Multiple Biological Mechanisms for the Potential Influence of Phytochemicals on Physical Activity Performance: A Narrative Review DOI Creative Commons
Robert Thomas,

Madeleine Williams,

Jeffrey Aldous

et al.

Nutraceuticals, Journal Year: 2023, Volume and Issue: 3(3), P. 353 - 365

Published: July 11, 2023

Natural phytochemicals (PCs) are responsible for the taste, colour, and aroma of many edible plants. Cohort studies have linked higher intake to a reduced risk chronic degenerative diseases premature ageing. The ability foods rich in PCs, such as phytanthocyanins, apigenin, flavonols, flavonoids, bioflavonoids, gallic acid, ellagic quercetin, ellagitannins, support physical activity has also been highlighted number published pre-clinical prospective clinical studies. This literature mostly emphasises PCs enhance adaptive upregulation antioxidant enzymes (AEs), which reduces exercise-associated oxidative stress, but there several other mechanisms benefit that this narrative review addresses. These include; protecting joints tendons from trauma during exercise; mitigating delayed-onset muscle symptoms (DOMS) damage; improving tissue oxygenation training; cultivating healthy gut microbiome hence lowering excess inflammation; cutting incidence upper respiratory tract viral infections disrupt training programmes; helping restore circadian rhythm improves sleep recovery daytime fatigue, turn elevates mood motivation train.

Language: Английский

The therapeutic effects of salvianolic acids on ischemic stroke: From molecular mechanisms to clinical applications DOI Creative Commons
Chao Zhao, Xiaodan Bai, Aidong Wen

et al.

Pharmacological Research, Journal Year: 2024, Volume and Issue: unknown, P. 107527 - 107527

Published: Nov. 1, 2024

Language: Английский

Citations

3
Potential Role of Dietary Phenolic Compounds in the Prevention and Treatment of Rheumatoid Arthritis: Current Reports DOI Creative Commons
Ana C. Gonçalves, S. Sofia M. Rodrigues, Rafael Fonseca

et al.

Pharmaceuticals, Journal Year: 2024, Volume and Issue: 17(5), P. 590 - 590

Published: May 6, 2024

Rheumatoid arthritis (RA) is a complex illness with both hereditary and environmental components. Globally, in 2019, 18 million people had RA. RA characterized by persistent inflammation of the synovial membrane that lines joints, cartilage loss, bone erosion. Phenolic molecules are most prevalent secondary metabolites plants, diverse spectrum biological actions benefit functional meals nutraceuticals. These compounds have received lot attention recently because they antioxidant, anti-inflammatory, immunomodulatory, anti-rheumatoid activity modulating tumor necrosis factor, mitogen-activated protein kinase, nuclear factor kappa-light-chain-enhancer activated B cells, c-Jun N-terminal kinases, as well other preventative properties. This article discusses dietary polyphenols, their pharmacological properties, innovative delivery technologies for treatment RA, focus on possible activities. Nonetheless, commercialization polyphenols may be achievable only after confirming safety profile completing successful clinical trials.

Language: Английский

Citations

2
Effects of Polyphenol Consumption on Recovery in Team Sport Athletes of Both Sexes: A Systematic Review DOI Open Access

Mariana Sánchez Díaz,

Adrián Martín-Castellanos, Valentín E. Fernández-Elías

et al.

Nutrients, Journal Year: 2022, Volume and Issue: 14(19), P. 4085 - 4085

Published: Oct. 1, 2022

Previous studies have shown that polyphenol consumption enhances recovery of the muscle after exercise-induced damage (EIMD). However, EIMD markers not been studied by sport type. The main aim this research was to perform a systematic review determine efficacy polyphenolic in increasing for performing team skills. Eligible included, following PICOS structure, presented at least one outcomes: maximal isometric voluntary contraction (MVIC); countermovement jump (CMJ); delayed onset soreness (DOMS); 20 m sprint test; creatine kinase (CK); and C-reactive protein (hsCRP). A structured search carried out Preferred Reporting Items Systematic Review Meta-Analyses (PRISMA) guidelines. risk bias assessed using PEDro scale tool. showed possibly positive impact on sports athletes. No differences were found between sexes. Considering limitations, there is moderate very low certainty supplementation effects females males. dose 60 mL/day, divided into two times per day, ingested >7 days may present function further investigation required, specifically females.

