Physical activity and neuroplasticity in neurodegenerative disorders: a comprehensive review of exercise interventions, cognitive training, and AI applications

Frontiers in Neuroscience, Journal Year: 2025, Volume and Issue: 19

Published: Feb. 28, 2025

This review aimed to elucidate the mechanisms through which (i) physical activity (PA) enhances neuroplasticity and cognitive function in neurodegenerative disorders, (ii) identify specific PA interventions for improving rehabilitation programs. We conducted a literature search PubMed, Medline, Scopus, Web of Science, PsycINFO, covering publications from January 1990 August 2024. The strategy employed key terms related neuroplasticity, exercise, function, personalized activity. Inclusion criteria included original research on relationship between while exclusion eliminated studies focusing solely pharmacological interventions. identified multiple pathways may enhance including releasing neurotrophic factors, modulation neuroinflammation, reduction oxidative stress, enhancement synaptic connectivity neurogenesis. Aerobic exercise was found increase hippocampal volume by 1–2% improve executive scores 5–10% older adults. Resistance training enhanced control memory performance 12–18% elderly individuals. Mind–body exercises, such as yoga tai-chi, improved gray matter density memory-related brain regions 3–5% emotional regulation 15–20%. Dual-task attention processing speed 8–14% individuals with disorders. also discuss potential role AI-based AI preventing rehabilitating illnesses, highlighting innovative approaches patient outcomes. significantly disorders various mechanisms. resistance training, mind–body practices, dual-task exercises each offer unique benefits. Implementing these activities clinical settings can Future should focus creating tailored conditions, incorporating programs optimize rehabilitation.

Language: Английский

The impact of sociodemographic, psychological, and quality of life factors on dual-task performance in elderly individuals: a cross-sectional study in Iraq

Aging & Mental Health, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 9

Published: Jan. 20, 2025

Objective This study aims to explore how sociodemographic, psychological, and quality of life factors impact dual-task performance among elderly individuals in Iraq.

Language: Английский

The Effect of Physical Exercise on Patients With Mild Cognitive Impairment: A Scoping Review

Cureus, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 8, 2024

Mild cognitive impairment (MCI) is characterized by a noticeable decline in abilities that not severe enough to significantly interfere with daily life or independent functioning. Recent research highlights the important role of exercise managing and improving function patients MCI. This scoping review examines benefits different forms function. Recommendations for exercise, including frequency, consistency, individualized programs, are discussed this review, an emphasis on importance safety regular monitoring. The integration physical training also suggested maximize benefits. Regular promising intervention mitigating overall quality

Language: Английский