Long COVID Syndrome: A Narrative Review on Burden of Age and Vaccination DOI Open Access
Panaiotis Finamore, Elena Arena,

Domenica Marika Lupoi

et al.

Journal of Clinical Medicine, Journal Year: 2024, Volume and Issue: 13(16), P. 4756 - 4756

Published: Aug. 13, 2024

Background/Objective: The COVID-19 pandemic has led to the emergence of post-acute syndrome, also known as long COVID, which presents a significant challenge due its varied symptoms and unpredictable course, particularly in older adults. Similar infections, factors such age, pre-existing health conditions, vaccination status may influence occurrence severity COVID. objective is analyze role aging context COVID investigate prevalence rates efficacy improve prevention strategies treatment this age group. Methods: Four researchers independently conducted literature search PubMed database trace studies published between July 2020 2024. Results: Aging influences both likelihood developing recovery process, age-related physiological changes, immune system alterations, presence comorbidities. Vaccination plays key reducing risk by attenuating inflammatory responses associated with symptoms. Conclusions: Despite protection vaccines offer against severe infection, hospitalization, post-infection sequelae, vaccine hesitancy remains major obstacle, worsening impact Promising treatments for condition include antivirals although further research needed.

Language: Английский

Effects of Multidisciplinary Rehabilitation Program in Patients with Long COVID-19: Post-COVID-19 Rehabilitation (PCR SIRIO 8) Study DOI Open Access
Małgorzata Ostrowska, Alicja Rzepka-Cholasińska, Łukasz Pietrzykowski

et al.

Journal of Clinical Medicine, Journal Year: 2023, Volume and Issue: 12(2), P. 420 - 420

Published: Jan. 4, 2023

Up to 80% of COVID-19 survivors experience prolonged symptoms known as long COVID-19. The aim this study was evaluate the effects a multidisciplinary rehabilitation program in patients with composed physical training (aerobic, resistance, and breathing exercises), education, group psychotherapy. After 6 weeks 97 COVID-19, body composition analysis revealed significant decrease abdominal fatty tissue (from 2.75 kg 2.5 kg; p = 0.0086) concomitant increase skeletal muscle mass 23.2 24.2 0.0104). Almost participants reported dyspnea improvement assessed modified Medical Research Council scale. Patients’ capacity Minute Walking Test increased from 320 382.5 m (p < 0.0001), number repetitions 30 s Chair Stand improved 13 16 well fitness Short Physical Performance Battery 14 0.0001). impact fatigue on everyday functioning reduced Modified Fatigue Impact Scale 37 27 Cardiopulmonary exercise test did not show any change. has composition, dyspnea, patients.

Language: Английский

Citations

46

Practical Recommendations for Exercise Training in Patients with Long COVID with or without Post-exertional Malaise: A Best Practice Proposal DOI Creative Commons
Rainer Gloeckl, Ralf Harun Zwick,

Ulrich Fürlinger

et al.

Sports Medicine - Open, Journal Year: 2024, Volume and Issue: 10(1)

Published: April 24, 2024

Abstract People with long COVID may suffer from a wide range of ongoing symptoms including fatigue, exertional dyspnea, reduced exercise performance, and others. In particular, impaired performance is condition that can be recovered in many people through an individualized physical training program. However, clinical experience has shown the presence post-exertional malaise (PEM) significant barrier to COVID. Currently, there no guideline or consensus available on how apply this cohort. Therefore, we conducted literature review PubMed library using following search terms: “COVID”, “post-COVID”, “long COVID” “exercise” searching for studies January 2020 2024. Data 46 trials were included. Exercise regimes very heterogeneous none these reported management PEM context Based feedback additional survey was answered by 14 international experts field COVID, combined authors´ own extensive practical experience, best practice proposal recommendations been developed. This differentiates procedures according no, mild/moderate severe These guide allied healthcare professionals worldwide initiating adjusting programs stratified severity PEM.

Language: Английский

Citations

22

Effects of Pulmonary Rehabilitation on Respiratory Function and Thickness of the Diaphragm in Patients with Post-COVID-19 Syndrome: A Randomized Clinical Trial DOI Open Access
Katarzyna Anna Pietranis, Wiktoria Izdebska, Anna Kuryliszyn-Moskal

et al.

Journal of Clinical Medicine, Journal Year: 2024, Volume and Issue: 13(2), P. 425 - 425

Published: Jan. 12, 2024

Rehabilitation is an effective method for improving the overall health of patients who have experienced long-term effects COVID-19.

Language: Английский

Citations

7

Brain disorders: Impact of mild SARS-CoV-2 may shrink several parts of the brain DOI Open Access

Puranam Revanth Kumar,

B. Shilpa,

Rajesh Kumar Jha

et al.

Neuroscience & Biobehavioral Reviews, Journal Year: 2023, Volume and Issue: 149, P. 105150 - 105150

Published: March 31, 2023

Language: Английский

Citations

11

Medical Rehabilitation of Patients with Post-COVID-19 Syndrome—A Comparison of Aerobic Interval and Continuous Training DOI Open Access
Johanna M. Mooren, René Garbsch, Hendrik Schäfer

et al.

