Impact of respiratory viral infections during pregnancy on the neurological outcomes of the newborn: current knowledge DOI Creative Commons
Sara Manti,

Giulia Spoto,

Antonio Gennaro Nicotera

et al.

Frontiers in Neuroscience, Journal Year: 2024, Volume and Issue: 17

Published: Jan. 8, 2024

Brain development is a complex process that begins during pregnancy, and the events occurring this sensitive period can affect offspring's neurodevelopmental outcomes. Respiratory viral infections are frequently reported in pregnant women, and, last few decades, they have been related to numerous neuropsychiatric sequelae. viruses disrupt brain by directly invading fetal circulation through vertical transmission or inducing neuroinflammation maternal immune activation production of inflammatory cytokines. Influenza virus gestational infection has consistently associated with psychotic disorders, such as schizophrenia autism spectrum disorder, while recent pandemic raised some concerns regarding effects severe acute respiratory syndrome coronavirus 2 on outcomes children born affected mothers. In addition, emerging evidence supports possible role syncytial risk factor for adverse consequences. Understanding mechanisms underlying developmental dysfunction allows improving preventive strategies, early diagnosis, prompt interventions.

Language: Английский

Detecting Autism Spectrum Disorder and Attention Deficit Hyperactivity Disorder Using Multimodal Time-Frequency Analysis with Machine Learning Using the Electroretinogram from Two Flash Strengths DOI
Sultan Mohammad Manjur, Luís Roberto Mercado Díaz, Irene Lee

et al.

Journal of Autism and Developmental Disorders, Journal Year: 2024, Volume and Issue: unknown

Published: Feb. 23, 2024

Language: Английский

Citations

6
A systematic review of artificial neural network techniques for analysis of foot plantar pressure DOI Creative Commons

Chongguang Wang,

Kerrie Evans,

Dean S. Hartley

et al.

Journal of Applied Biomedicine, Journal Year: 2024, Volume and Issue: 44(1), P. 197 - 208

Published: Jan. 1, 2024

Plantar pressure distribution offers insights into foot function, gait mechanics, and foot-related issues. This systematic review presents an analysis of the use artificial neural network techniques in context plantar analysis. 60 studies were included review. Sample size, pathology, sensor number, data collection device, utilization other devices, ground-truth methods, pre-processing dataset, type, evaluation metrics evaluated. Utilization customized wearable footwear devices for acquisition was common amongst both healthy participants patients. Inertial measurement units emerged as effective compensatory measure to address limitations associated with pressure. Ground truth methods predominantly relied on usage annotations reference devices. Multilayer perceptron, convolutional networks, recurrent networks identified most frequently employed algorithms across reviewed studies. Finally, performance largely drew upon statistical descriptions machine learning methods. provides a comprehensive understanding analysis, highlighting opportunities future research.

Language: Английский

Citations

5
Tackling myelin deficits in neurodevelopmental disorders using drug delivery systems DOI
May Rokach, Corinne Portioli, Sayanti Brahmachari

et al.

Advanced Drug Delivery Reviews, Journal Year: 2024, Volume and Issue: 207, P. 115218 - 115218

Published: Feb. 24, 2024

Language: Английский

Citations

5
Access and barriers to supports for children and caregivers attending public child developmental assessment services: Findings from the Sydney child neurodevelopment research registry DOI Creative Commons
Kelsie A. Boulton, Marie Antoinette Redoblado-Hodge,

Kelera Levu

et al.

Autism Research, Journal Year: 2023, Volume and Issue: 17(3), P. 555 - 567

Published: Nov. 27, 2023

Abstract Families can spend years waiting for a developmental assessment. We sought to understand supports caregivers had accessed by the time of their child's first multi‐disciplinary assessment, wanted, and barriers reported accessing these supports. also how government funding schemes (the National Disability Insurance Scheme) sociodemographic factors influenced access Caregivers were emailed questionnaires on background intervention history prior assessment at tertiary diagnostic service. Results from 202 showed most children receiving less than 2 hours support each week The common general practitioners pediatricians. behavioral therapists (41%) psychologists (29%) as desired but inaccessible child Half nominated need parenting interventions. frequent wait lists, finance, knowledge. Government improved total number services received (from 2.7 5.2 different services), disability specific only (e.g., speech occupational therapy). highlighted disparities families without funding, impacting certain groups over 7 years) mental health). Socioeconomic disadvantage, parental separation, and, surprisingly, being non‐culturally/linguistically diverse associated with fewer more barriers. highlight facilitate align existing recommendations.

Language: Английский

Citations

11
Pediatric dysphagia overview: best practice recommendation study by multidisciplinary experts DOI
Ebru Umay, Sibel Eyigör, Esra Giray

et al.

World Journal of Pediatrics, Journal Year: 2022, Volume and Issue: 18(11), P. 715 - 724

Published: July 11, 2022

Language: Английский

Citations

19
Long-term impact of serious neonatal bacterial infections on neurodevelopment DOI
Reenu Thomas, Merijn W. Bijlsma, Bronner P. Gonçalves

et al.

Clinical Microbiology and Infection, Journal Year: 2023, Volume and Issue: 30(1), P. 28 - 37

Published: April 19, 2023

Language: Английский

Citations

10
Apps and Digital Resources for Child Neurodevelopment, Mental Health, and Well-Being: Review, Evaluation, and Reflection on Current Resources DOI Creative Commons
Kelsie A. Boulton, Makana Hilton,

E. Michael Sutton

et al.

