ACS Applied Materials & Interfaces, Journal Year: 2024, Volume and Issue: unknown
Published: Dec. 16, 2024
Current wound dressings are insufficient in simultaneously addressing bacterial infections and oxidative stress, which severely affects healing outcomes. To solve this problem, we introduced poly(ionic liquid) (PIL) with strong antibacterial properties cerium oxide nanoparticles (CeO
Language: Английский
Gels, Journal Year: 2025, Volume and Issue: 11(2), P. 123 - 123
Published: Feb. 7, 2025
Recent advancements in wound dressing materials have significantly improved acute and chronic management by addressing challenges such as infection control, moisture balance, enhanced healing. Important progress has been made, especially with hydrogels, foams, antimicrobial for creating optimized dressings. Hydrogels are known maintaining optimal levels, while foam dressings excellent exudate absorbents. Meanwhile, incorporates various agents to reduce risks. These options healing time focusing on customized patient needs. Therefore, this review highlights the newest research prototypes applications, emphasizing their particular benefits clinical importance. Innovations stimuli-responsive hydrogels hybrid bioengineered composites discussed relation properties, including responsiveness pH, temperature, glucose, or enzymes drug delivery precision. Moreover, ongoing trials included, demonstrating potential of emerging solutions be soon translated from laboratory settings. By discussing interdisciplinary approaches that integrate advanced materials, nanotechnology, biological insights, work provides a contemporary framework patient-centric, efficient care strategies.
Language: Английский
Citations
4
International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: 298, P. 140082 - 140082
Published: Jan. 18, 2025
Language: Английский
Citations
3
Journal of Composites Science, Journal Year: 2025, Volume and Issue: 9(3), P. 133 - 133
Published: March 13, 2025
Severe skin injuries such as burns and chronic wounds are a subject of interest in the medical field, they require much attention. These types susceptible to serious complications, which can worsen health patients reduce their quality life. Hydrogels have emerged innovative wound dressings for treating acute wounds, including burns, diabetic foot ulcers, venous leg pressure ulcers. polymeric networks provide moist environment, promote cellular migration, offer antimicrobial properties, being recognized superior conventional dressings. This review aims explore recent advancements hydrogel-based dressings, emphasizing state-of-the-art technologies used this purpose trend achieving personalized therapeutic approaches. Despite promising vitro vivo findings described review, further clinical validation large-scale manufacturing optimizations required widespread adoption.
Language: Английский
Citations
3
Frontiers in Bioengineering and Biotechnology, Journal Year: 2025, Volume and Issue: 12
Published: Jan. 10, 2025
Bacterial infection, a complex wound microenvironment, and persistent inflammatory response in acute wounds can result delayed healing abnormal scar formation, thereby compromising the normal function aesthetic appearance of skin tissue. This issue represents one most challenging problems clinical practice. study aims to develop hydrogel dressing specifically designed for treatment wounds, providing immediate effective protection affected areas. innovation seeks offer novel advanced solution management wounds. In this study, composite scaffold was synthesized through reaction between oxidized glycyrrhizic acid carboxymethyl chitosan Schiff base. The material properties were systematically characterized, its biocompatibility antibacterial efficacy rigorously evaluated. A rat model established compare multiple groups, assessing impact on microenvironment repair. results demonstrated that OGA-CMCS exhibited excellent injectability, biocompatibility, properties. It capable enhancing which turn influenced polarization macrophages from M1 M2 phenotype, mitigating response, promoting angiogenesis granulation tissue regeneration, accelerating healing. successfully developed glycyrrhizin-based dressing, not only introduces innovative approaches emergency surface defects but also provides an experimental foundation. is anticipated contribute significantly addressing relevant challenges.
Language: Английский
Citations
0
Journal of Pharmaceutical Innovation, Journal Year: 2025, Volume and Issue: 20(1)
Published: Jan. 23, 2025
Language: Английский
Citations
0
Polymers for Advanced Technologies, Journal Year: 2025, Volume and Issue: 36(3)
Published: March 1, 2025
ABSTRACT The development of hydrogel wound dressings that facilitate rapid healing is a complex task, primarily due to the necessity integrating multiple functional attributes, including air permeability, adhesion, antibacterial efficacy, and biocompatibility. In this study, we employed fatty acid‐modified carboxymethyl chitosan (CMCS) fabricate multifunctional dressing. This dressing exhibits adjustable hydrophobicity, robust mechanical properties, potent activity, with polyacrylamide (PAM) tannic acid (TA) serving as primary constituents. study demonstrated incorporation hydrophobic structures significantly enhanced tensile strength, compressive adhesive capacity hydrogels. addition, release curve TA showed acids played vital role in enhancing properties hydrogels, which may increase TA. Furthermore, length carbon chain has significant effect on hydrogel. summary, TA/(C14‐g‐CMCS)/PAM excellent can effectively prevent bleeding, accelerate closure, promote tissue regeneration. Therefore, TA/(FA‐g‐CMCS)/PAM hydrophobicity expected be best candidate for accelerating promoting regeneration skin tissue.
Language: Английский
Citations
0
Materials Today Chemistry, Journal Year: 2025, Volume and Issue: 45, P. 102639 - 102639
Published: March 15, 2025
Language: Английский
Citations
0
International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 142082 - 142082
Published: March 1, 2025
Language: Английский
Citations
0
Acta Biomaterialia, Journal Year: 2025, Volume and Issue: unknown
Published: April 1, 2025
Language: Английский
Citations
0
Polymers, Journal Year: 2025, Volume and Issue: 17(8), P. 1114 - 1114
Published: April 20, 2025
The lack of personalized wound dressings tailored to individual needs can significantly hinder healing. Hydrogels offer a promising solution, as they be engineered mimic the extracellular matrix (ECM), providing an optimal environment for repair. integration digital light processing (DLP), high-resolution 3D printing process, allows precise customization hydrogel-based dressings. In this study, gelatin methacrylate (GelMA)-based formulations were prepared in combination with three different polymeric precursors: methacrylated hyaluronic acid (HAMA), poly (ethylene glycol) diacrylate (PEGDA) and allyl cellulose (MCCA). These precursors used print micropatterned patches. printed constructs revealed high gel content good resistance hydrolytic degradation. To improve adhesive antioxidant properties patches, gallic (GA) was incorporated through surface functionalization. This enabled scavenging approximately 80% free radicals within just 4 h. also improved, further enhancement observed upon addition Fe3+ ions. vitro cytocompatibility tests using fibroblast (NHDF) cell line confirmed suitability materials biomedical applications. Thus, study demonstrates potential DLP-printed hydrogels advanced dressing materials.
Language: Английский
Citations
0