International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(14), P. 7646 - 7646
Published: July 12, 2024
Chronic kidney disease (CKD) causes specific hormonal disturbances, such as variations in leptin and testosterone levels function. These disturbances can promote errors signaling interaction cellular information processing be implicated the pathogenesis of atherosclerosis. This study investigates factors that affect CKD patients examines how is related to markers vascular disease. We conducted a cross-sectional 162 with pre-dialysis dialysis stages. recorded clinical laboratory data, including leptin, testosterone, subclinical atherosclerosis like brachial–ankle pulse wave velocity (ba PWV) flow-mediated vasodilation (FMD) nitroglycerin-mediated (NMD) hemodialysis (HD) patients. Leptin was significantly correlated stages (p < 0.001) also HD = 0.026), adipose tissue mass 0.001), 0.001). In women patients, NMD 0.039; r −0.379); all C reactive protein 0.007; 0.28) parathormone −0.220). Our research emphasizes connection between tissue, CKD. associated inflammatory syndrome parathyroid hormone
Language: Английский