Journal of Clinical Medicine, Journal Year: 2023, Volume and Issue: 12(21), P. 6739 - 6739

Published: Oct. 25, 2023

Introduction: Post-COVID-19 syndrome (PCS) is a multisystemic disorder marked by impaired physical performance as one lead symptom. Since it has been suggested that endurance training part of medical rehabilitation may be effective in improving capacity PCS, this study aimed to compare different modes aerobic training. Methods: A total 110 PCS patients (49.3 ± 11.8 years; 38% women; time after infection = 260.2 127.5 days) underwent detailed clinical screening including symptom-limited cardiopulmonary exercise testing at admission and 4–6 weeks inpatient rehabilitation. Questionnaires were used assess disease perception. Patients performed controlled isocaloric cycle ergometer (3–5 sessions/week; 18 min) either continuous (CT) 50% maximal workload or interval (IT; load 60%, relief 30%). Outcomes compared coronary artery (CAD; n 96) evaluate overall effectiveness. Results: Training participation was comparable between the groups, with no indication training-specific exercise-induced fatigue. Overall, improved significantly mean 6.8 12.1% for W VT1; 3.1 10.0% VO2 5.5 14.7% O2 pulse 7.5 15.0% VO2peak; 2.7 11.0% VO2peak 4.6 12.4% (all p < 0.05) significant differences groups (p > 0.05). Both showed reduced levels fatigue, anxiety, depression well quality life wellbeing Compared guideline-based cardiac rehabilitation, similar improvement oxygen uptake CAD patients. Conclusion: benefit from moderate program terms The results are

Language: Английский

Citations

11

Gender-Related Effectiveness of Personalized Post-COVID-19 Rehabilitation DOI Open Access
Alicja Rzepka-Cholasińska, Jakub Ratajczak, Piotr Michalski

et al.

Journal of Clinical Medicine, Journal Year: 2024, Volume and Issue: 13(4), P. 938 - 938

Published: Feb. 6, 2024

Post-COVID-19 syndrome (PCS) may affect a substantial proportion of patients who have had COVID-19. The rehabilitation program might improve the physical capacity, functioning cardiopulmonary system, and mental conditions these patients. This study aimed to investigate effectiveness personalized in with PCS according gender.

Language: Английский

Citations

4

Improved Functioning and Activity According to the International Classification of Functioning and Disability after Multidisciplinary Telerehabilitation for Post-COVID-19 Condition—A Randomized Control Study DOI Open Access
Indrė Bilevičiūtė-Ljungar, Jan‐Rickard Norrefalk, Kristian Borg

et al.

Journal of Clinical Medicine, Journal Year: 2024, Volume and Issue: 13(4), P. 970 - 970

Published: Feb. 8, 2024

This study investigates the outcomes and feasibility concerning functioning activity of multidisciplinary group telerehabilitation for a post-COVID-19 condition. Recruitment rehabilitation was announced three times during 2021 2022 through COVID-19 patient organization in Sweden. The key inclusion criteria were remaining symptoms functional impairments beyond 12 weeks after SARS-CoV-2 infection; medical assessment treatment regarding comorbidities or new postinfection symptoms; ability to use Internet. Participants randomized into onto waiting list using an Internet program. Multiple included self-scored questionnaires physical tests before eight weeks, at six months follow-up. Here, we present on International Classification Functioning Disability questionnaire (ICF, 22 body functions 16 activity/participation categories) breathing scales. Of 164 participants who registered study, 67 (mean age 43, 78% women) participated eight-week compared 42 served as controls 47, 88% women). At follow-up, 60 from 21 completed data. results indicate that larger number ICF categories had improved months. Overall credibility, assessed by Credibility Expectancy Questionnaire, high, attrition rate low. beneficial people suffering Therefore, interventions should be further developed implemented clinical practice.

Language: Английский

Citations

4

Escala de estado funcional post-COVID-19: concordancia entre la versión administrada por evaluador versus autoevaluada en pacientes con síndrome post-COVID-19 DOI
Jhonatan Betancourt-Peña,

J. Rodriguez-Castro,

Valeria Pérez-Hortua

et al.

Rehabilitación, Journal Year: 2025, Volume and Issue: 59(1), P. 100878 - 100878

Published: Jan. 1, 2025

Language: Английский

Citations

0

Impact of underlying diseases and complications on COVID-19 mortality in South Korea: analysis of national health insurance service data DOI Creative Commons
Kyunghee Lee, Jieun Hwang

Archives of Public Health, Journal Year: 2025, Volume and Issue: 83(1)

Published: Jan. 23, 2025

Comorbidities or complications significantly influence coronavirus disease-2019 (COVID-19) severity and mortality risk. Therefore, this study aimed to compare treatment outcomes of COVID-19 inpatients by underlying diseases complications. Data on patients from the National Health Insurance Service customized research database were analyzed while focusing eight complications: diabetes, hypertension, heart disease, kidney liver dementia, depression, respiratory disease. Of 377,812 in 2021, 51.47% male 48.53% female, post-diagnosis was 2.04%; 68.7% (n = 259,560) had at least one condition, with following frequency: disease (78.88%), (33.84%), hypertension (30.29%), (21.38%), depression (9.32%), (4.89%), dementia (3.87%). Among without any diseases, 19.8% 74,925) treated for complications, (89.21%), (19.12%), (14.90%), diabetes (10.37%), (8.22%), (3.86%), (2.04%), (0.64%). Except all associated mortality. exhibited a 1.42-fold higher risk (95% confidence interval [CI ]1.35–1.50). All death, kidney-related conferring 4.84-fold CI 3.62–6.48). Underlying death. Even same timing onset, before after diagnosis, induced difference Both should be considered more proactive medical interventions.

Language: Английский

Citations

0

No impairment of maximal oxygen uptake, pulmonary function and walking economy in patients diagnosed with long COVID: consideration of disease severity DOI
Ole Kristian Berg,

Norun Aagård,

Jan Helgerud

et al.

European Journal of Applied Physiology, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 1, 2025

Language: Английский

Citations

0