Language: Английский

Citations

11
Continuous Monitoring of Psychosocial Stress by Non-Invasive Volatilomics DOI
Elias Mansour,

Walaa Saliba,

Yoav Y. Broza

et al.

ACS Sensors, Journal Year: 2023, Volume and Issue: 8(8), P. 3215 - 3224

Published: July 26, 2023

Stress is becoming increasingly commonplace in modern times, making it important to have accurate and effective detection methods. Currently, methods such as self-evaluation clinical questionnaires are subjective unsuitable for long-term monitoring. There been significant studies into biomarkers HRV, cortisol, electrocardiography, blood biomarkers, but the use of multiple electrodes electrocardiography or tests impractical real-time stress To this end, there a need non-invasive sensors monitor real time. This study looks at possibility using breath skin VOC fingerprinting biomarkers. The Trier social test (TSST) was used induce acute anxiety levels were measured before, during, after test. GC-MS sensor array collect measure VOCs. A prediction model found eight different stress-related VOCs with an accuracy up 78%, molecularly capped gold nanoparticle-based revealed difference fingerprints between two groups. These either changed returned baseline induction, suggesting metabolic pathways times. correlation analysis association cortisol weak HRV levels, that may include complementary information detection. shows potential paving way developing real-time, objective, tool well-being early diseases.

Language: Английский

Citations

5
Sleep and Nutrition in Athletes DOI
Rónán Doherty, Sharon M. Madigan, Giles Warrington

et al.

Current Sleep Medicine Reports, Journal Year: 2023, Volume and Issue: 9(1), P. 82 - 89

Published: Jan. 7, 2023

Language: Английский

Citations

4
Development, characterization and stability of a novel sport drink based on thermal water, apple juice and hibiscus DOI Creative Commons

Maroua Fatma Radhouane,

Tayse Ferreira Ferreira da Silveira, Jessica Ribeiro

et al.

Food Chemistry Advances, Journal Year: 2024, Volume and Issue: unknown, P. 100823 - 100823

Published: Sept. 1, 2024

Language: Английский

Citations

1
Hydrogen-Rich Water to Enhance Exercise Performance: A Review of Effects and Mechanisms DOI Creative Commons

Qiaorui Zhou,

Huixin Li, Ye Zhang

et al.

Metabolites, Journal Year: 2024, Volume and Issue: 14(10), P. 537 - 537

Published: Oct. 7, 2024

: Hydrogen-rich water (HRW) has garnered significant interest within the sports and exercise science community due to its selective antioxidant properties. Despite potential benefits, comprehensive reviews specifically addressing effects on athletic performance are limited. This review aims assess impact of HRW explore underlying molecular biological mechanisms, with goal elucidating how might enhance performance.

Language: Английский

Citations

1
The Effect of Aerobic Exercise on Oxidative Stress in Skeletal Muscle Tissue: A Narrative Review DOI Open Access
Elham Shamsnia, Hasan Matinhomaee, Mohammad Ali Azarbayjani

et al.

Gene Cell and Tissue, Journal Year: 2023, Volume and Issue: 10(4)

Published: Jan. 14, 2023

Context: Performing intense aerobic exercise leads to an increase in the level of reactive oxygen species (ROS) and a decrease antioxidant enzymes body tissues, especially skeletal muscles, ultimately oxidative stress. Therefore, it is very important measure stress before causes damage cells destroys them. Evidence Acquisition: In this review, 92 articles were studied between 2012 2022, which 54 used. The search was done Google Scholar, PubMed, Science Direct, SID databases. An electronic studies using keywords ROS, training, exercise, stress, defense, muscle, nuclear factor-erythroid 2-related factor 2 (NRF2). Results: review conducted field adaptations muscle shows that intensity duration activity are main factors controlling (creating or preventing) tissue. Also, taking supplements ROS levels reach peak physiological performance can reduce beneficial effects exercise. On other hand, treatment, after maximal related lead reduced fatigue and/or improved performance. Conclusions: It seems caused by function amount production internal external defense capacity individual. However, different types along with various need be performed for long time people order achieve better approaches early prediction reducing destructive muscle.

