Applied Sciences,
Journal Year:
2023,
Volume and Issue:
13(23), P. 12754 - 12754
Published: Nov. 28, 2023
Agriculture
is
one
of
the
primary
activities
in
municipality
Acatzingo,
Puebla,
Mexico.
Agricultural
fields
are
affected
by
indiscriminate
use
pesticides
and
hydrocarbon
spills,
which
expose
inhabitants
to
development
infectious
diseases.
In
present
study,
we
assessed
likelihood
developing
diseases
associated
with
environmental
contamination
(pesticides
hydrocarbons)
various
areas
A
questionnaire
was
applied
425
people
four
two
locations
divided
according
exposure
hydrocarbons
pesticides.
We
conducted
a
binomial
analysis
using
binary
logistic
regression
model,
odds
ratio
(OR)
calculated
at
p
≤
0.05.
The
significantly
geographical
zone
(p
=
0.001).
population
Acatzingo
de
Hidalgo
had
higher
predicted
probability
(54.8%)
infections.
Zone
3,
exposed
hydrocarbons,
twice
contracting
infections
(OR
1.833,
0.093).
Factors
such
as
tobacco
or
alcohol
consumption,
gender,
age
did
not
influence
However,
minors,
businesspeople,
individuals
chronic
degenerative
were
more
likely
contract
Therefore,
it
crucial
implement
control
regulation
managing
spills
mitigate
risks
human
health.
Neuropsychiatric Disease and Treatment,
Journal Year:
2024,
Volume and Issue:
Volume 20, P. 2237 - 2254
Published: Nov. 1, 2024
Organophosphates
(OPs)
refers
to
a
diverse
group
of
phosphorus-containing
organic
compounds;
they
are
widely
used
all
over
the
world
and
have
had
an
important
beneficial
impact
on
industrial
agricultural
production
control
vector
transmission.
Exposure
OPs
different
toxicities
(high,
moderate,
slight,
low
toxicity)
can
negative
consequences
nervous
system,
such
as
nausea,
vomiting,
muscle
tremors,
convulsions.
In
severe
cases,
it
lead
respiratory
failure
or
even
death.
Notably,
induce
neuropathy
in
system
through
specific
interactions
with
nicotinic
muscarinic
receptors,
phosphorylating
acetylcholinesterase,
neuropathic
target
esterases.
This
review
summarizes
possible
toxicological
mechanisms
their
interplay
underlying
OP
pesticide
poisoning,
including
cholinesterase
inhibition
non-cholinesterase
mechanisms.
It
outlines
links
between
poisoning
neurological
disorders,
dementia,
neurodevelopmental
diseases,
Parkinson's
disease.
Additionally,
explores
interactions'
potential
therapeutic
implications
that
may
help
mitigate
deleterious
system.
Allergy,
Journal Year:
2025,
Volume and Issue:
80(1), P. 258 - 270
Published: Jan. 1, 2025
Interest
has
grown
recently
in
childhood
diet's
role
allergy
development.
However,
the
studies
focusing
on
organic
food
consumption
are
scarce.
We
address
relationships
between
such
and
respiratory/allergic
morbidity
at
school
age
PARIS
(Pollution
asthma
risk:
An
infant
study)
cohort.
Diet
was
assessed
using
a
frequency
questionnaire
completed
by
parents
8
years.
Dietary
patterns
were
identified
cluster
analysis
based
of
30
foods
(either
or
conventional)
19
foods.
Associations
dietary
(asthma,
rhinitis,
eczema
sensitisation)
studied
multivariable
logistic
regression
models
adjusted
for
potential
confounders,
including
family
socioeconomic
status
adherence
to
Mediterranean
diet
as
proxy
balance.
Among
1258
children,
three
identified,
which
differed
significantly
terms
frequency:
low
G0
(51%
children),
moderate
G1
(28%)
high
G2
(21%).
No
association
found
asthma,
eczema,
rhinitis
sensitisation
allergens.
Children
had
lower
likelihood
any
allergen
than
those
(adjusted
odds
ratio
[aOR]
=
0.60;
95%
confidence
interval
[CI]:
0.40-0.91),
particularly
inhalant
allergens
(aOR
0.64;
CI:
0.42-0.99).
Our
findings
suggest
that
frequent
may
be
protective
against
allergic
age,
assumption
eight
reflects
earlier
ages.
Further
research
is
warranted
explore
underlying
mechanisms
this
association,
nutritional
environmental
exposures.
Journal of Toxicology and Environmental Health,
Journal Year:
2025,
Volume and Issue:
unknown, P. 1 - 14
Published: Jan. 15, 2025
Weeds
are
a
concern
in
agriculture
and
the
use
of
herbicides
constitutes
an
effective,
efficient,
economical
way
to
control
their
growth.
Recent
discoveries
promising
for
management
resistant
weeds.
However,
there
is
gap
knowledge
toxic
effects
some
previously
reported
on
immune
cells.
The
present
study
aimed
examine
cellular
immunotoxicity
three
(clomazone,
glyphosate,
sulfentrazone)
after
96
hr
incubation
utilizing
RAW
264.7
BALB/c
mouse
monocyte/macrophage-like
cell
line
elucidate
role
toxicological
pathways.
Data
demonstrated
clomazone,
sulfentrazone
initiated
cytotoxic
effect
as
evidenced
by
EC50
values
429.2;
53.7;
866.6
mg/L,
respectively.
Clomazone
sulfentrazone,
at
all
concentrations,
induced
excess
production
reactive
oxygen
(ROS)
nitrogen
(RNS)
free
radicals.
