Antibacterial Activity of Zinc Oxide Nanoparticles Loaded with Essential Oils

Pharmaceutics, Journal Year: 2023, Volume and Issue: 15(10), P. 2470 - 2470

Published: Oct. 15, 2023

One major problem with the overuse of antibiotics is that microorganisms acquire resistance; thus dose must be increased unsustainably. To overcome this problem, researchers from around world are actively investigating new types antimicrobials. Zinc oxide (ZnO) nanoparticles (NPs) have been proven to exhibit strong antimicrobial effects; moreover, Food and Drugs Administration (FDA) considers ZnO as GRAS (generally recognized safe). Many essential oils activity their components do not generate resistance over time. drawbacks high volatility some components, which diminishes action they eliminated. The combination NPs can synergistically produce a stronger effect, volatile compounds retained on nanoparticles' surface, ensuring better-lasting effect. samples were characterized X-ray diffraction (XRD), transmission electron microscopy (TEM), scanning (SEM), Fourier transform infrared spectroscopy (FTIR), ultraviolet-visible (UV-Vis), thermal analysis (TG-DSC) coupled evolved gases using FTIR. NPs, size ~35 nm, exhibited loading between 1.44% 15.62%-the lower values specific for limonene-containing (e.g., orange, grapefruit, bergamot, or limette), while obtained cinnamon, minzol, thyme, citronella, lavender oils-highlighting differences among non-polar terpenes alcohol aldehyde derivatives. antibacterial assay indicated existence synergic dependency percentage loaded oil. Loaded offer immense potential development materials applications, such wound dressings food packaging. These utilized in scenarios where burst delivery desired when prolonged sought.

Language: Английский

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ZnO nanostructures – Future frontiers in photocatalysis, solar cells, sensing, supercapacitor, fingerprint technologies, toxicity, and clinical diagnostics

Coordination Chemistry Reviews, Journal Year: 2024, Volume and Issue: 515, P. 215942 - 215942

Published: May 20, 2024

Language: Английский

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Cutting-edge developments in zinc oxide nanoparticles: synthesis and applications for enhanced antimicrobial and UV protection in healthcare solutions

RSC Advances, Journal Year: 2024, Volume and Issue: 14(29), P. 20992 - 21034

Published: Jan. 1, 2024

This paper presents a comprehensive review of recent advancements in utilizing zinc oxide nanoparticles (ZnO NPs) to enhance antimicrobial and UV protective properties healthcare solutions.

Language: Английский

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Advancements in ZnO-Based Photocatalysts for Water Treatment: A Comprehensive Review

Crystals, Journal Year: 2024, Volume and Issue: 14(7), P. 611 - 611

Published: June 30, 2024

Water contamination remains a pressing global concern, necessitating the development of effective and sustainable water treatment solutions. Zinc oxide (ZnO) has garnered significant attention for its potential applications in photocatalysis due to unique properties versatile nature. This review synthesizes recent research findings on advancement ZnO-based photocatalysts treatment, encompassing synthesis methods, structure modifications photocatalytic efficiency enhancement, toxicity assessments, diverse processes. By critically analyzing strategies enhance performance ZnO role addressing pollution challenges, this provides valuable insights into evolving landscape achieving efficient environmentally friendly systems. emphasizes transformative revolutionizing methodologies underscores importance continued innovation harnessing ZnO’s capabilities purification.

Language: Английский

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Antimicrobial Hydroxyethyl-Cellulose-Based Composite Films with Zinc Oxide and Mesoporous Silica Loaded with Cinnamon Essential Oil

Pharmaceutics, Journal Year: 2024, Volume and Issue: 16(9), P. 1225 - 1225

Published: Sept. 19, 2024

: Cellulose derivatives are gaining much attention in medical research due to their excellent properties such as biocompatibility, hydrophilicity, non-toxicity, sustainability, and low cost. Unfortunately, cellulose does not exhibit antimicrobial activity. However, like hydroxyethyl represent a proper matrix incorporate agents with beneficial therapeutic effects.

Language: Английский

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Reusable and environmentally friendly cellulose nanofiber/titanium dioxide/chitosan aerogel photocatalyst for efficient degradation of tetracycline

Applied Surface Science, Journal Year: 2023, Volume and Issue: 641, P. 158425 - 158425

Published: Sept. 13, 2023

Language: Английский

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Facile Synthesis of Ni-Doped ZnO Nanoparticles Using Cashew Gum: Investigation of the Structural, Optical, and Photocatalytic Properties

Molecules, Journal Year: 2023, Volume and Issue: 28(23), P. 7772 - 7772

Published: Nov. 25, 2023

This work adopted a green synthesis route using cashew tree gum as mediating agent to obtain Ni-doped ZnO nanoparticles through the sol–gel method. Structural analysis confirmed formation of hexagonal wurtzite phase and distortions in crystal lattice due inclusion Ni cations, which increased average crystallite size from 61.9 nm 81.6 nm. These resulted growth point defects structure, influenced samples’ optical properties, causing slight reductions band gaps significant increases Urbach energy. The fitting photoluminescence spectra an increase concentration zinc vacancy (VZn) monovacancies (Vo) Zn cations were replaced by structure. percentage VZn for pure compound was 11%, increasing 40% 47% samples doped with 1% 3% respectively. In contrast, highest VO is recorded material lowest ions concentration, comprising about 60%. influence dopant also reflected photocatalytic performance. Among tested, Zn0.99Ni0.01O presented best result MB degradation, reaching efficiency 98.4%. Thus, recovered underwent reuse tests, revealing 98.2% dye confirming stability photocatalyst. Furthermore, use different inhibitors indicated that •OH radicals are main ones involved removing pollutant. valuable because it presents ecological gum, natural polysaccharide has been little explored literature.

