International Journal of Precision Engineering and Manufacturing-Green Technology, Journal Year: 2024, Volume and Issue: 12(2), P. 691 - 717
Published: Dec. 6, 2024
Language: Английский
Frontiers in Bioengineering and Biotechnology, Journal Year: 2023, Volume and Issue: 11
Published: Feb. 14, 2023
This review presents a comprehensive summary of the latest research in field bioremediation with filamentous fungi. The main focus is on issue recent progress remediation pharmaceutical compounds, heavy metal treatment and oil hydrocarbons mycoremediation that are usually insufficiently represented other reviews. It encompasses variety cellular mechanisms involved used by fungi, including bio-adsorption, bio-surfactant production, bio-mineralization, bio-precipitation, as well extracellular intracellular enzymatic processes . Processes for wastewater accomplished through physical, biological, chemical briefly described. species diversity fungi pollutant removal, widely studied Aspergillus , Penicillium Fusarium Verticillium Phanerochaete Basidiomycota Zygomycota summarized. removal efficiency time elimination wide compounds their easy handling make them excellent tools emerging contaminants. Various types beneficial byproducts made such raw material feed food chitosan, ethanol, lignocellulolytic enzymes, organic acids, nanoparticles, discussed. Finally, challenges faced, future prospects, how innovative technologies can be to further exploit enhance abilities remediation, mentioned.
Language: Английский
Citations
61
Biomass Conversion and Biorefinery, Journal Year: 2023, Volume and Issue: 14(20), P. 25395 - 25409
Published: July 20, 2023
Abstract Fusarium species are considered one of the most destructing plant pathogens. In current study, bimetallic zinc oxide-copper oxide nanoparticles (ZnO-CuO NPs) were myco-synthesized using Aspergillus fumigatus for controlling oxysporum growth. was isolated from soil and identified morphologically genetically. The ZnO-CuO NPs characterized UV-Vis, DLS, HR-TEM, SEM, XRD analyses. HR-TEM characterization method indicated that, biosynthesized appeared as semi-spherical with average diameter specified 54.18 ± 1.9 nm. DLS described characteristic particle size diffusion calculated 85.52 nm, 90.85 92.85 nm ZnO NPs, CuO respectively. Additionally, SEM image displays basic NP surface character exterior impression apparent. separated naturally spherical particles connected within fungal filtrate, which illuminated fused capped filtrate. Antifungal activity evaluated against F. . Results revealed that exhibited promising antifungal toward where inhibition zone at 1000 µg/ml 22.8 0.76 mm, MIC 125 µg/ml. Moreover, growth percentages different concentrations 1000, 500, 250, 88.9, 65.5, 41.1, 8.9% respectively, highest 88.9% concentration µg/ml, while lowest TEM ultrastructure results, treated a clear destruction found in all cell contents disintegration wall well plasma membrane. Also, nucleus small damaged shape chromatin materials distributed several dark stained bodies cytoplasm. conclusion, successfully A. , it had
Language: Английский
Citations
41
International Journal of Molecular Sciences, Journal Year: 2023, Volume and Issue: 24(19), P. 14897 - 14897
Published: Oct. 4, 2023
The misuse of antibiotics and antimycotics accelerates the emergence antimicrobial resistance, prompting need for novel strategies to combat this global issue. Metallic nanoparticles have emerged as effective tools combating various resistant microbes. Numerous studies highlighted their potential in addressing antibiotic-resistant fungi bacterial strains. Understanding mechanisms action these nanoparticles, including iron-oxide, gold, zinc oxide, silver is a central focus research within life science community. Various hypotheses been proposed regarding how exert effects. Some suggest direct targeting microbial cell membranes, while others emphasize release ions from nanoparticles. most compelling mechanism involves oxidative damage caused by nanoparticles-generated reactive oxygen species. This review aims consolidate knowledge, discuss properties metallic underscore alternatives enhance efficacy existing medications against infections antimicrobial-resistant pathogens.
