A sulfated exopolysaccharide from Bacillus altitudinis MTCC13046 accelerates cutaneous wound healing via dermal fibroblast migration: Insights into an in vivo wound re-epithelialization DOI

S. Asharaf,

Kajal Chakraborty,

Silpa Kunnappilly Paulose

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 141001 - 141001

Published: Feb. 1, 2025

Language: Английский

Natural polymers used in the dressing materials for wound healing: Past, present and future DOI Open Access

Bharti Sheokand,

Monika Vats, Anand Kumar

et al.

Journal of Polymer Science, Journal Year: 2023, Volume and Issue: 61(14), P. 1389 - 1414

Published: March 27, 2023

Abstract Wound healing is a complicated system that necessitates an appropriate environment to aid healing. dressing among the most important external variables in wound repair. Technology advancements have led creation of variety dressings treat various types by focusing on four stages Simplicity application, sterility, antibacterial, non‐adherent, gaseous exchange, non‐toxicity, and other qualities are necessary for dressings. In order fully regenerate restore structure functionality skin, ideal should address demands wound. So, kind used based type injury. This review focuses different natural polymers such as κ‐carrageenan, chitosan, cellulose, gelatin, collagen, alginate, hyaluronic acid, silk fibroin development materials hydrogels, nanofibers, sponges, films, scaffolds owing their features, example, biocompatibility, biodegradability, similarity human extracellular matrix (ECM) which aids process. The commercially available products these also discussed review. However, majority polymer‐based still exhibit number problems like adherence, opaque, fast degradability, lack multifunctionality, thus need be addressed. A naturally inspired smart hour individual monitoring multiple pH, temperature, electrical potentials eases incorporated drug biological molecules per progress with delivery systems.

Language: Английский

Citations

73

Natural and Synthetic Polymeric Biomaterials for Application in Wound Management DOI Creative Commons

Sabrina Prete,

Marco Dattilo, Francesco Patitucci

et al.

Journal of Functional Biomaterials, Journal Year: 2023, Volume and Issue: 14(9), P. 455 - 455

Published: Sept. 3, 2023

Biomaterials are at the forefront of future, finding a variety applications in biomedical field, especially wound healing, thanks to their biocompatible and biodegradable properties. Wounds spontaneously try heal through series interconnected processes involving several initiators mediators such as cytokines, macrophages, fibroblasts. The combination biopolymers with healing properties may provide opportunities synthesize matrices that stimulate trigger target cell responses crucial process. This review outlines optimal management care required for treatment special focus on biopolymers, drug-delivery systems, nanotechnologies used enhanced applications. Researchers have utilized range techniques produce dressings, leading products different characteristics. Each method comes its unique strengths limitations, which important consider. future trajectory dressing advancement should prioritize economical eco-friendly methodologies, along improving efficacy constituent materials. aim this work is give researchers possibility evaluate proper materials preparation better understand synthesis conditions well most effective bioactive molecules load.

Language: Английский

Citations

63

Recent advances in modified poly (lactic acid) as tissue engineering materials DOI Creative Commons

Samanta Castañeda-Rodríguez,

Maykel González‐Torres, Rosa María Ribas‐Aparicio

et al.

Journal of Biological Engineering, Journal Year: 2023, Volume and Issue: 17(1)

Published: March 20, 2023

Abstract As an emerging science, tissue engineering and regenerative medicine focus on developing materials to replace, restore or improve organs tissues enhancing the cellular capacity proliferate, migrate differentiate into different cell types specific tissues. Renewable resources have been used develop new materials, resulting in attempts produce various environmentally friendly biomaterials. Poly (lactic acid) (PLA) is a biopolymer known be biodegradable it produced from fermentation of carbohydrates. PLA can combined with other polymers biomaterials suitable physicochemical properties for applications. Here, advances modified as are discussed light its drawbacks, such biological inertness, low adhesion, degradation rate, efforts conducted address these challenges toward design enhanced alternative

Language: Английский

Citations

53

Synergistically self-assembled 2D nanosheets of MXene@MOF derived CoW-LDH into 3D frameworks functionalized with chitosan for improved skin wound healing DOI
K. Kasirajan, Young‐Kwon Park, Balasubramani Ravindran

et al.

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 482, P. 149088 - 149088

Published: Jan. 26, 2024

Language: Английский

Citations

20

Innovative Approaches to Wound Healing: Insights into Interactive Dressings and Future Directions DOI
Radhika Yadav, Rohtash Kumar,

Muskan Kathpalia

et al.