Language: Английский

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Functionalized ZnO-Based Nanocomposites for Diverse Biological Applications: Current Trends and Future Perspectives

Nanomaterials, Journal Year: 2024, Volume and Issue: 14(5), P. 397 - 397

Published: Feb. 21, 2024

The wide array of structures and characteristics found in ZnO-based nanostructures offers them a versatile range uses. Over the past decade, significant attention has been drawn to possible applications these materials biomedical field, owing their distinctive electronic, optical, catalytic, antimicrobial attributes, alongside exceptional biocompatibility surface chemistry. With environmental degradation an aging population contributing escalating healthcare needs costs, particularly developing nations, there's growing demand for more effective affordable devices with innovative functionalities. This review delves into particular essential facets different synthetic approaches (chemical green) that contribute production multifunctional nano-ZnO particles applications. Outlining conjugation ZnO nanoparticles highlights enhancement capacity while lowering toxicity. Additionally, recent progress study nano-biomaterials tailored purposes is explored, including biosensing, bioimaging, tissue regeneration, drug delivery, as well vaccines immunotherapy. final section focuses on particles' toxicity mechanism special emphasis neurotoxic potential, primary pathways, providing overall up-to-date development future perspectives biomedicine field.

Language: Английский

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Silk fibroin-based scaffolds for wound healing applications with metal oxide nanoparticles

Journal of Drug Delivery Science and Technology, Journal Year: 2024, Volume and Issue: 96, P. 105689 - 105689

Published: April 21, 2024

In the last few years, wound healing and development of "ideal" biomaterials that provide quick recovery minimize scarring have represented one most important priorities researchers. this direction, silk fibroin (SF) scaffolds gained substantial awareness, as a promising polymer owing to their increased biocompatibility, outstanding mechanical properties, biodegradability, especially tensile strength. Furthermore, SF is acknowledged accelerate process by encouraging cell growth proliferation, also migration different types cells are included in stages process. Therefore, metal oxide nanoparticles (NPs), such iron (FeO), copper (CuO), zinc (ZnO), or magnesium (MgO) NPs, been extensively researched for antimicrobial properties ability enhance tissue regeneration addition SF. When introduced within scaffolds, these NPs impart enhanced including improved scaffold stability durability. Moreover, presence could increase biocompatibility facilitating adhesion, migration, ultimately promoting processes. The incorporation other natural polymers into has thus emerged favorable method therapeutic potential developed biomaterial. This review aims an overview advancements containing applications.

Language: Английский

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Optimizing Antimicrobial Efficacy: Investigating the Impact of Zinc Oxide Nanoparticle Shape and Size

Nanomaterials, Journal Year: 2024, Volume and Issue: 14(7), P. 638 - 638

Published: April 6, 2024

Zinc oxide nanoparticles (ZnO NPs) have been investigated due to their distinct properties, variety of structures and sizes, mainly for antimicrobial activity. They received a positive safety evaluation from the European Food Safety Authority (EFSA) packaging applications as transparent ultraviolet (UV) light absorbers based on absence significant migration zinc in particulate form. ZnO NPs with different morphologies (spherical, flower, sheet) synthesized via sol–gel methods extensively characterized by several solid-state techniques, namely vibrational spectroscopy, powder X-ray diffraction (XRD), scanning electron microscopy/energy dispersive spectroscopy (SEM/EDS), Fourier Transform Infrared Spectroscopy (FTIR), ultraviolet–visible (UV-VIS), paramagnetic resonance (EPR), nitrogen adsorption–desorption isotherms. The were assessed antibacterial activity against Escherichia coli (gram-negative bacteria) Staphylococcus aureus (gram-positive study influence morphology size efficacy. sizes demonstrated both bacteria. highest microbial cell reduction rate (7–8 log CFU mL−1 E. 6–7 S. aureus) was obtained sheet- spherical-shaped result high specific surface area. In fact, higher areas (18.5 13.4 m2 g−1, respectively), compared flower-shaped (5.3 m2g−1), seem promote more efficient bacterial reduction. particles also smaller (31 nm) (233 × 249 ones. flower NP resulted 4–5 3–4 aureus. lower apparent could be associated either lack defects particle core or shape shielding effect. Compared aureus, seems less resistant NPs, which may explained characteristics its membrane. With simple synthesis do not allow controlled simultaneously, it is challenge elucidate effect each these two parameters performance.

Language: Английский

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