Language: Английский
Citations
38
BMC Complementary Medicine and Therapies, Journal Year: 2023, Volume and Issue: 23(1)
Published: July 22, 2023
The overuse of antibiotics leads to the emergence antibiotic-resistant microbes which causes high mortality worldwide. Therefore, synthesis new active compounds has multifunctional activities are main challenge. Nanotechnology provides a solution for this issue.The endophytic fungal strain Aspergillus terreus BR.1 was isolated from healthy root Allium sativum and identified using internal transcribed spacer (ITS) sequence analysis. copper oxide nanoparticles (CuO-NPs) were synthesized by harnessing metabolites strain. UV-Visble spectroscopy, Fourier-transform infrared spectroscopy (FT-IR), Transmission electron micrscopy (TEM), Energy dispersive X-ray (EDX), diffraction (XRD), Dynamic light scattering (DLS), zeta potential (ζ) used characterization CuO-NPs. activity against different pathogenic bacteria Candida species investigated agar well-diffusion method. biocombatibility anticancer assessed MTT assay scavenging DPPH investigate antioxidant CuO-NPs.Data showed successful formation crystalline nature spherical shape CuO-NPs with sizes in ranges 15-55 nm. EDX reveals that as-formed sample contains ions C, O, Cl, Cu weight percentages 18.7, 23.82, 11.31, 46.17%, respectively. DLS ζ-potential homogeneity stability polydispersity index (PDI) 0.362 ζ-value - 26.6 mV. exhibited promising antibacterial anti-Candida (concentration-dependent) minimum inhibitory concentration (MIC) values 25-50 µg mL-1. Moreover, mediated-CuO-NPs targeted cancer cells MCF7 PC3 at low IC50 concentrations 159.2 ± 4.5 116.2 3.6 mL-1, respectively as compared normal (Vero Wi38 value 220.6 3.7 229.5 2.1 respectively). biosynthesized detected method 80.5 1.2% 1000 mL-1 decreased 20.4 4.2% 1.9 ascorbic acid (control) 97.3 0.2 37.5 1.3% same concentrations, respectively.The can be integrated into various biomedical theraputic applications.
Language: Английский
Citations
33
Journal of Drug Delivery Science and Technology, Journal Year: 2024, Volume and Issue: 96, P. 105695 - 105695
Published: April 21, 2024
Language: Английский
Citations
10
Archives of Microbiology, Journal Year: 2025, Volume and Issue: 207(3)
Published: Feb. 1, 2025
Language: Английский
Citations
1
International Journal of Microbiology, Journal Year: 2025, Volume and Issue: 2025(1)
Published: Jan. 1, 2025
The escalating threat of infectious diseases, exacerbated by antimicrobial resistance (AMR) and biofilm formation, necessitates innovative therapeutic strategies. This review presents a comprehensive exploration the potential nanoparticles synthesized from natural sources, including plant extracts, microbial products, marine compounds, as agents. These naturally derived demonstrated significant antibiofilm antivirulence effects, with specific examples revealing their capacity to reduce mass up 78% inhibit bacterial quorum sensing 65%. integration bioactive such polyphenols chitosan, facilitates nanoparticle stability enhances efficacy, while green synthesis protocols environmental risks. Notably, identifies silver using tea achieving 85% inhibition polymicrobial growth in vitro. Despite these promising results, challenges standardization scalability persist. study underscores transformative leveraging sourced sustainable alternatives conventional antimicrobials, offering quantitative insights for future application combating mono- infections.
Language: Английский
Citations
1
Pharmaceutics, Journal Year: 2023, Volume and Issue: 15(6), P. 1650 - 1650
Published: June 3, 2023
The ambition to combat the issues affecting environment and human health triggers development of biosynthesis that incorporates production natural compounds by living organisms via eco-friendly nano assembly. Biosynthesized nanoparticles (NPs) have various pharmaceutical applications, such as tumoricidal, anti-inflammatory, antimicrobials, antiviral, etc. When combined, bio-nanotechnology drug delivery give rise pharmaceutics with site-specific biomedical applications. In this review, we attempted summarize in brief types renewable biological systems used for metallic metal oxide NPs vital contribution biogenic carriers simultaneously. biosystem assembly further affects morphology, size, shape, structure produced nanomaterial. toxicity NPs, because their pharmacokinetic behavior vitro vivo, is also discussed, together some recent achievements towards enhanced biocompatibility, bioavailability, reduced side effects. Because large biodiversity, potential application extracts nanomedicine yet be explored.
Language: Английский
Citations
22
Environmental Research, Journal Year: 2024, Volume and Issue: 251, P. 118703 - 118703
Published: March 20, 2024
Language: Английский
Citations
6
Ceramics International, Journal Year: 2024, Volume and Issue: 50(17), P. 30843 - 30857
Published: May 25, 2024
Language: Английский
Citations
6