Emerging trends in polysaccharide based cryogel scaffold for skin tissue engineering DOI
Vinita Patole, Ganesh Ingavle, Isha Behere

et al.

International Journal of Polymeric Materials, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 19

Published: Aug. 5, 2024

Skin tissue engineering has emerged as a promising field for developing wound dressings and skin substitutes. Recently, cryogel based scaffolds have gained significant attention due to their biocompatibility, tunable properties porous structure resembling the native extracellular matrix. Polysaccharides like sodium alginate, chitosan, dextran, agarose are widely explored fabricating cryogels inherent biocompatibility bioactivity. The review begins by highlighting significance of in treating different dermatological conditions injuries. It then explores fundamental polysaccharide scaffolds, focusing on biodegradability, fabrication methods biomedical applications polysaccharides engineering. In addition, it potential integrating 3D 4D printing technologies enhance functionality these leading widespread adoption clinical settings healing personalized medicine offering tailored solutions repair regeneration. Overall, this emphasizes immense advancing engineering, novel healing, medicine.

Language: Английский

Recent Progress in 3D Printing Polymer‐Based Bone Scaffolds DOI Open Access
Ruiqi Feng,

Alice Chu,

Yunlong Guo

et al.

Advanced Engineering Materials, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 13, 2025

This review aims to summarize recent advances in 3D printing technologies for polymer‐based bone scaffolds, focusing on material applications and clinical implications. The applicable different materials are discussed with their characteristics application advantages, specifically the common techniques polymer used. Recent of 3D‐printed scaffolds multifunctionality (i.e., drug delivery, regeneration minimally invasive implantation) then presented provide guidance potential applications.

Language: Английский

Citations

1

4D printing polymeric biomaterials for adaptive tissue regeneration DOI
Zhe Wang, Duo Ma, Juan Liu

et al.

Bioactive Materials, Journal Year: 2025, Volume and Issue: 48, P. 370 - 399

Published: Feb. 22, 2025

Language: Английский

Citations

1

Application of Artificial Intelligence at All Stages of Bone Tissue Engineering DOI Creative Commons
E. R. Kolomenskaya, Vera V. Butova, Artem Poltavskiy

et al.

Biomedicines, Journal Year: 2023, Volume and Issue: 12(1), P. 76 - 76

Published: Dec. 28, 2023

The development of artificial intelligence (AI) has revolutionized medical care in recent years and plays a vital role number areas, such as diagnostics forecasting. In this review, we discuss the most promising areas AI application to field bone tissue engineering prosthetics, which can drastically benefit from AI-assisted optimization patient personalization implants scaffolds ways ranging visualization real-time monitoring implantation cases prediction, thereby leveraging compromise between specific architecture decisions, material choice, synthesis procedure. With emphasized crucial accuracy robustness developed algorithms, especially engineering, it was shown that rigorous validation testing, demanding large datasets extensive clinical trials, are essential, how through developing multidisciplinary cooperation among biology, chemistry with materials science, AI, these challenges be addressed.

Language: Английский

Citations

19

Advancements in 3D-4D printing of hydroxyapatite composites for bone tissue engineering. DOI
Vianni Chopra,

Valeria Fuentes-Velasco,

Samyr R. Nacif-Lopez

et al.

Ceramics International, Journal Year: 2024, Volume and Issue: 50(20), P. 38819 - 38840

Published: July 23, 2024

Language: Английский

Citations

8

Hydrogel for bone microenvironment: Strategy and application DOI
Guangfeng Li, Dongyang Zhou, Shihao Sheng

et al.

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 499, P. 156554 - 156554

Published: Oct. 12, 2024

Language: Английский

Citations

8

Advanced Hydrogel-Based Strategies for Enhanced Bone and Cartilage Regeneration: A Comprehensive Review DOI Creative Commons

Diego De León-Oliva,

Diego Liviu Boaru,

Roque Emilio Perez-Exposito

et al.

Gels, Journal Year: 2023, Volume and Issue: 9(11), P. 885 - 885

Published: Nov. 8, 2023

Bone and cartilage tissue play multiple roles in the organism, including kinematic support, protection of organs, hematopoiesis. and, above all, cartilaginous tissues present an inherently limited capacity for self-regeneration. The increasing prevalence disorders affecting these crucial tissues, such as bone fractures, metastases, osteoporosis, or osteoarthritis, underscores urgent imperative to investigate therapeutic strategies capable effectively addressing challenges associated with their degeneration damage. In this context, emerging field engineering regenerative medicine (TERM) has made important contributions through development advanced hydrogels. These crosslinked three-dimensional networks can retain substantial amounts water, thus mimicking natural extracellular matrix (ECM). Hydrogels exhibit exceptional biocompatibility, customizable mechanical properties, ability encapsulate bioactive molecules cells. addition, they be meticulously tailored specific needs each patient, providing a promising alternative conventional surgical procedures reducing risk subsequent adverse reactions. However, some issues need addressed, lack strength, inconsistent low-cell viability. This review describes structure regeneration tissue. Then, we overview hydrogels, classification, synthesis, biomedical applications. Following this, most relevant recent hydrogels TERM regeneration.