An
immunosuppression
was
observed
cells
with
50
or
100
mg/L
glyphosate
500
1000
sulfentrazone.
In
addition,
produced
mitochondrial
depolarization
decreased
tumor
necrosis
factor-α
(TNF-α)
levels.
This
first
report
clomazone
cells,
including
reduced
TNF-α
levels,
indicating
adverse
influence
system.
PLoS ONE,
Journal Year:
2025,
Volume and Issue:
20(1), P. e0315915 - e0315915
Published: Jan. 28, 2025
Pesticides,
including
fipronil,
are
used
mainly
in
agriculture;
however,
veterinary
and
animal
husbandry,
their
potential
use
is
to
control
the
pests
responsible
for
vector-borne
diseases.
Their
residues
agriculture
products
direct
on
farms
potentially
harming
livestock
poultry.
So,
this
study
was
designed
evaluate
toxico-pathological
effects
of
fipronil
immune
system
poultry
birds.
One
hundred
a-day-old
chicks
were
purchased
from
a
local
hatchery,
standard
housing
conditions
provided
brooding
till
end
trail.
The
temperature
at
kept
33°C;
later
on,
it
maintained
26–28°C,
humidity
60–70%.
Clean
water
basal
diet
ad
libitum
.
After
three
days
acclimatization,
birds
divided
into
five
experimental
groups
(A
E),
each
containing
20
Group
A
as
group.
Fipronil
administered
orally
through
crop
tubing
@
1.5,
2.5,
3.5,
4.5
mg/kg
B-E,
respectively.
Birds
euthanized
humanely
15
th
,
30
45
experiment.
Immunological
parameters
evaluated,
i.e.,
antibody
titers
against
NDV
SRBCs,
phagocytic
activity
clear
carbon
particles,
avian
incompetence
tuberculin,
histopathological
alterations
lymphoid
organs.
SAS
®
University
Edition
software
data
analysis.
results
indicated
decreased
treatment
compared
control.
Similarly,
response
clearing
sensitivity
tuberculin
also
decreased.
Results
revealed
that
bursa
Fabricius
thymus
spleen
affected
due
toxic
effect
even
sub-lethal
doses.
ARSHI Veterinary Letters,
Journal Year:
2025,
Volume and Issue:
9(1), P. 7 - 8
Published: Feb. 12, 2025
A
4-month-old
Persian
cat
was
brought
to
the
Zoom
Veterinary
Clinic
because
it
had
seizures
after
using
insecticide
containing
trichlorfon.
After
a
physical
examination,
found
that
seizures,
hypersalivation,
and
cyanosis
of
gums
ears.
Hematology
blood
biochemistry
tests
were
performed.
The
hematology
results
showed
an
increase
in
white
cells,
while
glucose,
SGPT,
calcium,
amylase
decrease
creatinine.
first
treatment
given
atropine
sulfate,
ornipural,
Ringer
lactate
infusion.
that,
cat's
condition
improved,
but
again.
hospitalized
at
received
therapy
form
diazepam,
cefotaxime,
infusion,
furosemide,
Novifit®.
On
2nd
day
hospitalization,
died.
Frontiers in Public Health,
Journal Year:
2025,
Volume and Issue:
13
Published: March 6, 2025
Organophosphate
pesticides
(OPPs)
are
widely
used
environmental
chemicals
with
potential
health
impacts,
but
their
relationship
atopic
dermatitis
(AD)
remains
unclear.
Using
data
from
the
National
Health
and
Nutrition
Examination
Survey
(NHANES)
1999-2007,
we
investigated
associations
between
urinary
OPP
metabolites
AD
in
4,258
adults.
Six
dialkyl
phosphate
(DAP)
were
measured,
weighted
quantile
sum
(WQS)
regression
was
to
assess
mixture
effects.
Both
DMP
(odds
ratio
[OR]
=
1.17,
95%
confidence
interval
[CI]:
1.05-1.31)
DMDTP
(OR
2.23,
95%CI:
1.08-4.60)
showed
significant
positive
fully
adjusted
models.
WQS
revealed
mixed
exposure
1.25,
1.04-1.50),
contributing
most
(45.8%)
effect.
Stratified
analyses
indicated
stronger
males,
younger
adults
(<60
years),
smokers.
Our
findings
suggest
that
exposure,
particularly
DMP,
may
be
associated
increased
risk
These
results
provide
new
insights
into
factors
for
AD.
Scientific Reports,
Journal Year:
2025,
Volume and Issue:
15(1)
Published: March 10, 2025
The
application
of
agrochemicals
such
as
organophosphate
pesticides
(OPPs)
has
several
benefits
in
agriculture
but
also
poses
great
risks
to
the
environment
and
human
well-being.
Thus,
this
study
was
conducted
determine
concentrations,
distribution
pattern,
relationships,
potential
sources
OPPs
agricultural
soils
vegetables
from
Delta
Central
District
(DCD)
Nigeria
provide
useful
information
for
pollution
history,
establishment
control
measures
risk
management.
Fourteen
were
determined
soil
using
a
gas
chromatograph-mass
selective
detector
(GC-MSD).
∑14
concentrations
varied
5.29
419
ng
g−1
0.69
130
vegetables.
On
average,
pirimiphos
methyl
(23.8
g−1)
diazinone
(4.74
dominant
respectively.
cumulative
ecological
assessed
toxicity-exposure-ratio
(TER)
quotient
(RQ)
approaches
revealed
that
there
high
organisms.
increasing
order
toxicity
organisms
chlorpyriphos
<
fenitrothion
while
health
suggested
adverse
non-carcinogenic
children
not
adults
exposed
these
