revealed that there high organisms. increasing order toxicity organisms chlorpyriphos < fenitrothion while health suggested adverse non-carcinogenic children not adults exposed these

Language: Английский

Citations

0

Transcriptome Analysis Reveals Differential Gene Regulation in Ovarian Tissues of Anabas testudineus (Bloch, 1792) in Response to Insecticide, Monocrotophos DOI

Siyag Dhere,

Pokanti Vinay Kumar,

Kiran D. Rasal

et al.

Marine Biotechnology, Journal Year: 2025, Volume and Issue: 27(2)

Published: March 18, 2025

Language: Английский

Citations

0