Language: Английский

Citations

15

3D Bioprinting of Graphene Oxide-Incorporated Hydrogels for Neural Tissue Regeneration DOI
Jiahui Lai, Xiaodie Chen,

Helen H. Lu

et al.

3D Printing and Additive Manufacturing, Journal Year: 2024, Volume and Issue: 11(6), P. e2022 - e2032

Published: Jan. 19, 2024

Bioprinting has emerged as a powerful manufacturing platform for tissue engineering, enabling the fabrication of 3D living structures by assembling cells, biological molecules, and biomaterials into these structures. Among various biomaterials, hydrogels have been increasingly used in developing bioinks suitable bioprinting diverse human body tissues organs. In particular, hydrogel blends combining gelatin methacryloyl (GelMA; "GG hydrogels") receive significant attention owing to their many advantages, such excellent biocompatibility, biodegradability, intrinsic bioactive groups, polymer networks that combine thermoresponsive gelation feature chemically crosslinkable attribute GelMA. However, GG poor electroactive properties, which hinder applications neural engineering where electrical conductivity is required. To overcome this problem, study, small amount highly graphene oxide (GO) was added generate engineering. The incorporation GO nanoparticles slightly improved mechanical properties significantly increased hydrogels. All GO/GG composite exhibited shear thinning behavior sufficient viscosity hence could be printed porous scaffolds with good shape fidelity. Furthermore, rat bone marrow-derived mesenchymal stem cells (rBMSCs) bioprinted constructs high cell viability. provided ultraviolet (UV) shading effect facilitated survival during UV exposure after bioprinting. appear promising repairing damaged tissues.

Language: Английский

Citations

4

Nanostructures in Orthopedics: Advancing Diagnostics, Targeted Therapies, and Tissue Regeneration DOI Open Access
Wiktoria Frączek, Andrzej Kotela, Ireneusz Kotela

et al.

Materials, Journal Year: 2024, Volume and Issue: 17(24), P. 6162 - 6162

Published: Dec. 17, 2024

Nanotechnology, delving into the realm of nanometric structures, stands as a transformative force in orthopedics, reshaping diagnostics, and numerous regenerative interventions. Commencing with this scientific discipline empowers accurate analyses various diseases implant stability, heralding an era unparalleled precision. Acting carriers for medications, nanomaterials introduce novel therapeutic possibilities, propelling field towards more targeted effective treatments. In arthroplasty, nanostructural modifications to surfaces not only enhance mechanical properties but also promote superior osteointegration durability. Simultaneously, nanotechnology propels tissue regeneration, nanostructured dressings emerging pivotal elements accelerating wound healing. As we navigate frontiers nanotechnology, ongoing research illuminates promising avenues further advancements, assuring future where orthopedic practices are personalized highly efficient, captivating journey through groundbreaking innovations tailored patient care.

Language: Английский

Citations

4

Material extrusion 3D printing of bioactive smart scaffolds for bone tissue engineering DOI Creative Commons
Nasim Sabahi,

Iman Roohani,

Chunhui Wang

et al.

Additive manufacturing, Journal Year: 2025, Volume and Issue: unknown, P. 104636 - 104636

Published: Jan. 1, 2025

Language: Английский

Citations

0

Personalized solutions for ENT implants: The role of 3D/4D printing DOI Creative Commons
Jigar Vyas, Nensi Raytthatha,

Puja Vyas

et al.

Brazilian Journal of Pharmaceutical Sciences, Journal Year: 2025, Volume and Issue: 61

Published: Jan. 1, 2025

Abstract 3D printing, a newer manufacturing technology, is gaining prominence in the pharmaceutical and healthcare sectors, particularly ENT implants. It enables production of customized biological tissue scaffolds, portable models, surgical training aids. The emergence 4D printing offers potential for enhancing therapy safety efficacy. manuscript explores to revolutionize clinical practice, enabling development personalized drug formulations, patient-centric implants, anatomical models. This review delves into emerging concept “smart” biomaterials used which are capable mimicking natural tissues responding external stimuli. paves way significant advancements engineering with increase treatment highlights importance staff translating innovations practice successful adoption. transformative impact industries. bioprinting technologies revolutionizing therapy, offering novel avenues improved patient care fostering field.

Language: Английский

Citations

0