Journal of Medical Internet Research, Journal Year: 2025, Volume and Issue: 27, P. e58693 - e58693

Published: Jan. 1, 2025

Background An increase in the prevalence of neurodevelopmental conditions worldwide, alongside resource constraints within clinical services, has led to increased interest health information technologies, such as apps and digital resources. Digital tools are often viewed a solution bridge this divide supports for families. There is, however, paucity research that evaluated tools, their potential benefits child neurodevelopment associated concerns (eg, mental health, well-being), benefit Objective This study conducted first review existing mobile resources targeted at supporting needs children with developmental or conditions. Methods We identified 3435 separate resources, which 112 (43 69 resources) met criteria. These were categorized according purpose target then reviewed based on engagement, quality, evidence base using Adapted Mobile App Rating Scale. Results The most common condition concern by was autism (19/112, 17% resources), retrieved focusing challenging behaviors, promoting speech, language, social development, providing options alternative assistive communication. Other areas included language communication (16/112, 14.3%) attention-deficit/hyperactivity disorder (11/112, 9.8%). showed engaging, high levels accessibility functionality. Resources had various functions, including behavioral tasks children, support, scheduling journaling, advice, activities, strategies parents. quality credibility source was, mostly low. Apps good an largely developed partnership research, government institutions, rated significantly higher overall compared not institutions (apps; t41=–4.35, P<.001; resources; t67=–4.95, P<.001). Conclusions lack across means it is extremely difficult provide recommendations families respect may support needs. Frameworks development new discussed, highlighting novel approaches required demonstrate efficacy improving outcomes Such framework requires collaboration multiple stakeholders (software developers, researchers, regulatory bodies, clinicians, families) engagement expertise (app implementation, dissemination policy, regulations), harness neurodevelopment, juncture remains underdeveloped.

Language: Английский

Citations

0
Agreement Between Tele- and Face-to-Face Assessment of Neuromotor Development in High-Risk Children DOI Creative Commons

Ana Isabel Rubio-López,

Maríe Carmen Valenza, Julia Raya-Benítez

et al.

Applied Sciences, Journal Year: 2025, Volume and Issue: 15(2), P. 723 - 723

Published: Jan. 13, 2025

Background: Early interventions in high-risk children seek to improve prognosis, minimize developmental delays, and prevent functional deterioration. The objective of this study was evaluate the level agreement between face-to-face assessment tele-assessment neuromotor development 0 18 months age. Methods: Forty-five at high risk delays were included (33% female, mean gestational age 35.31 ± 4.03 weeks). patients a using Alberta Infant Motor Scale (AIMS) motor evolution (Niveaux d’Évolution Motrice, NEM) assessments. Results: analysis showed excellent interrater reliability (ρ ≥ 0.99) for AIMS. NEM almost perfect (kappa 0.81) most items. Seven them substantial = 0.61–0.80), one moderate 0.568), fair 0.338). Conclusions: This reveals an excellent/substantial items assessed. results are promising increase accessibility clinical diagnosis rehabilitation approach risk.

Language: Английский

Citations

0
The Ambiguous Role of Growth Factors in Autism: What Do We Really Know? DOI Open Access

Giulia Spoto,

Ambra Butera,

Maria Ludovica Albertini

et al.

International Journal of Molecular Sciences, Journal Year: 2025, Volume and Issue: 26(4), P. 1607 - 1607

Published: Feb. 13, 2025

Autism spectrum disorder (ASD) is a complex neurodevelopmental condition with multifactorial origins, including the potential involvement of neurotrophins and growth factors. These molecules, which are crucial for neuronal survival, synaptic plasticity, brain development, have been implicated in ASD pathophysiology. Altered levels such as NGF, BDNF, NT3, NT4, well factors like IGF1, VEGF, FGF, associated cognitive deficits, sensory processing abnormalities, behavioral issues patients. However, literature presents conflicting results, often due to differences research methodologies, sample sizes, patient populations, diagnostic criteria. Despite these inconsistencies, biomarkers therapeutic targets remains promising. Future standardized larger cohorts, clearer understanding genetic influences needed further elucidate their roles diagnosis treatment.

Language: Английский

Citations

0
Joint Angular Kinematics and Gross Motor Function in Typically Developing Healthy Children DOI Creative Commons
Monday Omoniyi Moses,

Ngozi Florence Onuegbu,

Prince De-Gualle Deku

et al.

Children, Journal Year: 2025, Volume and Issue: 12(3), P. 280 - 280

Published: Feb. 25, 2025

Objective: The aim of this study was to establish the interactions between joint angular kinematics and gross motor function in typically developing healthy Ghanaian children. Methods: A descriptive cross-sectional design employed. total 150 (69 (46.0%), 3.25 ± 0.08-year-old boys 81 (54.0%), 0.06-year-old girls) 2–4-year-old children were recruited. Joint kinematic variables [left hip flexion (LHF), left extension (LHE), right (RHF), knee (LKF), (RHE), (LKE), (RKF), ankle dorsi-flexion (LADF), (RKE), plantar (RAPF), (LAPF), (RADF)] (lying rolling, sitting, crawling kneeling, standing, walking, running, jumping) measured with standard scales. Results: correlations lying rolling vs. RHE (r = 0.221; p-value < 0.01), LKE −0.267; LAPF 0.264; RADF 0.240; 0.01); kneeling 0.196; 0.05) 0.188; 0.05); jumping −0.214; 0.01) −0.207; significant. Conclusions: There a negative correlation sampled population. Typically, should be exposed range motion, flexibility, active transportation programs for optimal lifestyles improvements skills.

Language: Английский

Citations

0