Language: Английский

Citations

3
The Effect of Aerobic Exercise and Bitter Orange Peel Extract on Oxidative Biomarkers and the Nrf2-Keap1 Signaling Pathway in the Quadriceps Tissue of Male Rats Fed a High-Fat Diet DOI Open Access
Elham Shamsnia, Hasan Matinhomaee, Mohammad Ali Azarbayjani

et al.

Gene Cell and Tissue, Journal Year: 2023, Volume and Issue: In Press(In Press)

Published: Oct. 24, 2023

Background: There appears to be a relationship between high-fat diet (HFD), inactivity, obesity, and many diseases. The effects of aerobic exercise (AE) on the improvement oxidative stress have been confirmed, antioxidant bitter orange peel (BOP) identified. Objectives: This study aimed explore synergistic 4 weeks AE BOP extract consumption biomarkers Nrf2-Keap1 signaling pathway in quadriceps tissue male rats fed an HFD. Methods: In this experimental trial, 30 were randomly divided into 5 groups: (1) control-normal (CO-ND), (2) CO-HFD, (3) AE, (4) BOP, (5) interaction (AE-BOP). group received 60 mg (per kg body weight) daily during intervention period. program with moderate intensity was implemented for weeks, days week. Results: nuclear factor erythroid 2 (NRF2) gene expression significantly increased AE-BOP groups, but increase not significant group. decrease KEAP1 studied groups significant. A MDA activity superoxide dismutase (SOD) catalase (CAT) enzymes glutathione peroxidase (GPX) observed groups. Conclusions: Aerobic reduced caused by HFD regulating NRF2-KEAP1 pathway. Therefore, these two interventions are recommended conditions

Language: Английский

Citations

3
Alleviation of Cognitive and Physical Fatigue with Enzymatic Porcine Placenta Hydrolysate Intake through Reducing Oxidative Stress and Inflammation in Intensely Exercised Rats DOI Creative Commons

Min Ju Kim,

Ting Zhang,

Keun Nam Kim

et al.

Biology, Journal Year: 2022, Volume and Issue: 11(12), P. 1739 - 1739

Published: Nov. 29, 2022

Intense exercise is reported to induce physical and cognitive fatigue, but few studies have focused on treatments alleviate fatigue. We hypothesized that the oral supplementation of enzymatic porcine placenta hydrolysate (EPPH) prepared using protease enzymes could exercise-induced fatigue in an animal model. The objectives study were examine hypothesis action mechanism EPPH relieving Fifty male Sprague–Dawley rats aged 8 weeks (body weight: 201 g) classified into five groups, each group given distilled water, (5 mg nitrogen/mL) at doses 0.08, 0.16, or 0.31 mL/kg body weight (BW)/day, glutathione (100 mg/kg BW/day) by a feeding needle for 5 weeks, which named as control, L-EPPH, M-EPPH, H-EPPH, positive-control respectively. Ten additional had no intense with water administration designated no-exercise group. After 2 subjected forced swimming trial 30 min once per week 4 weeks. At after exercise, lactate concentrations dehydrogenase (LDH) activity serum gastrocnemius muscle higher control group, whereas M-EPPH H-EPPH suppressed increase better than (p < 0.05). decreased glycogen content liver muscle, inhibited decrement Moreover, lipid peroxide contents positive-control, groups However, antioxidant enzyme activities such superoxide dismutase (SOD) peroxidase (GSH-Px) opposite contents. Hypothalamic corticosterone hippocampal mRNA expressions tumor necrosis factor (TNF)-α IL-1β higher. brain-derived neurotrophic (BDNF) expression protein lower changes via activating cAMP response element-binding phosphorylation, showed In conclusion, (0.16–0.31 BW) intake reduced potentially be developed therapeutic agent humans.

Language: Английский

Citations

4