Journal of Materials Chemistry B, Journal Year: 2024, Volume and Issue: 12(33), P. 7977 - 8006

Published: Jan. 1, 2024

The objective of this review is to provide an up-to-date and all-encompassing account the recent advancements in domain interactive wound dressings. Considering gap between achieved desired clinical outcomes with currently available or under-study healing therapies, newer more specific options based on type phase are reviewed. Starting from comprehensive description process, a detailed classification dressings presented. Subsequently, we present elaborate significant discussion describing (unconventional) Latter includes biopolymer-based, bioactive-containing biosensor-based smart dressings, which discussed separate sections together their applications limitations. Moreover, (2-5 years) trials, patents unconventional marketed products, other information advanced care designs techniques discussed. future research direction highlighted, peptides, proteins, human amniotic membranes as potential Finally, conclude that field needs further development offers scope for integrating process technologies.

Language: Английский

Citations

17

Progress in Wound-Healing Products Based on Natural Compounds, Stem Cells, and MicroRNA-Based Biopolymers in the European, USA, and Asian Markets: Opportunities, Barriers, and Regulatory Issues DOI Open Access
Girish K. Srivastava,

Sofia Martinez-Rodriguez,

Nur Izzah Md Fadilah

et al.

Polymers, Journal Year: 2024, Volume and Issue: 16(9), P. 1280 - 1280

Published: May 3, 2024

Wounds are breaks in the continuity of skin and underlying tissues, resulting from external causes such as cuts, blows, impacts, or surgical interventions. Countless individuals suffer minor to severe injuries, with unfortunate cases even leading death. In today’s scenario, several commercial products available facilitate healing process wounds, although chronic wounds still present more challenges than acute wounds. Nevertheless, huge demand for wound-care within healthcare sector has given rise a rapidly growing market, fostering continuous research development endeavors innovative wound-healing solutions. Today, there many commercially including those based on natural biopolymers, stem cells, microRNAs that promote This article explores recent breakthroughs harness potential microRNAs. A comprehensive exploration is undertaken, covering not only but also phase. Additionally, we provide thorough examination opportunities, obstacles, regulatory considerations influencing commercialization across diverse markets Europe, America, Asia.

Language: Английский

Citations

16

Biopolymers in diabetic wound care management: A potential substitute to traditional dressings DOI Creative Commons
Sara Hasan,

Muhammad Amish Hasan,

Muhammad Hassan

et al.

European Polymer Journal, Journal Year: 2023, Volume and Issue: 189, P. 111979 - 111979

Published: March 7, 2023

The poor healing of diabetic wound affects large proportion human beings by high mortality rate and associated expenditures. Such chronic wounds mainly become problematic due to unavailability suitable environmental conditions which lead cell migration, proliferation uncontrolled inflammation. An ideal dressing should prohibit dryness allow a environment at the injury surface. However, present therapeutics lacks potential overcome these problems resulting in their limited clinical success. There is shift research domain from synthetic natural polymeric materials issues with traditional dressings. Many biological organisms' extracted polymers are useful for ease availability various active substances. naturally occurring polysaccharides proteins find several attractive applications biomedical field.These substances not only non-toxic but also possess characteristics. In this work, proteins-based biopolymers utilized recent years as material discussed. This review will surely provide guidance researchers using effective economical material.

Language: Английский

Citations

32

Emerging horizons and prospects of polysaccharide-constructed gels in the realm of wound healing DOI

Shen-Han Wu,

Lekshmi Rethi,

Wen‐Yu Pan

et al.

Colloids and Surfaces B Biointerfaces, Journal Year: 2024, Volume and Issue: 235, P. 113759 - 113759

Published: Jan. 21, 2024

Language: Английский

Citations

10

Chitosan: modification and biodegradability of by-products DOI
Great Iruoghene Edo, Emad͏͏͏͏͏͏͏͏͏͏͏͏͏͏͏͏͏͏͏ Yousif, Mohammed H. Al-Mashhadani

et al.

Polymer Bulletin, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 30, 2024

Language: Английский

Citations

10

Recycling Technologies for Biopolymers: Current Challenges and Future Directions DOI Open Access
Adenike A. Akinsemolu,

Adetola M. Idowu,

Helen Onyeaka

et al.

Polymers, Journal Year: 2024, Volume and Issue: 16(19), P. 2770 - 2770

Published: Sept. 30, 2024

Plastic pollution is a major driver of climate change that associated with biodiversity loss, greenhouse gas emissions, and negative soil, plant, animal, human health. One the solutions has been proposed currently reducing adverse effects plastic on planet replacement synthetic plastics biopolymers. The biodegradable polymers have adapted for most applications plastic. However, their use disposal present some sustainability challenges. Recycling emerges as an effective way promoting biopolymer use. In this article, we review recycling viable solution to improve biopolymers, emphasizing current types technologies employed in challenges faced adoption. Our exploration future directions conversion biopolymers into new reuse establishes connection between established continuous technological innovation, integration circular economy models, establishment strengthening collaborations among key stakeholders relevant industries necessary steps adoption, full utilization, improvement By connecting these factors, study lays foundation roadmap improved processes promote alternatives.

Language: Английский

Citations

10