Greener Journal of Biomedical and Health Sciences,
Journal Year:
2024,
Volume and Issue:
7(1), P. 61 - 72
Published: Nov. 19, 2024
The
rising
global
consumption
of
sugar,
mainly
through
sugar-sweetened
beverages,
presents
a
growing
public
health
concern
due
to
its
potential
negative
impact
on
eye
health.
This
paper
explores
the
complex
relationship
between
excessive
sugar
intake
and
various
diseases,
including
diabetic
retinopathy,
cataracts,
glaucoma,
focusing
biological
mechanisms
involved,
such
as
metabolic
dysregulation,
oxidative
stress,
inflammation.
found
that
epidemiological
evidence
has
consistently
linked
high
an
increased
prevalence
these
conditions,
highlighting
need
for
interventions
mitigate
this
risk.
burden
sugar-related
diseases
places
significant
pressure
healthcare
systems,
social
equity,
economic
productivity.
Vulnerable
populations,
children,
elderly,
those
with
pre-existing
face
heightened
risks.
Therefore,
addressing
challenges
requires
multifaceted
approach,
incorporating
policies
reduce
consumption,
improve
education
healthy
dietary
habits,
promote
community-based
initiatives
intake.
Recommendations
include
implementing
taxes,
improving
food
labeling,
fostering
collaboration
providers
policymakers
safeguard
enhance
outcomes.
Continued
research
into
long-term
effects
is
essential
refining
strategies
ensuring
better
outcomes
at-risk
populations.
Accepted:
05/11/2024
Published:
19/11/2024
*Corresponding
Author
Sylvester
Chibueze
Izah
E-mail:
[email protected]
Keywords:
Sugar
Eye
health,
Diabetic
Retinopathy,
Cataracts,
Glaucoma,
Public
International Journal of Molecular Sciences,
Journal Year:
2024,
Volume and Issue:
25(6), P. 3360 - 3360
Published: March 15, 2024
Reactive
oxygen
species
(ROS)
and
free
radicals
work
to
maintain
homeostasis
in
the
body,
but
their
excessive
production
causes
damage
organism.
The
human
body
is
composed
of
a
variety
cells
totaling
over
60
trillion
cells.
Each
cell
performs
different
functions
has
unique
lifespan.
lifespan
preprogrammed
genes,
death
that
have
reached
end
called
apoptosis.
This
contrary
necrosis,
which
premature
brought
about
by
physical
or
scientific
forces.
its
own
lifespan,
humans
estimated
be
up
120
years.
Elucidating
mechanism
single
will
lead
better
understanding
death,
and,
conversely,
exploring
mechanisms
life.
In
this
sense,
research
on
active
radicals,
are
implicated
biological
disorders
homeostasis,
requires
an
both
physicochemical
as
well
biochemical
aspects.
Based
discussion
above,
it
clear
see
dual
injuring
facilitating
living
organisms.
Food Science & Nutrition,
Journal Year:
2024,
Volume and Issue:
12(11), P. 8715 - 8741
Published: Oct. 16, 2024
Certain
carotene
components,
such
as
lycopene
and
beta-carotene,
are
found
in
tomatoes,
carrots,
sweet
potatoes,
etc.
good
for
human
health.
It
gives
plants
their
distinctive
red
color.
A
class
of
lipid-soluble
natural
pigments
known
carotenoids
is
the
precursor
vitamin
vital
antioxidant
defense
against
peroxides
cells
tissues.
This
review
provides
an
overview
current
state
knowledge
research
on
sources,
structures,
physiochemical
properties,
absorption
metabolism,
functional
advantages,
prevention
many
diseases
associated
with
beta-carotene.
These
antioxidants
have
been
linked
to
a
lower
risk
cardiovascular
disease
cancer,
they
also
help
draw
pollinators
flowers.
Carrots
potatoes
rich
sources
which
strengthens
immune
system
improves
eye
The
vivid
color
reproductive
organs,
including
flowers
fruits,
caused
by
carotenoid,
secondary
metabolite
that
produced
plastids.
other
health
advantages
attributed
lycopene.
When
ingested
through
food
or
supplements,
beta-carotene
manage
prevent
number
diseases,
metabolic,
inflammatory,
cardiovascular,
hepatic,
ophthalmic,
skeletal,
infertility
disorders.
main
point
toxicity
uncommon,
these
generally
accepted
be
safe
at
different
doses.
Including
nutrients
your
diet
can
improve
general
provide
illness
prevention.
Antibiotics,
Journal Year:
2025,
Volume and Issue:
14(3), P. 255 - 255
Published: March 1, 2025
Honey,
a
natural
product
with
rich
history
of
medicinal
use,
has
gained
increasing
recognition
for
its
potent
antimicrobial
properties,
particularly
against
antibiotic-resistant
pathogens.
This
review
focuses
on
the
mechanisms
honey,
including
efficacy
resistant
bacteria,
such
as
Methicillin-resistant
Staphylococcus
aureus
and
Pseudomonas
aeruginosa.
The
action
honey
is
multifactorial,
involving
hydrogen
peroxide
production,
phenolic
compounds,
high
sugar
concentrations,
presence
bee
defensin-1.
composition
varies
based
floral
source,
which
can
influence
strength.
Certain
types,
Manuka
are
effective
in
clinical
applications
due
to
their
higher
levels
bioactive
compounds.
Honey
also
been
shown
disrupt
bacterial
biofilms,
major
factor
antibiotic
resistance,
enhancing
therapeutic
potential
treating
chronic
wounds
infections,
especially
patients
compromised
immune
systems.
