Advancing Prosthetic Hand Capabilities Through Biomimicry and Neural Interfaces DOI
Mohammad Haghani Dogahe, Mark A. Mahan, Miqin Zhang

et al.

Neurorehabilitation and neural repair, Journal Year: 2025, Volume and Issue: unknown

Published: April 24, 2025

Background and Objectives Prosthetic hand development is undergoing a transformative phase, blending biomimicry neural interface technologies to redefine functionality sensory feedback. This article explores the symbiotic relationship between biomimetic design principles technology (NIT) in advancing prosthetic capabilities. Methods Drawing inspiration from biological systems, researchers aim replicate intricate movements capabilities of human through innovative designs. Central this endeavor NIT, facilitating seamless communication artificial devices nervous system. Recent advances fabrication methods have propelled brain–computer interfaces, enabling precise control hands by decoding activity. Results Anatomical complexities underscore importance understanding biomechanics, neuroanatomy, mechanisms for crafting effective solutions. Furthermore, achieving goal fully functional cyborg necessitates multidisciplinary approach body’s inherent By incorporating expertise clinicians, tissue engineers, bioengineers, electronic data scientists, next generation implantable not only anatomically biomechanically accurate but also offer intuitive control, feedback, proprioception, thereby pushing boundaries current technology. Conclusion integrating machine learning algorithms, biomechatronic principles, advanced surgical techniques, can achieve real-time while restoring tactile sensation proprioception. manuscript contributes novel approaches development, with potential implications enhancing functionality, durability, safety limb.

Language: Английский

A review of chitosan-based multifunctional nanocomposites for drug/gene/protein delivery and gene therapy in cancer treatments: Promises, challenges and outlooks DOI
Ali Khorasani, Seyed Morteza Naghib

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 141394 - 141394

Published: Feb. 1, 2025

Language: Английский

Citations

1
Polysaccharide-based chondroitin sulfate macromolecule loaded hydrogel/scaffolds in wound healing- A comprehensive review on possibilities, research gap, and safety assessment DOI
Shubhrajit Mantry,

Ashutosh Behera,

Shaktiprasad Pradhan

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 279, P. 135410 - 135410

Published: Sept. 6, 2024

Language: Английский

Citations

4
Cyclodextrin–Hydrogel Hybrids in Advanced Drug Delivery DOI Creative Commons
Hossein Omidian,

Arnavaz Akhzarmehr,

Erma J. Gill

et al.

Gels, Journal Year: 2025, Volume and Issue: 11(3), P. 177 - 177

Published: Feb. 28, 2025

Cyclodextrin (CD)–hydrogel hybrids have emerged as versatile and multifunctional drug delivery systems, offering enhanced solubility, controlled release, improved bioavailability. By combining the inclusion complexation properties of CDs with swelling retention capabilities hydrogels, these hybrid systems overcome key challenges in conventional formulations. This review explores CD composition, hydrogel polymer selection, fabrication techniques, release factors, real-world therapeutic applications. Additionally, latest advancements stimuli-responsive nanogels, microneedle-based are discussed. While CD–hydrogel demonstrate significant potential, scalability, regulatory hurdles, clinical translation remain challenges. Future research should focus on smart loading strategies, validation to bridge gap between laboratory innovations commercial

Language: Английский

Citations

0
Hydrogel-Based Biointerfaces: Recent Advances, Challenges, and Future Directions in Human–Machine Integration DOI Creative Commons
Aziz Ullah,

Do Youn Kim,

Sung In Lim

et al.

Gels, Journal Year: 2025, Volume and Issue: 11(4), P. 232 - 232

Published: March 23, 2025

Human–machine interfacing (HMI) has emerged as a critical technology in healthcare, robotics, and wearable electronics, with hydrogels offering unique advantages multifunctional materials that seamlessly connect biological systems electronic devices. This review provides detailed examination of recent advancements hydrogel design, focusing on their properties potential applications HMI. We explore the key characteristics such biocompatibility, mechanical flexibility, responsiveness, which are essential for effective long-term integration tissues. Additionally, we highlight innovations conductive hydrogels, hybrid composite materials, fabrication techniques 3D/4D printing, allow customization to meet demands specific HMI applications. Further, discuss diverse classes polymers contribute conductivity, including conducting, natural, synthetic, polymers, emphasizing role enhancing electrical performance adaptability. In addition material examine regulatory landscape governing hydrogel-based biointerfaces applications, addressing considerations clinical translation commercialization. An analysis patent insights into emerging trends shaping future technologies human–machine interactions. The also covers range neural interfaces, soft haptic systems, where play transformative Thereafter, addresses challenges face issues related stability, scalability, while perspectives continued evolution technologies.

Language: Английский

Citations

0
Advancing Eco-friendly Biomedicine: Sustainable Nanocomposites as Platforms for Genetic Vaccines DOI

Amin Hamidi,

Mahla Poudineh

Published: Jan. 1, 2025

Language: Английский

Citations

0
Advancing Prosthetic Hand Capabilities Through Biomimicry and Neural Interfaces DOI
Mohammad Haghani Dogahe, Mark A. Mahan, Miqin Zhang

et al.

Neurorehabilitation and neural repair, Journal Year: 2025, Volume and Issue: unknown

Published: April 24, 2025

Background and Objectives Prosthetic hand development is undergoing a transformative phase, blending biomimicry neural interface technologies to redefine functionality sensory feedback. This article explores the symbiotic relationship between biomimetic design principles technology (NIT) in advancing prosthetic capabilities. Methods Drawing inspiration from biological systems, researchers aim replicate intricate movements capabilities of human through innovative designs. Central this endeavor NIT, facilitating seamless communication artificial devices nervous system. Recent advances fabrication methods have propelled brain–computer interfaces, enabling precise control hands by decoding activity. Results Anatomical complexities underscore importance understanding biomechanics, neuroanatomy, mechanisms for crafting effective solutions. Furthermore, achieving goal fully functional cyborg necessitates multidisciplinary approach body’s inherent By incorporating expertise clinicians, tissue engineers, bioengineers, electronic data scientists, next generation implantable not only anatomically biomechanically accurate but also offer intuitive control, feedback, proprioception, thereby pushing boundaries current technology. Conclusion integrating machine learning algorithms, biomechatronic principles, advanced surgical techniques, can achieve real-time while restoring tactile sensation proprioception. manuscript contributes novel approaches development, with potential implications enhancing functionality, durability, safety limb.

Language: Английский

Citations

0