Innovative strategies for overcoming blood-brain barrier challenges in Alzheimer’s disease: A focus on green-synthesized metallic nanoparticles DOI

Kushagra Nagori,

Kartik T. Nakhate, Krishna Yadav

et al.

Inorganic Chemistry Communications, Journal Year: 2024, Volume and Issue: unknown, P. 113604 - 113604

Published: Nov. 1, 2024

Language: Английский

Variety and Duration of Different Sedentary Behaviors, Inflammation, Genetic Susceptibility, and New-Onset Dementia in the Older Population DOI
Sisi Yang, Ziliang Ye, Mengyi Liu

et al.

Journal of the American Medical Directors Association, Journal Year: 2023, Volume and Issue: 24(9), P. 1396 - 1404

Published: July 11, 2023

Language: Английский

Citations

5
Changes in cognitive ability and serum microRNA levels during aging in mice DOI Open Access
Keisuke Yamamoto,

K. Miyano,

M. Fujita

et al.

Experimental and Therapeutic Medicine, Journal Year: 2024, Volume and Issue: 27(3)

Published: Jan. 29, 2024

Mild cognitive impairment (MCI) is an early stage that can result in dementia. MCI be reversed, and diagnosis at crucial to control the progression Dementia currently diagnosed based on interviews screening tests; however, novel biomarkers must identified allow detection. Therefore, present study aimed identify form of blood microRNAs (miRNAs/miRs) for or Blood samples were collected from C57BL/6NJcl male mice four time points, including 4‑week‑old (4W), 8‑week‑old (8W), 36‑week‑old (36W) 58‑week‑old (58W), serum was isolated. Body weight total cholesterol levels increased, alkaline phosphatase decreased with aging. The 8W exhibited highest ability Morris water maze test, whereas 58W demonstrated ability. RNA concentrations 4W, 8W, 36W no significant differences. Furthermore, small detected all mice. miRNA microarray analysis revealed a >1.5‑fold increase expression two miRNAs (miR‑21a‑5p miR‑92a‑3p) decrease other (miR‑6769b‑5p miR‑709) compared those In future, we aim further analyze aged discover biomarkers.

Language: Английский

Citations

1
Pathogenesis of Dementia DOI

Haidar Kanso,

Mohammad Hadi Awde,

Zeina Rammal

et al.

Published: Jan. 1, 2024

Language: Английский

Citations

1
Analyzing public discourse of dementia from Spanish and English tweets: a comparative analysis with other neurological disorders DOI Creative Commons

Javier Domingo-Espiñeira,

Oscar Fraile‐Martínez, Cielo García‐Montero

et al.

Frontiers in Neurology, Journal Year: 2024, Volume and Issue: 15

Published: Oct. 24, 2024

Dementia comprise a broad spectrum of cognitive declines affecting 47 million people worldwide, with numbers projected to reach 131 by 2050. Predominantly associated older adults, dementia can also impact younger individuals, having significant on daily functioning the affected patients, relatives, caregivers and socioeconomic system. Recent research underscores utility social media, particularly X (previously designed as Twitter), in understanding public perceptions sentiments related neurological disorders. Despite some initial studies have explored X, broader deeper analysis this condition is still warranted.

Language: Английский

Citations

1
Innovative strategies for overcoming blood-brain barrier challenges in Alzheimer’s disease: A focus on green-synthesized metallic nanoparticles DOI

Kushagra Nagori,

Kartik T. Nakhate, Krishna Yadav

et al.

Inorganic Chemistry Communications, Journal Year: 2024, Volume and Issue: unknown, P. 113604 - 113604

Published: Nov. 1, 2024

Language: Английский

Citations

1