Moreover,
honey’s
ability
improve
wound
healing,
reduce
inflammation,
promote
tissue
regeneration
highlights
broad
profile.
As
resistance
continues
challenge
modern
healthcare,
offers
promising
complementary
treatment
therapy.
Research
into
specific
components
synergistic
effects
other
agents,
like
ginger
propolis,
could
expand
applications.
Standardizing
products
medical
use
establishing
guidelines
essential
optimizing
benefits.
scientific
understanding
deepens,
integration
healthcare
systems
an
adjunct
therapy
expected
increase,
offering
alternative
fight
infectious
diseases.
Pharmaceuticals,
Journal Year:
2025,
Volume and Issue:
18(3), P. 403 - 403
Published: March 13, 2025
Background:
Carotenoids
are
bioactive
tetraterpenoid
C40
pigments
that
actively
synthesized
by
plants,
bacteria,
and
fungi.
Compounds
such
as
α-carotene,
β-carotene,
lycopene,
lutein,
astaxanthin,
β-cryptoxanthin,
fucoxanthin,
zeaxanthin
have
attracted
increasing
attention
for
their
antiaging
properties.
They
exhibit
antioxidant,
neuroprotective,
anti-inflammatory
properties,
contributing
to
the
prevention
treatment
of
age-related
diseases.
Objectives:
The
aim
this
study
was
comprehensively
analyze
pharmacological
potential
biological
mechanisms
carotenoids
associated
with
disorders
evaluate
application
in
nutraceuticals,
pharmaceuticals,
cosmeceuticals.
Methods:
A
systematic
review
studies
published
over
past
two
decades
conducted
using
databases
PubMed,
Scopus,
Web
Science.
selection
criteria
included
clinical,
silico,
vivo,
vitro
investigating
therapeutic
effects
carotenoids.
Results:
demonstrate
a
variety
health
benefits,
including
macular
degeneration,
cancer,
cognitive
decline,
metabolic
disorders,
skin
aging.
Their
role
nutraceuticals
is
well
supported
ability
modulate
oxidative
stress
inflammatory
pathways.
In
show
promising
results
formulations
targeting
neurodegenerative
diseases
disorders.
cosmeceuticals,
they
improve
protecting
it
against
UV
radiation
damage.
However,
bioavailability,
optimal
dosages,
toxicity,
interactions
other
compounds
remain
critical
factors
maximize
efficacy
still
require
careful
evaluation
scientists.
Conclusions:
interventions
applications
fields.
Further
research
needed
optimize
formulas,
confirm
long-term
safety
effectiveness,
especially
aging
population.
Nutrients,
Journal Year:
2024,
Volume and Issue:
16(11), P. 1681 - 1681
Published: May 29, 2024
Aging
and
its
related
disorders
are
important
issues
nowadays
the
first
cause
of
this
physio-pathological
condition
is
overproduction
ROS.
Ascorbic
acid
an
antioxidant
mediator
anti-aging
proprieties
well
known.
Our
previous
data
demonstrated
that
Voghera
sweet
pepper
(VP),
a
distinctive
type
cultivated
in
Italy,
particularly
rich
ascorbic
acid.
Based
on
these
data,
effect
mediated
by
extracts
edible
part
VP
was
evaluated
vitro
model
both
young
old
Normal
Human
Diploid
Fibroblasts
(NHDF).
Using
phase
contrast
microscopy,
we
observed
may
help
cells
maintenance
physiological
morphology
during
aging.
Cytofluorimetric
analyses
revealed
led
to
increase
DNA
synthesis
percentage
living
cells,
linked
consequent
mitotic
events.
This
hypothesis
supported
enhancement
PCNA
expression
levels
old,
treated
fibroblasts,
corroborating
idea
extract
could
recover
phenotype
adult
confirmed
study
p16
p53
TEM
analyses.
results,
suppose
can
lead
partial
recovery
“young-like”
phenotypes
fibroblasts.
Biomedical Reports,
Journal Year:
2025,
Volume and Issue:
22(4)
Published: Feb. 14, 2025
Astaxanthin
(AXT),
a
carotenoid
primarily
derived
from
marine
organisms
such
as
shrimp,
krill
and
the
microalga
Haematococcus
pluvialis,
has
gained
significant
attention
for
its
potent
antioxidant,
anti‑inflammatory
anti‑proliferative
properties.
The
present
comprehensive
review
explored
role
of
AXT
in
cancer
prevention
treatment,
emphasizing
cytotoxic
mechanisms
modulation
key
molecular
pathways
involved
progression.
demonstrated
efficacy
across
variety
types,
including
nervous
system,
breast
gastrointestinal
cancers,
through
ability
to
induce
apoptosis,
inhibit
metastasis
disrupt
cell
growth.
detailed
both
in
vitro
vivo
studies
highlighting
effectiveness
sensitizing
cells
chemotherapy,
thereby
enhancing
therapeutic
outcomes
potentially
reducing
treatment‑related
side
effects.
incorporation
nanoparticle‑based
delivery
systems
further
improved
bioavailability
targeted
action,
showcasing
potential
advanced
therapies.
However,
despite
promising
experimental
results,
more
clinical
trials
are
necessary
validate
safety
human
populations.
Such
research
would
help
standardize
dosing,
confirm
interactions
with
conventional
treatments
support
integration
into
oncology
natural,
complementary
approach
existing
treatments.
